Rattus norvegicus (rat): 689883 Entry 689883            CDS       T01003                                  Gene name Setdb1 Definition (RefSeq) SET domain, bifurcated 1   KO K11421   histone-lysine N-methyltransferase SETDB1 [EC:2.1.1.43] Organism rno  Rattus norvegicus (rat) Pathway rno00310   Lysine degradation rno04550   Signaling pathways regulating pluripotency of stem cells Brite KEGG Orthology (KO) [BR:rno00001]  Metabolism   Amino acid metabolism    00310 Lysine degradation     689883 (Setdb1)  Cellular Processes   Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     689883 (Setdb1) Enzymes [BR:rno01000]  2. Transferases   2.1  Transferring one-carbon groups    2.1.1  Methyltransferases     2.1.1.43  histone-lysine N-methyltransferase      689883 (Setdb1) Chromosome [BR:rno03036]  Eukaryotic Type   Histone modification proteins    HMTs (histone methyltransferases)     HKMTs (histone lysine methyltransferases)      689883 (Setdb1)   Heterochromatin formation proteins    Other heterochromatin formation proteins     689883 (Setdb1) SSDB Motif Pfam:  SET Pre-SET MBD DUF4537 53-BP1_Tudor Other DBs NCBI-GeneID:  689883 NCBI-ProteinID:  NP_001258104 RGD:  1308370 Ensembl:  ENSRNOG00000021143 UniProt:  D4A081 LinkDB Position 2q34 AA seq 1302 aa MSSLPGCMSLAAAPAAADSAEIAELQQAVVEELGISMEELRQFIDEELEKMDCIQQRKKQ LAELETWVLQKESEVAYVDRLFDDASREVTNCESLVKDFYSKLGLQYHDSSSDDEASQPT EIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDL HKGTLGQVSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGLGKKYKVKFDNKGKS LLSGNHIAYDYHPPADKLFVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFDDG YASYVTQSELYPICRPLKKTWEDIEDSSCRDFIEEYITAYPNRPMVLLKSGQLIKTEWEG TWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASAMEKKQGGQLRTR PNMGAVRSKGPVVQYTQDLTSTGIQFKPMEPLQPIVPPAPLPMLPLSPQAGDSESLESQL AQSRKQVAKKSTSFRPGSVSSGHSSPTSPTLSENVPPGKIGMNQTYRSPSASVTSTPAPA APSGPPAPPGPLAPPGPPAPPAFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRIRP MRNEQYRGKNPLLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFET GCDFLYLEMFCLDPYVLVDRKFQPFKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYS KERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTVQATACTPGGQINPSSGYQHK RLEECLPTGVYECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSF VCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDVPSSSDSSGVDMKDQ EDGNSGSEDPEESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKESELSEVTSKDSR APDRGPPHVPITPSGSVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSRSSFKTSE GGDGRAGGGRGEAERASTSGLSFKDEGDSKQSKKEDPEDRNKMSVVTEGSQNHGHNPPMK SEGLRRPASKISMLQSQRVVTSTQSNPDDILTLSSSTESEGESGTSRKPTTGQTSATAVD SDDIQTISSGSDGDDFEDKKNLSGPTKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGE SAPVRKNTRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAF FASKRIRAGTELTWDYNYEVGSVEGKELLCCCGAIECRGRLL NT seq 3909 nt   +upstreamnt  +downstreamnt atgtcctccctccctgggtgcatgagtttggctgcagcgccagctgcggcggactctgca gagattgctgagctgcagcaggcagtggttgaagagctgggtatctctatggaggaactt cgtcagttcatcgatgaagaactggaaaagatggactgtatacagcagcgcaagaagcag ctggcagagctggagacgtgggtgctgcagaaggagtctgaggtggcttatgttgatcgg ctgtttgatgatgcatctagggaagtgactaattgtgagtctttggtgaaggatttctac tctaagctgggattacagtatcatgacagtagctctgacgatgaagcttcccagcctaca gagataatcgagattcctgatgaagatgatgatgtcctcagtattgattcaggtgatgct gggagcagaacgccaaaagatcagaagcttcgtgaagctatggctgccttaagaaaatca gctcaagatgtccagaagttcatggatgctgtgaataagaaaagcagttctcaagatcta cataaaggaaccttgggtcaggtgtctggagaactgagcaaagatggggacctgatagtc