KEGG   REACTION: R09442
Entry
R09442                      Reaction                               
Definition
7,12-Dimethylbenz[a]anthracene + Oxygen + NADPH + H+ <=> 7,12-Dimethylbenz[a]anthracene 5,6-oxide + H2O + NADP+
Equation
C19488 + C00007 + C00005 + C00080 <=> C19604 + C00001 + C00006
Comment
CYP1A1, CYP1B1
Reaction class
RC00001  C00005_C00006
RC01444  C19488_C19604
Enzyme
1.14.14.1
Pathway
rn00980  Metabolism of xenobiotics by cytochrome P450
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1
     R09442  7,12-Dimethylbenz[a]anthracene + Oxygen + NADPH + H+ <=> 7,12-Dimethylbenz[a]anthracene 5,6-oxide + H2O + NADP+
Orthology
K07408  cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
K07410  cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1]
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