Streptococcus pyogenes MGAS6180 (serotype M28): M28_Spy0139
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Entry
M28_Spy0139 CDS
T00263
Symbol
slo
Name
(GenBank) streptolysin O
KO
K11031
thiol-activated cytolysin
Organism
spb
Streptococcus pyogenes MGAS6180 (serotype M28)
Pathway
spb02024
Quorum sensing
Brite
KEGG Orthology (KO) [BR:
spb00001
]
09140 Cellular Processes
09145 Cellular community - prokaryotes
02024 Quorum sensing
M28_Spy0139 (slo)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02042 Bacterial toxins [BR:
spb02042
]
M28_Spy0139 (slo)
Bacterial toxins [BR:
spb02042
]
Type II toxins: Membrane damaging toxins
Pore-forming toxins, Beta-pore-forming/Cholesterol-dependent
M28_Spy0139 (slo)
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Gene cluster
GFIT
Motif
Pfam:
Thiol_cytolysin
Thiol_cytolys_C
DUF6479
Motif
Other DBs
NCBI-ProteinID:
AAX71253
UniProt:
Q48VK3
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Position
156813..158537
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AA seq
574 aa
AA seq
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MKDMSNKKTFKKYSRVAGLLTAALIIGNLVTANAESNKQNTASTETTTTNEQPKPESSEL
TIEKAGQKMDDMLNSNDMIKLAPKEMPLESAEKEEKKSEDKKKSEEDHTEEINDKIYSLN
YNELEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNINTTPVDISIIDSVTDMTYPAA
LQLADKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVNDPTYANVSTAIDNLVNQWH
DNYSGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDGTLGIDFKSISKGEKKVMIAAY
KQIFYTVSANLPNNPADVFDKSVTFKELQRKGVSNEAPPLFVSNVAYGRTVFVKLETSSK
SNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAVVLGGDAAEHNKVVTKDFDVIRNVIK
DNATFSRKNPAYPISYTSVFLKNNKIAGVNNRTEYVETTSTEYTSGKINLSHRGAYVAQY
EILWDEINYDDKGKEVITKRRWDNNWYSKTSPFSTVIPLGANSRNIRIMARECTGLAWEW
WRKVIDERDVKLSKEINVNISGSTLSPYGSITYK
NT seq
1725 nt
NT seq
+upstream
nt +downstream
nt
atgaaggacatgtctaataaaaaaacatttaaaaaatacagtcgcgtcgctgggctacta
acggcagctcttatcattggtaatcttgttactgctaatgctgaatcgaacaaacaaaac
actgctagtacagaaaccacaacgacaaatgagcaaccaaaaccagaaagtagtgagcta
actatcgaaaaagcaggtcagaaaatggatgatatgcttaactctaacgatatgattaag
cttgctcccaaagaaatgccactagaatctgcagaaaaagaagaaaaaaagtcagaagac
aaaaaaaagagcgaagaagatcacactgaagaaatcaatgacaagatttattcactaaat
tataatgagcttgaagtacttgctaaaaatggtgaaaccattgaaaattttgttcctaaa
gaaggcgttaagaaagctgataaatttattgtcattgaaagaaagaaaaaaaatatcaac
actacaccagtcgatatttccattattgactctgtcactgatatgacctatccagcagcc
cttcagctggctgataaaggttttaccgaaaacaaaccagacgcggtggtcaccaagcga
aacccacaaaaaatccatattgatttaccaggtatgggagacaaagcaacggttgaggtc
aatgaccctacctatgccaatgtttcaacagctattgataatcttgttaaccaatggcat
gataattattctggtggtaatacgcttcctgccagaacacaatatactgaatcaatggta
tattctaagtcacagattgaagcagctctaaatgttaatagcaaaatcttagatggtact
ttaggcattgatttcaagtcgatttcaaaaggtgaaaagaaggtgatgattgcagcatac
aagcaaatcttttacaccgtatcagcaaaccttcctaataatcctgcggatgtgtttgat
aaatcagtgacctttaaagagttgcaacgaaaaggtgtcagcaatgaagctccgccactc
tttgtgagtaacgtagcctatggtcgaactgtttttgtcaaactagaaacaagttctaaa
agtaatgatgttgaagcggcctttagtgcagctctaaaaggaacagatgttaaaacgaat
ggaaaatactctgatatcttagaaaatagttcatttacagctgtcgttttaggaggagat
gctgcagagcacaataaggtggtcacaaaagactttgatgttattagaaacgttatcaaa
gacaatgctaccttcagtagaaaaaacccagcttatcctatttcatacaccagtgttttc
cttaaaaataataaaattgcgggtgtcaataacagaactgaatacgttgaaacaacatct
accgagtacactagtggaaaaattaacctgtctcatcgaggtgcgtatgttgctcaatat
gaaatcctttgggatgaaatcaattatgatgacaaaggaaaagaagtgattacaaaacga
cgttgggacaacaactggtatagtaagacatcaccatttagcacagttatcccactagga
gctaattcacgaaatatccgtatcatggccagagagtgcaccggcttagcttgggaatgg
tggcgaaaagtgatcgacgaaagagatgtgaaactgtctaaagaaatcaatgtcaacatc
tcaggatcaaccctgagcccatatggttcgattacttataagtag
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