REACTION: R08838
Entry
R08838 Reaction
Name
benzoate,NADPH:oxygen oxidoreductase (2-hydroxylating)
Definition
Benzoate + NADPH + Oxygen <=> Salicylate + NADP+ + H2O
Equation
C00180
+
C00005
+
C00007
<=>
C00805
+
C00006
+
C00001
Comment
benzoic acid 2-hydroxylase (BA2H)
Reaction class
RC00001
C00005_C00006
RC00046
C00180_C00805
Enzyme
1.14.13.-
Pathway
rn00360
Phenylalanine metabolism
rn01110
Biosynthesis of secondary metabolites
Reference
1 [PMID:
7479795
]
Leon J, Shulaev V, Yalpani N, Lawton MA, Raskin I.
Benzoic acid 2-hydroxylase, a soluble oxygenase from tobacco, catalyzes salicylic acid biosynthesis.
Proc. Natl. Acad. Sci. U. S. A. 92 (1995) 10413-7.
LinkDB
DBGET
integrated database retrieval system
