Rattus norvegicus (rat): 24205
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Entry
24205 CDS
T01003
Symbol
Apc
Name
(RefSeq) adenomatous polyposis coli protein
KO
K02085
adenomatosis polyposis coli protein
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04310
Wnt signaling pathway
rno04390
Hippo signaling pathway
rno04550
Signaling pathways regulating pluripotency of stem cells
rno04810
Regulation of actin cytoskeleton
rno04934
Cushing syndrome
rno05010
Alzheimer disease
rno05022
Pathways of neurodegeneration - multiple diseases
rno05165
Human papillomavirus infection
rno05200
Pathways in cancer
rno05206
MicroRNAs in cancer
rno05210
Colorectal cancer
rno05213
Endometrial cancer
rno05217
Basal cell carcinoma
rno05224
Breast cancer
rno05225
Hepatocellular carcinoma
rno05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
24205 (Apc)
04390 Hippo signaling pathway
24205 (Apc)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
24205 (Apc)
09142 Cell motility
04810 Regulation of actin cytoskeleton
24205 (Apc)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
24205 (Apc)
05206 MicroRNAs in cancer
24205 (Apc)
09162 Cancer: specific types
05210 Colorectal cancer
24205 (Apc)
05225 Hepatocellular carcinoma
24205 (Apc)
05226 Gastric cancer
24205 (Apc)
05217 Basal cell carcinoma
24205 (Apc)
05213 Endometrial cancer
24205 (Apc)
05224 Breast cancer
24205 (Apc)
09172 Infectious disease: viral
05165 Human papillomavirus infection
24205 (Apc)
09164 Neurodegenerative disease
05010 Alzheimer disease
24205 (Apc)
05022 Pathways of neurodegeneration - multiple diseases
24205 (Apc)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
24205 (Apc)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
rno01009
]
24205 (Apc)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
rno03036
]
24205 (Apc)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
rno04812
]
24205 (Apc)
Protein phosphatases and associated proteins [BR:
rno01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
24205 (Apc)
Chromosome and associated proteins [BR:
rno03036
]
Eukaryotic type
Centrosome formation proteins
Other centriole associated proteins
24205 (Apc)
Cytoskeleton proteins [BR:
rno04812
]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulin-binding proteins
EB / APC
24205 (Apc)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Arm_APC_u3
APC_basic
EB1_binding
APC_r
APC_u5
APC_rep
APC_u14
APC_u15
APC_u9
Arm
SAMP
APC_N_CC
APC_u13
APC_15aa
Suppressor_APC
Sec7-like_HUS
Motif
Other DBs
NCBI-GeneID:
24205
NCBI-ProteinID:
NP_036631
RGD:
2123
Ensembl:
ENSRNOG00000020423
UniProt:
P70478
LinkDB
All DBs
Position
18:26138382..26196021
Genome browser
AA seq
2842 aa
AA seq
DB search
MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTELETEASNMKEVLKQLQGSIEDETM
TSGQIDLLERLKEFNLDSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPRRA
FVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSLQT
DMTRRQLEYEARQIRAAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRVRQLLQSQAAEA
ERSSQSKHETASHEAERQLEGQGVAESNLATSGSGQSSAARVDHETAGVLSSSGTHSAPR
RLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLLHG
NDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETCWE
WQEAHEQGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQVD
CEMHGLTDDHYSVTLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQ
VIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTEN
KADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENNCL
QTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGS
AAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLSPK
ASHRSKQRHKQNLYGDYVFDASRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGSLD
SSRSEKDRSLERERGIGLSTYHSATENPGTSSKRGLQLSATAAQIAKVMEEVSALHTSQD
DRSPASAAELHCVAEERTAARRSSASHTHPNTHNFAKSESSNRTCSMPYAKVEYKRSSND
SLNSVTSSDGYGKRGQMKPSVESYSEDDEGKFCSYGQYPADLAHKIHSANHMDDNGGELD
TPINYSLKYSDEQLNSGRQSPSQNERWARPKHVIEDEIKQNEQRQSRSQNTNFPVYSENT
DDKHLKFQQHFGQQECVSPYRSRGTNGSETNRMGSSHAVNQNVNQSLCQEDDYEDDKPTN
YSERYSEEEQHEEEERPTNYSIKYNEEKHHVDQPIDYSLKYATDISSSQKPSFSFSKTPS
VQGTKTEHNSPSSEAASAPSSNAKRQSQLHPSSAQRNGQTPKGTACKVPSINQETMQTYC
VEDTPICFSRCSSLSSLSSAEDEIGCDQTTQEADSANTLQIAEIKENDVTRSAQDPASDV
PAVSQSTRTKPSRLQASGLASESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLV
FSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIVSPSDLPDSPGQTMPPSRSKTPPPPP
PPQPVQTKREVPKTKVPAAEQREGGPKQTAVSAAVQRVQVLPDADTLLHFATESTPDGFS
CSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETEPEQPEESNENQDKEVEKPDSEKD
LLDDSDDDDIEILEECIISAMPTKSSRKAKKLAQTASKLPPPVARKPSQLPVYKLLPSQS
RLQAQKHVSFTPGDDVPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGDGVRASVQSG
EFEKRDTIPTEGRSTDEAQRGKVSSIAIPDLDGSKAEEGDILAECINSALPKGRSHKPFR
VKKIMDQVQQASMTSSGTNKNQIDTKKKKPTSPVKPMPQNTEYRTRVRKNTDSKVNVNTE
ETFSDNKDSKKQSLKNNPKDLNDKLPDNEDRVRGGFTFDSPHHYAPIEGTPYCFSRNDSL
SSLDFDDDDVDLSREKAELRKGKESKDSEAKVTCHTEPSSSQQSARKAQASTKHPVNRGP
SKPLLQEQPTFPQSSKDVPDRGAATDEKLQNFAIENTPVCFSRNSSLSSLSDVDQENNNN
EETGPVRDAEPANAQGQPGKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLRE
CISSAMPKKRRPSRLKGEGEWQSPRKVGSVLAEDLTLDLKDIQRPESEHGLSPDSENFDW
KAIQEGANSIVSSLHQAAAAAACLSRQASSDSDSILSLKSGVSLGSPFHLTPDQEEKPFT
SHKGPRILKPGEKSTLEAKKIESENKGIKGGKKVYKSLITGKIRSNSEISSQMKQPLQTN
MPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGPVATTSPRGTKPAVKS
ELSPITRQTSHISGSNKGPSRSGSRDSTPSRPTQQPLSRPMQSPGRNSISPGRNGISTPN
KLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQLSQQNLSKQTGLSKNASSIPRSESASKG
LNQMNNSNGSNKKVELSRMSSTKSSGSESDRSERPALVRQSTFIKEAPSPTLRRKLEESA
SFESLSPSSRPDSPTRSQAQTPVLSPSLPDMSLSTHPSVQAGGWRKLPPNLSPTIEYSDG
RPSKRHDIARSHSESPSRLPVNRAGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSES
SEKAKSEDEKHVNSVPGPRQMKENQVPTKGTWRKIKESEISPTNTVSQTTSSGAASGAES
KTLIYQMAPAVSRTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSISEKGNPSIKDSKDT
QGKQSVGSGSPVQTVGLENRLNSFIQVEAPEQKGTETKAGQGSPAPVAETGETCMAERTP
FSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVGSSTKKRDSKTD
STESSGAQSPKRHSGSYLVTSV
