Streptomyces parvulus: Spa2297_09025
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Entry
Spa2297_09025 CDS
T04685
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
spav
Streptomyces parvulus
Pathway
spav00010
Glycolysis / Gluconeogenesis
spav00020
Citrate cycle (TCA cycle)
spav00620
Pyruvate metabolism
spav00785
Lipoic acid metabolism
spav01100
Metabolic pathways
spav01110
Biosynthesis of secondary metabolites
spav01120
Microbial metabolism in diverse environments
spav01200
Carbon metabolism
spav01210
2-Oxocarboxylic acid metabolism
Module
spav_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
spav00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
Spa2297_09025
00020 Citrate cycle (TCA cycle)
Spa2297_09025
00620 Pyruvate metabolism
Spa2297_09025
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Spa2297_09025
Enzymes [BR:
spav01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
Spa2297_09025
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_N
DUF3135
Transket_pyr
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
ANJ07134
UniProt:
A0A191UWM7
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Position
1957479..1960181
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AA seq
900 aa
AA seq
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MTDPKAIQPSELDQLPDRDPEETAEWQASLDAVTKAAGPHRAAYLMRRTLERAEGAGLAL
PKLLETDYVNSIPTADEPAVDGDEDLEQRITAWNRWNAAAMVTRGSKHGVGGHIATFASA
AWLYETGFNHFFKGKEGDGSGDQLYVQGHASPGIYARAFLDGRLTEDHLDNFRRESGGNG
LPSYPHPRRLPWLWEFPTVSMGLGPISAIYQARFNRYLTNRGIKDLTNSHVWAFLGDGEM
DEPESTTALTLASREGLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVVKSL
WGTAWDELFQLDTNGALVRRLREVPDAQVQTYQTRDAAYIREDFFGKDPELAAMAKLLSD
DKILECFHYSRGGHEARKVYAAYKAALAHKGAPTVILAQTVKGHTLGTGFASKNANHQMK
KLSVDEFKDMRDLLGLPIKDSDFTDGVVPYGHPGADSPEVRYLQERRAALGGPAPARRVH
PVAPLPAPAEKAFASFDKGSGSQSVATTMAFVRLVKDLVRDKETGKRWVPIVPDEARTFG
MESLFPSLGIYSPKGQTYEPVDRDQLMYYKEAENGQILNEGITEAGSMADFIAASTSYAT
HGETMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLVGATAGRTTLTGEGLQHADGHSPA
IAATNPAALTYDPAFAYEVAAIVKDGLRRMYGEAAPGEDPDVFYYLTVYNEPMPQPAKPS
AAGVDEGIVKGLYRFNTAETAGLTPAANAPRIQLLGSGTAIHWALKAQRLLSEEWGVAAD
VWSATSWTELRRDAMDADAALLRGEERVPYLRRALQGAEGPVLAVSDYMRQVPDQIAQWV
EQDYSSLGADGFGLSDTRDAARRHFGVDAESIVVAALAQLARRGEVKAAAVKEARERYGL
NT seq
2703 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaccccaaagccatccagccgagcgagctcgaccagctcccggaccgcgacccg
gaggagaccgccgagtggcaggcctccctggacgccgtcaccaaggctgccgggccgcac
cgtgccgcgtacttgatgcgccgcaccctggagcgcgccgagggcgccggcctggcgctg
ccgaagctgctcgagacggactacgtcaactccatcccgaccgccgacgagcccgccgtg
