| Entry |
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| Name |
S-adenosyl-L-methionine:malonyl-[acyl-carrier protein] O-methyltransferase
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| Definition |
S-Adenosyl-L-methionine + Malonyl-[acyl-carrier protein] <=> S-Adenosyl-L-homocysteine + Malonyl-[acp] methyl ester
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| Equation |
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| Comment |
Malonyl-[acp] is a far better acceptor of methyl groups from S-adenosyl-L-methionine than was malonyl-CoA.
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| Reaction class |
| C00019_C00021 | | C01209_C19673 |
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| Enzyme |
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| Pathway |
| Biotin metabolism | | Metabolic pathways |
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| Module |
| Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP |
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| Orthology |
| malonyl-CoA O-methyltransferase [EC: 2.1.1.197] |
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| Reference |
1 [PMID: 22965231]
Lin S, Cronan JE.
The BioC O-Methyltransferase Catalyzes Methyl Esterification of Malonyl-Acyl Carrier Protein, an Essential Step in Biotin Synthesis.
J. Biol. Chem. 287 (2012) 37010-20. |
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| LinkDB |
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