NT seq
8529 nt
NT seq
+upstream
nt +downstream
nt
atggcagcagcctcatatgatcagttgttaaagcaagttgaggccctgaagatggagaac
tcaaatcttcgacaagagctcgaagataattccaatcaccttacagaactggaaactgag
gcatctaacatgaaggaagtacttaagcagctgcagggaagtattgaagatgagactatg
acttccggacagattgatttactagagcgccttaaagaatttaacttagatagcaatttc
cccggagtgaaactacgctcgaaaatgtccctccgatcctatggaagtcgggaaggatct
gtatcaagccgttcaggagaatgcagtcctgtccccatggggtcattcccaagaagagca
tttgtaaatggaagcagagaaagcactggatacttagaagagcttgagaaagagagatca
ttactccttgctgatcttgacaaagaagaaaaggaaaaggactggtattatgctcagctt
cagaacctcacgaaaagaatagatagcctgcccttgactgagaacttttccttacagaca
gacatgacaagacggcagctggagtatgaagcacggcagatcagggccgcaatggaggag
cagcttggcacctgccaggacatggagaaacgagcacagcgaagaatagccaggattcag
caaatagagaaggacattcttcgtgtacggcagctcttacagtcccaagcggctgaagca
gagaggtcatctcagagcaagcatgaaactgcctcccatgaagctgagcggcagcttgaa
ggtcaaggagtggcagaaagcaacttggcaacttctggtagtggccagagttcagctgca
cgtgtggatcatgaaacagccggtgttttgagttctagcggcacacactctgctcctcga
aggctgacgagtcacctgggaacgaaggtggaaatggtgtattcattgttgtccatgctt
ggtactcatgataaggacgatatgtcacgaactttgctagctatgtctagctcccaagac
agctgtatatccatgcgacagtctggatgtcttcctctcctcatccagcttttacatggc
aatgacaaagactctgtgttgttgggaaattcccggggcagtaaagaggctcgggccagg
gccagtgcagccctccacaacatcattcactcacagcctgatgacaagagaggcaggcgt
gaaatccgggtccttcatcttttggaacagatacgagcttactgcgaaacctgttgggag
tggcaggaagcccatgaacaaggcatggaccaggacaaaaatccaatgccagctcctgtt
gagcatcagatctgccctgcggtgtgtgttctgatgaaactctcatttgatgaggagcac
agacatgcgatgaatgagcttggggggctgcaggctattgcagagttactgcaggtggac
tgtgagatgcacgggctcactgatgaccactacagtgtcactctacgacggtacgctgga
atggccttgacaaacctgacctttggagatgttgccaacaaggctacgctgtgttctatg
aaaggctgcatgagggcactcgtggcccagttaaaatccgaaagtgaagacttacagcag
gttattgcaagtgttttgcggaatttgtcttggcgagcagatgtaaatagcaaaaagacg
ttgagagaagttggaagtgtgaaagcgttgatggaatgtgctttggaagttaaaaaggaa
tcaactctcaaaagcgtcttgagtgccttatggaatctgtccgcacactgcactgagaat
aaggctgacatatgtgctgtggacggggcactggcatttctggttggcaccctcacttac
cggagccagacaaatacgttagccatcattgaaagtggaggtgggatattacggaatgtg
tccagcttgatagctaccaacgaagaccacagacaaatcctaagagagaacaactgccta
caaactttattacagcacttgaaatctcacagcttgacaatagtcagtaatgcatgtgga
actctgtggaatctctcagcgagaaatcctaaagaccaggaggctctgtgggacatgggg
gcggtgagcatgctcaagaacctcattcattccaagcacaaaatgatcgctatggggagc
gcagcagctttaaggaatctcatggcaaacagacctgcaaagtataaggatgccaacatc
atgtctcctggctcaagtttgccatcccttcacgttaggaaacaaaaagctctagaagca
gaattagacgctcagcatttatcagaaacctttgacaatattgacaatttaagtcccaag
gcatctcatcgcagtaagcagagacacaagcagaatctttatggtgactatgtctttgac
gccagtcgacatgatgacaataggtcagacaactttaacactggaaacatgactgttctt
tcaccatacttaaataccacagtattgcccagctcttcttcatcaaggggaagtttagac
agttctcgttctgagaaagacagaagtttggagagagaacgaggtattggcctcagcact
taccattcagcaacagaaaatccgggaacctcttccaaacggggtttgcagctctctgcc
actgcagcccagatagccaaagtgatggaagaagtgtccgccctccacacctcccaggac
gacagaagccccgcctctgccgctgagctccactgtgtggcggaggagaggactgcagca
cgaagaagctctgcgtcccacacacatccaaacacacacaacttcgctaagtcggaaagc