gacggcgacgaggacctggagcagcggatcaccgcgtggaaccgctggaacgcggcagcc
atggtgacccgcggcagcaagcacggcgtcggcggccacatcgccaccttcgcctccgcg
gcctggctgtacgagaccggcttcaaccacttcttcaagggcaaggagggtgacggctcc
ggcgaccagctctacgtccagggccacgcctcccccggcatctacgcccgtgccttcctc
gacggccggctgaccgaggaccacctcgacaacttccgccgcgagtccggcggcaacgga
ctgccgtcctacccgcacccccgccgcctgccctggctgtgggagttccccaccgtctcc
atgggcctcgggccgatctccgcgatctaccaggcgcggttcaaccgctacctgaccaac
cgcggcatcaaggacctgaccaactcccacgtgtgggcgttcctcggcgacggcgagatg
gacgagcccgagtccaccaccgcgctgacgctcgcgtcccgcgagggcctggacaacctg
accttcgtcatcaactgcaacctgcagcgcctcgacggtccggtccgcgccaacttcaag
atcgtgcaggagctggaggcccagttccgcggcgccggctggaacgtcgtgaagtcgctg
tggggcacggcgtgggacgagctgttccagctcgacaccaacggcgccctcgtacgccgg
ctgcgcgaggtacccgacgcgcaggtgcagacgtaccagacgcgcgacgccgcctacatc
cgcgaggacttcttcggcaaggacccggagctcgccgcgatggcgaagctgctgtccgac
gacaagatcctcgagtgcttccactactcccgcggcggccacgaggcccgcaaggtctac
gccgcgtacaaggccgcgctcgcccacaagggcgcgccgaccgtgatcctggcccagacg
gtcaagggccacaccctcggcaccggcttcgcctccaagaacgccaaccaccagatgaag
aagctctcggtggacgagttcaaggacatgcgcgacctgctcggcctgccgatcaaggac
agcgacttcaccgacggcgtggtcccctacggccacccgggcgccgactcccccgaggtc
cgctacctccaggagcgccgcgcggcgctcggcggtccggccccggcccgtcgcgtgcac
ccggtcgcgccgctgcccgcgcccgccgagaaggcgttcgcctccttcgacaagggctcc
ggctcgcagagcgtggccaccaccatggccttcgtccgcctcgtcaaggacctggtccgc
gacaaggagaccggcaagcgctgggtgccgatcgtccccgacgaggcgcgcaccttcggt
atggagagcctcttcccgtccctgggcatctactcccccaagggccagacgtacgagccg
gtcgaccgcgaccagctgatgtactacaaggaggccgagaacgggcagatcctcaacgag
gggatcaccgaggccggttccatggccgacttcatcgccgcgtcgacgtcgtacgcgacg
cacggcgagacgatgatcccgttctacatcttctactcgatgttcggctggcagcgcacg
gccgaccagatgtggcagctcggcgaccagctcggccgcggcttcctggtcggtgccacg
gccggccgcaccacgctgaccggcgagggcctgcagcacgcggacggccactccccggcc
atcgcggcgaccaacccggccgcgctgacgtacgacccggcgttcgcgtacgaggtcgcg
gcgatcgtcaaggacggtctgcgccggatgtacggcgaggcggccccgggcgaggacccg
gacgtcttctactacctgaccgtctacaacgagccgatgccgcagccggccaagccgtcc
gcggccggtgtggacgagggcatcgtcaagggcctgtaccgcttcaacacggcggagacg
gcgggcctgaccccggccgcgaacgccccgcgcatccagctgctgggctccggcaccgcg
atccactgggcgctcaaggcgcagcgcctgctctccgaggagtggggcgtggccgccgac
gtgtggtccgcgacctcctggacggagctgcgccgggacgcgatggacgccgacgcggcg
ctgctgcgcggcgaggagcgggtgccgtacctccgccgggcgctccagggcgccgagggc
ccggtcctcgcggtctccgactacatgcgccaggtcccggaccagatcgcgcagtgggtc
gagcaggactactcgtcgctcggtgccgacggcttcggtctctcggacacccgcgacgcg
gcccgccggcacttcggtgtcgacgccgagtccatcgtggtcgcggctctcgcccagctc
gcccggcgcggcgaggtcaaggcggcggccgtgaaggaggcgcgcgagcgctacggcctg
tag
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