KEGG   REACTION: R11435Help
Entry
R11435                      Reaction                               

Definition
8 Malonyl-CoA + 7 NADPH + 7 H+ + Acyl-carrier protein <=> 3-Hydroxyhexadeca-4,6,8,10,12,14-hexaenoyl-[acp] + 8 CoA + 8 CO2 + 6 H2O + 7 NADP+
Equation
8 C00083 + 7 C00005 + 7 C00080 + C00229 <=> C21357 + 8 C00010 + 8 C00011 + 6 C00001 + 7 C00006
Pathway
Biosynthesis of enediyne antibiotics
Biosynthesis of antibiotics
Module
M00824  
9-membered enediyne core biosynthesis, malonyl-CoA => 3-hydroxyhexadeca-4,6,8,10,12,14-hexaenoyl-ACP => 9-membered enediyne core
M00825  
10-membered enediyne core biosynthesis, malonyl-CoA => 3-hydroxyhexadeca-4,6,8,10,12,14-hexaenoyl-ACP => 10-membered enediyne core
Orthology
K15314  
enediyne polyketide synthase
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