tcaaacaggacatgctccatgccttatgccaaggtggaatataagagatcttcaaatgac
agcttaaacagtgtcactagtagtgatggctatggtaaaaggggccagatgaagccctcg
gttgagtcctactcagaagatgatgaaggtaagttttgcagttatgggcagtatcctgcc
gacctagcccataagatacacagtgcaaatcatatggatgataatggtggggagctggac
acaccaataaactacagcctcaagtactcagatgagcagctgaactcaggaaggcagagc
ccctcacaaaatgaaaggtgggcaagacccaagcatgtgatagaagatgaaataaagcaa
aacgagcaaaggcaatcaagaagccagaacaccaattttcccgtctactctgagaacact
gatgacaaacacctcaagttccaacagcattttgggcaacaagagtgcgtttccccatat
aggtccaggggaaccaatggttcagaaacaaatcgaatgggttctagtcatgcagttaat
caaaatgtgaaccagtctttgtgtcaggaagacgactatgaagatgacaagcctaccaac
tacagtgaacgttattctgaggaagaacagcatgaagaagaagagagaccgacaaattac
agcataaagtataatgaagagaaacaccatgtggatcagcctattgattatagtctaaaa
tatgccactgacatatcttcatcccagaagccatcattttcattctcaaagactccatca
gtacagggcactaaaactgaacataactctccaagcagtgaggctgcatctgcaccttca
tctaacgccaaaaggcagagtcagctgcatccaagttcagcacaaagaaatggtcagact
ccaaaagggactgcctgcaaagtcccctccatcaaccaagagacaatgcagacttactgt
gtagaagacaccccaatatgtttctcaaggtgtagttccttatcatcgctatcatcagct
gaggatgaaataggctgtgatcagacaacacaggaggcagactctgcgaatactctgcaa
atagcagagataaaagagaatgatgtgacgcggtcagctcaagaccctgcgagtgacgtc
ccagccgtgtcccagagtactagaaccaagcccagcagactccaggcttccggcttagct
tcagaatccgccaggcataaagctgttgagttttcttcaggagccaagtctccctccaaa
agcggtgctcagacacccaaaagtcccccagaacactatgtccaggagacgccccttgta
ttcagcaggtgtacttctgtcagctccctggacagttttgagagtcgctccatcgccagc
tctgttcagagtgagccatgtagtggaatggtgagtgggattgtcagccccagtgacctt
ccagacagcccagggcagaccatgccaccaagcagaagcaagacccctccccctccccct
cccccacagccagtgcagaccaagagagaggtgccaaaaactaaggtgcctgctgccgag
cagagagagggtgggcctaagcagacggccgtgagtgcggctgtgcagagggtgcaggtc
ctcccggatgccgacactctgttacactttgccacagagagtactccagatgggttttct
tgttcctctagcctaagtgctctgagtctggatgagccctttatacagaaagatgtggaa
ttaagaataatgcctccagttcaggaaaacgacaatgggaatgaaactgaaccagaacag
cctgaagaatctaatgaaaaccaggataaagaggtagaaaagcctgactctgaaaaagac
ttattagatgattccgatgatgatgatattgaaatattagaagaatgtattatttcagcc
atgccaacaaagtcatcacgcaaagccaaaaagctagcccagactgcttcaaaattacct
cctcctgtggcaaggaaaccgagtcagctgcctgtgtacaaacttctgccgtcacagagc
aggctgcaggcacaaaaacatgtcagctttacaccaggggacgatgtgccccgagtgtac
tgtgtggaagggacgcctataaacttctccacagcaacatctctgagtgatctcacaata
gaatcccctccgaatgagctggctgctggagatggggttagagcaagtgtacagtcaggt
gagtttgaaaaacgagataccattcctacagagggcagaagtacagatgaggctcagaga
ggaaaagtctcctctatagctataccagacctggatggtagcaaagcagaggaaggagat
attcttgcagaatgcatcaattctgccctgcccaaaggaagaagccacaagcctttccga
gtgaaaaagataatggaccaagtccaacaggcatccatgacttcatccggaactaacaaa
aatcaaatagacactaagaaaaagaagcctacttcaccagtaaagcccatgccacaaaat
actgaatacagaactcgtgtgagaaagaatacagactcaaaagttaacgtaaatactgaa
gaaactttctcagacaataaagactcaaagaaacagagcttaaaaaacaaccccaaggac
ttgaatgacaagctaccggacaatgaggacagggtccggggaggctttactttcgattca
ccgcatcattacgcacccattgaagggactccttactgcttctcacgaaatgactctttg
agttctctagattttgatgatgacgatgttgacctctccagggaaaaggctgagttaaga
aagggcaaagaaagtaaggactccgaagccaaagttacctgccacacagaaccaagctca
