KEGG   Shigella flexneri NCTC1 (serotype 2a): NCTC1_04092
Entry
NCTC1_04092       CDS       T03751                                 
Symbol
ilvB
Name
(GenBank) acetolactate synthase catalytic subunit,Acetolactate synthase isozyme 1 large subunit,acetolactate synthase catalytic subunit,Glyoxylate carboligase,acetolactate synthase, large subunit, biosynthetic type,Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
  KO
K01652  acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
Organism
sft  Shigella flexneri NCTC1 (serotype 2a)
Pathway
sft00290  Valine, leucine and isoleucine biosynthesis
sft00650  Butanoate metabolism
sft00660  C5-Branched dibasic acid metabolism
sft00770  Pantothenate and CoA biosynthesis
sft01100  Metabolic pathways
sft01110  Biosynthesis of secondary metabolites
sft01210  2-Oxocarboxylic acid metabolism
sft01230  Biosynthesis of amino acids
Module
sft_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
sft_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:sft00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00650 Butanoate metabolism
    NCTC1_04092 (ilvB)
   00660 C5-Branched dibasic acid metabolism
    NCTC1_04092 (ilvB)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    NCTC1_04092 (ilvB)
  09108 Metabolism of cofactors and vitamins
   00770 Pantothenate and CoA biosynthesis
    NCTC1_04092 (ilvB)
Enzymes [BR:sft01000]
 2. Transferases
  2.2  Transferring aldehyde or ketonic groups
   2.2.1  Transketolases and transaldolases
    2.2.1.6  acetolactate synthase
     NCTC1_04092 (ilvB)
SSDB
Motif
Pfam: TPP_enzyme_C TPP_enzyme_M TPP_enzyme_N DUF5107 CO_dh XFP_N
Other DBs
NCBI-ProteinID: CDX09191
UniProt: Q7UB22
LinkDB
Position
1:3812966..3814654
AA seq 562 aa
MASSGTTSTRKRFTGAEFIVHFLEQQGIKIVTGIPGGSILPVYDALSQSTQIRHILARHE
QGAGFIAQGMARTDGKPAVCMACSGPGATNLVTAIADARLDSIPLICITGQVPASMIGTD
AFQEVDTYGISIPITKHNYLVRHIEELPQVMSDAFRIAQSGRPSPVWIDIPKDVQTAVFE
IEAQPAVAEKAVAPAFSEESIRDAATMINAAKRPVLYLGGGVINAPARVRELAEKAQLPT
TMTLMALGMLPKAHPLSLGMLGMHGVRSTNYILQEADLLIVLGARFDDRAIGKTEQFCPN
AKIIHVDIDRAELGKIKQPHVAIQADVDDVLAQLIPRVEAQPRAEWHQLVADLQREFPCP
IPKACDPLSHYGLINAVAACVDDNAIITTDVGQHQMWTAQAYPLNRPRQWLTSGGLGTMG
FGLPAAIGAALANPDRKVLCFSGDGSLMMNIQEMATASENQLDVKIILMNNEALGLVHQQ
QSLFYEQGVFAATYPGKINFMQIAAGFGLETCDLNNEADPQAALQEIINRPGPALIHVRI
DAEEKVYPMVPPGAANTEMVGE
NT seq 1689 nt   +upstreamnt  +downstreamnt
atggcaagttcgggcacaacatcgacgcgtaagcgctttaccggcgcagaatttatcgtt
catttcctggaacagcagggcattaagattgtgacgggcattccgggcggttctatcctg
cctgtttacgacgccttaagccaaagcacgcaaatccgccatattctggctcgccatgaa
cagggcgcggggtttatcgctcagggaatggcgcgcaccgacggtaaaccggcggtctgt
atggcctgtagcgggccgggtgcgactaacctggtgaccgccattgctgatgcgcggctg
gactccatcccgctgatttgcatcactggtcaggttcccgcctcgatgatcggcaccgac
gccttccaagaagtggacacctacggcatctctatccccatcaccaaacacaactatctg
gtcagacatatcgaagagctcccacaggtcatgagcgatgccttccgcattgcgcaatca
ggccgccctagcccggtgtggatagacattcctaaggatgtacaaacggcggtttttgag
attgaagctcagcccgcggtggcagaaaaagccgttgcacccgcctttagcgaagaaagc
attcgtgacgcagctacaatgattaacgctgccaaacgcccggtgctttatctgggtggt
ggtgtgatcaatgcgcctgcgcgggtgcgtgaactggcggagaaagcgcaactgcctacc
accatgactttaatggcgctgggcatgctgccaaaagcgcatccgttgtcgctgggtatg
ctggggatgcacggcgtgcgcagtaccaactatattttgcaggaggcggatttgttgatt
gtgctcggtgcgcgttttgatgaccgggcgattggcaaaaccgagcagttctgtccgaat
gccaaaattattcatgtcgatatcgatcgcgcagagctgggtaaaatcaagcagccgcat
gtggcgattcaggcggatgttgatgacgtgctggcgcaattgatcccgcgggtggaagcg
caaccgcgtgcagagtggcaccagttggtagcggatttgcagcgcgaattcccgtgtcca
atcccgaaagcgtgcgatccattaagccattacggcctgatcaacgccgttgccgcctgt
gtcgatgacaatgcgattatcaccaccgatgtgggtcagcatcagatgtggaccgcgcaa
gcttatccgctcaatcgcccacgccagtggctgacctccggtgggctgggcacgatgggt
tttggcctgcctgcggcgattggcgcggcgctggcgaacccggatcgcaaagtgttgtgt
ttctccggcgacggcagcctgatgatgaatattcaggagatggcgaccgccagtgaaaat
cagctggatgtcaaaatcattctgatgaacaacgaagcgctggggctggtgcatcagcaa
cagagtctgttctacgagcaaggcgtttttgccgccacctatccgggcaaaatcaacttt
atgcagattgccgccggattcggcctcgaaacctgtgatttgaataacgaagccgatccg
caggctgcattgcaggaaatcatcaatcgccctggcccggcgctgatccatgtgcgcatt
gatgccgaagaaaaagtttacccgatggtgccgccaggtgcggcgaatactgaaatggtg
ggggaataa

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