REACTION: R08980
Entry
R08980 Reaction
Name
11beta,17beta-dihydroxy-4-androsten-3-one:NADP+ 17-oxidoreductase
Definition
11beta,17beta-Dihydroxy-4-androsten-3-one + NADP+ <=> 11beta-Hydroxyandrost-4-ene-3,17-dione + NADPH + H+
Equation
C18075
+
C00006
<=>
C05284
+
C00005
+
C00080
Comment
NAD+ (see
R08945
)
Reaction class
RC00001
C00005_C00006
RC00127
C05284_C18075
Enzyme
1.1.1.62
Pathway
rn00140
Steroid hormone biosynthesis
Orthology
K00044
17beta-estradiol 17-dehydrogenase [EC:
1.1.1.62
]
K10251
17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:
1.1.1.62
1.1.1.330
]
K13368
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
K13369
17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.105
1.1.1.239
]
K13370
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
K13373
17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:
1.1.1.62
1.1.1.270
]
LinkDB
DBGET
integrated database retrieval system
