Rattus norvegicus (rat): 25290
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Entry
25290 CDS
T01003
Symbol
Alox5
Name
(RefSeq) polyunsaturated fatty acid 5-lipoxygenase
KO
K00461
arachidonate 5-lipoxygenase [EC:
1.13.11.34
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno00590
Arachidonic acid metabolism
rno01100
Metabolic pathways
rno04148
Efferocytosis
rno04664
Fc epsilon RI signaling pathway
rno04726
Serotonergic synapse
rno04913
Ovarian steroidogenesis
rno05145
Toxoplasmosis
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
25290 (Alox5)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
25290 (Alox5)
09150 Organismal Systems
09151 Immune system
04664 Fc epsilon RI signaling pathway
25290 (Alox5)
09152 Endocrine system
04913 Ovarian steroidogenesis
25290 (Alox5)
09156 Nervous system
04726 Serotonergic synapse
25290 (Alox5)
09160 Human Diseases
09174 Infectious disease: parasitic
05145 Toxoplasmosis
25290 (Alox5)
Enzymes [BR:
rno01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.34 arachidonate 5-lipoxygenase
25290 (Alox5)
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Gene cluster
GFIT
Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
25290
NCBI-ProteinID:
NP_036954
RGD:
2096
Ensembl:
ENSRNOG00000012972
UniProt:
P12527
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Position
4:complement(151203948..151251126)
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AA seq
674 aa
AA seq
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MPSYTVTVATGSQWFAGTDDYIYLSLIGSAGCSEKHLLDKAFYNDFERGAVDSYDVTVDE
ELGEIYLVKIEKRKYWLHDDWYLKYITLKTPHGDYIEFPCYRWITGEGEIVLRDGCAKLA
RDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVL
NYSKAMENLFINRFMHMFQSSWHDFADFEKIFVKISNTISERVKNHWQEDLMFGYQFLNG
CNPVLIKRCTELPKKLPVTTEMVECSLERQLSLEQEVQEGNIFIVDYELLDGIDANKTDP
CTHQFLAAPICLLYKNLANKIVPIAIQLNQTPGEKNPIFLPTDSKYDWLLAKIWVRSSDF
HIHQTITHLLRTHLVSEVFGIAMYRQLPAVHPLFKLLVAHVRFTIAINTKAREQLICEYG
LFDKANATGGGGHVQMVQRAVQDLTYSSLCFPEAIKARGMDNTEDIPYYFYRDDGLLVWE
AIQSFTTEVVSIYYEDDQVVEEDQELQDFVKDVYVYGMRGRKASGFPKSIKSREKLSEYL
TVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCW
HLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMIRFRKNLEAIVSVIAERNKNKKLPY
YYLSPDRIPNSVAI
NT seq
2025 nt
NT seq
+upstream
nt +downstream
nt
atgccttcctacactgtcaccgtagccaccggtagccagtggttcgcgggcaccgacgac
tacatttacctcagcctcattggctctgcgggctgcagtgagaagcatcttcttgacaaa
gctttctacaatgacttcgagcgcggcgcggtggactcctatgacgtcactgtggatgaa
gaactgggtgagatctacctagtcaaaatcgagaagcgcaaatactggctccatgatgac
tggtacttgaaatacatcacactgaagacaccccacggggactacatagagttcccttgt
tatcgttggatcacaggcgagggcgagattgtcctgagggatggatgtgcaaaattggcc
cgagatgaccaaatccacatcctcaagcagcacaggcggaaagaactggaaacacgtcag
aaacagtatcgatggatggagtggaaccccggcttccctttgagtattgatgctaaatgc
cacaaggatctgccccgagatatccagtttgatagtgaaaagggagtggactttgttctg
aactactcaaaagcgatggagaacctgttcatcaatcgcttcatgcacatgttccagtct
tcctggcatgactttgctgactttgagaaaatcttcgtcaaaatcagcaacactatttct
gagagagtcaagaaccactggcaagaggacctcatgtttggctaccagttcctgaatggc
tgcaacccagtactcatcaagcgctgcacagagttgcctaagaagctcccagtgaccaca
gaaatggtggagtgcagcctagagcggcagctcagtttagaacaggaagtacaggaaggg
aacattttcatcgttgattacgaactactggatggcattgatgctaacaaaactgacccc
tgtacacaccagttcctggccgcccccatctgcctgctgtataagaacctagccaacaag
attgttcccatcgccatccagctcaaccaaacccctggagagaagaacccaattttcctc
cctacggactcaaaatacgactggcttttggccaaaatctgggtgcgttcaagtgacttc
catatccatcaaacaatcacccatcttctccgcacacatctggtgtctgaggtgttcggt
attgccatgtaccgccagctgcctgctgtgcacccccttttcaagctgctggtagcccat
gtgaggttcaccattgccatcaacactaaggcccgggaacagcttatctgtgagtacggc
ctttttgacaaggccaatgccaccggaggtggtgggcacgtgcagatggtgcagagagct
gtccaggacctgacctattcctccctgtgcttcccggaggccatcaaggcccggggcatg
gacaacaccgaggacatcccctactacttctatcgtgatgatggactgctcgtgtgggaa
gctatccagtcgttcacaactgaggtggtaagcatctactatgaggatgaccaggtggtg
gaggaggaccaggaactgcaggacttcgtgaaggatgtttacgtttatggcatgcggggc
agaaaggcctcaggtttccccaagtccatcaagagcagggagaaattgtctgagtacctg
acggtggtgatcttcacagcctcggcccagcatgcagctgtaaactttggccagtatgac
tggtgctcctggatccccaacgctcctccaactatgcgggccccaccacccacggccaag
ggtgtggtcaccatcgagcagattgtggatactctaccagaccgtggccgctcatgttgg
catctaggtgcagtgtgggccttgagccagtttcaagagaatgagctgtttctgggcatg
tacccagaggagcatttcatcgagaagccagtgaaagaagccatgattcgattccgcaag
aacctggaggccatcgtcagcgtgattgccgagcgcaataagaacaaaaagctcccctac
tactacctgtcaccagacaggattccaaacagtgtagccatctaa
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