agcatgcggattctgggcaagaagaggactaagacgtggcacaaaggcaccctcattgcc atccagactgtcgggctaggaaagaaatacaaagtgaaatttgacaacaaaggaaagagt ctgctgtctgggaaccatattgcctatgattaccaccctcctgctgacaagctgtttgtg ggcagtcgagtggtggccaaatacaaagatggaaatcaggtctggctttatgctggcatt gtagctgagacccctaacgtcaagaacaagctcagatttttaattttttttgatgatggc tatgcttcctatgtcactcagtccgagctgtatcccatttgccgaccattgaaaaagact tgggaggacatagaagacagctcctgccgagacttcatagaagaatatatcactgcctat ccaaaccgcccaatggtacttctcaagagtggccagcttattaagactgagtgggaaggc acatggtggaagtctcgagttgaagaggttgatggcagcctagtcaggatcctctttctg gatgacaaaagatgtgagtggatctatcgaggctctacacgcctggaacctatgttcagt atgaagacatcctcagcctctgcaatggagaagaagcaaggggggcaactcagaacccgt cctaatatgggtgctgtgaggagcaaaggtcctgttgttcagtacactcaggatctaacg agtactggaatccagtttaagcccatggagcccctgcagcctatagtcccacctgccccg cttcccatgcttcctctttccccccaggcaggcgacagtgaaagcttagaaagccagctt gctcaatcacggaagcaagtagccaaaaagagcacatcattccgaccaggatctgtgagt tctggccattcctcccctacttcgcccacactcagtgaaaatgtaccccctgggaaaatt ggaatgaaccagacatacagatcaccttcagcctctgtaacatctaccccagcacctgca gccccttctgggcctccagcccctccagggcctcttgctcctcctggaccaccggcccct ccagctttccacggcatgttagagcgggcaccagctgagccctcctatcgtgcccctatg gagaagcttttctatttacctcatgtctgcagttacacttgtttgtcccggattagaccc atgaggaatgaacaatatcggggcaaaaaccctctactggtcccactattgtatgacttc cggaggatgacagcacgtcgcagagttaaccgcaagatgggcttccatgtaatctataag acaccctgtggtctctgccttcggacgatgcaggaaatagagcgctacctttttgagact ggctgtgacttcctgtacctggagatgttctgtttggatccatatgtccttgttgacaga aagttccagccctttaaacctttttactatattttggacatcacctatggcaaagaagat gttcccctgtcctgtgttaatgagattgacacaactcccccaccccaggtggcctacagc aaggaacgcattcctggcaagggtgttttcattaacacaggccctgaatttctggttggc tgtgactgcaaggatgggtgtcgggataaatccaagtgtgcctgccatcagctcactgtc caggccacagcctgtaccccagggggtcagatcaaccctagctccggctaccagcacaaa agactagaagagtgtctgcccacaggggtttatgagtgtaacaagcgctgcaaatgtgac ccaaacatgtgcacaaatcggttggtgcagcatggactgcaggttcgactacagctgttt aagacacagaacaagggctggggcatccgctgcttggatgacattgctaaaggctctttt gtctgcatttatgcaggcaaaatcctgacagatgactttgcagacaaagaaggcctcgag atgggtgatgagtactttgcaaatctggaccacattgaaagtgtggagaacttcaaggaa ggatatgagagtgacgtccccagctcctctgacagcagtggggtggatatgaaggaccag gaggatggcaacagtggctcagaggaccctgaggagtccaacgacgacagctccgatgac aacttctgtaaggacgaggacttcagcaccagttcagtgtggcgtagctatgcaacccgg aggcagactcggggtcagaaggagagtgaactgtctgaggtgacttcaaaggactcccgc gccccagaccgtgggcctccccacgtccctatcactccctcaggatctgtagggggttgc aatccaccttcctccgaagagacacccaagaacaaggtggcctcatggttgagctgcaat agtgtcagtgaaggtggatttgctgactctgacagccgttcctcctttaagactagtgaa ggtggagatggccgtgctgggggaggccggggagaggctgaaagagcctctacctcagga ttgagcttcaaggatgaaggagacagtaagcaatctaaaaaagaggaccctgaggaccga aacaagatgtcagtagttactgaaggctctcagaatcatggacacaatcctcccatgaag tctgaagggcttcgccgaccagctagtaaaatttctatgctccagagccagcgagttgtg acttctactcagtcaaaccctgatgatatcctaacactgtccagcagcacagaaagtgag ggggaaagtggaaccagccgaaagcccactactggtcagacttcagccacagcagttgac agtgatgacatccagaccatctcttctggctctgatggcgatgactttgaggacaagaag aacttgtcgggaccaacaaagcgtcaggtggcagtaaaatcaacccgaggctttgctctt aaatcaacccatggtattgccattaaatcaaccaacatggcttccgtggacaagggggag agtgcaccagttcgtaagaacacacgccagttctatgatggtgaagagtcttgctacatc attgatgccaaacttgaaggcaacctaggccgctacctcaatcacagttgcagccccaac ctgtttgtccagaacgtttttgtggatacccatgatcttcgcttcccttgggtggccttt tttgccagcaagagaatccgggctggaacagaactcacttgggattacaactatgaagtg ggcagtgtggaaggcaaggaactgctgtgctgctgtggagccattgaatgcagagggcgg cttctctag

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