agccaacagtcggctaggaaggcacaggctagtacaaaacatccagtgaacagagggccg
tctaaaccactgctgcaggaacaacccactttcccccagtcctctaaagacgtaccagac
agaggggcagcaactgacgaaaaactgcagaattttgctattgaaaatacaccggtttgc
ttttctcgaaattcttctctgagctcccttagtgacgttgaccaagaaaacaacaataac
gaagaaactggaccagtcagagacgctgagcctgccaacgcgcaaggacagccaggcaag
cctcaggcatctgggtatgcgcccaagtcctttcatgtggaagacacccctgtgtgcttc
tccagaaacagctctctcagctctctgagcattgattctgaggacgacctgttgcgagag
tgcataagctctgctatgccaaaaaagaggaggccttccagactcaagggtgagggtgag
tggcagagtcctaggaaagtgggcagcgtgttagccgaagatctgacactcgacttgaaa
gatatacagaggccagagtcagaacacggtttatcccccgattcagaaaatttcgactgg
aaagctattcaggaaggtgcaaactccatagtaagtagtctgcaccaagctgccgccgcc
gccgcgtgtctgtccagacaagcgtcgtcggactcagactccatcctgtccctgaagtcg
ggcgtctccctggggtcgccttttcaccttacacctgaccaagaggagaagccattcaca
agtcataaaggcccaagaattctcaaacctggggagaaaagcacattagaagcaaaaaaa
atagaatccgaaaacaaaggaatcaaaggtggaaaaaaggtttataaaagcttgattaca
ggaaagattcgatctaattcagaaatctccagccaaatgaaacaaccccttcagacaaac
atgccttcaatctcaagaggcaggacaatgattcacatcccgggagttcggaacagctcc
tcaagtacaagccctgtctctaaaaaaggcccacccctcaagactccagcctctaaaagc
cccagtgaaggtcctgtagctaccacttctcctcgtggaactaagccagcagtgaagtca
gagctgagccctattaccaggcaaacttcccacattagtgggtcaaataaggggccctct
aggtcagggtctagagactccactccctcgagacccacacagcagccattaagtaggccg
atgcagtcgccagggcggaactcgatctcccccggtagaaatggaataagcactcctaac
aaactctctcagctgcccagaacatcgtctcccagtactgcttcgaccaagtcctcgggg
tcggggaaaatgtcctacacatccccaggccggcagctgagccagcaaaacctcagcaaa
caaacaggcttgtccaagaacgccagcagcatccccagaagtgagtcagcatccaaagga
ctgaatcagatgaataacagcaatgggtctaataaaaaggtagaactttctagaatgtct
tcaactaagtcaagtggaagtgaatcagacaggtcagaaagacctgcattagtacgccag
tccactttcatcaaagaagccccaagcccaaccctaaggaggaaactggaggaatctgcc
tcatttgaatccctttctccatcttctagaccagattctcccaccaggtcccaggcacag
accccagttttaagcccttcccttcccgatatgtctctgtccacacatccatctgttcag
gcaggtggatggcgcaagctcccacctaacctcagccccactatagagtacagtgacgga
aggccctcaaagcggcatgatatcgcacgctcccattctgaaagtccgtccagactacca
gtcaaccgagcgggaacctggaagcgtgaacacagcaaacattcctcatcccttcctcga
gtgagcacttggagaagaactggaagctcatcttctattctttctgcttcttcagagtcc
agtgaaaaagcaaaaagtgaggatgaaaagcatgtgaactctgtgccaggacccagacaa
atgaaagaaaaccaggtacccacaaaaggaacatggaggaaaataaaggaaagtgaaatt
tctcccacaaacacggtttctcagaccacttcctcaggtgctgccagtggtgctgaatca
aagactctgatctatcagatggcacctgctgtttctagaacagaggacgtttgggtgaga
attgaggactgccccattaacaaccctagatctggaagatctcccacaggtaacaccccc
ccagtgattgacagcatttcagaaaagggaaatccaagcattaaagattcaaaagacacc
caaggaaaacaaagtgtgggcagtggcagtcctgtgcaaaccgtgggtctagaaaaccgc
ctgaactcctttattcaggtagaggccccggaacagaaaggaactgagactaaagcagga
cagggtagccctgcccctgtagcagagactggtgagacctgcatggcagagcgcacccct
ttcagttcaagtagctccagcaagcacagttctcccagtgggacggtcgctgccagagtg
acgccttttaattacaacccaagccctaggaaaagcagcgcagacagcacttcagcccgg
ccatctcagatccccactccggtgggcagcagcacaaagaagagagactcgaagactgac
agcactgaatctagtggagcccagagtcctaaacgccattctgggtcttacctcgtgacg
tctgtttaa
DBGET
integrated database retrieval system
