Streptococcus pyogenes MGAS2096 (serotype M12): MGAS2096_Spy0824
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Entry
MGAS2096_Spy0824 CDS
T00357
Symbol
acoA
Name
(GenBank) Pyruvate dehydrogenase E1 component alpha subunit
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
spj
Streptococcus pyogenes MGAS2096 (serotype M12)
Pathway
spj00010
Glycolysis / Gluconeogenesis
spj00020
Citrate cycle (TCA cycle)
spj00620
Pyruvate metabolism
spj00785
Lipoic acid metabolism
spj01100
Metabolic pathways
spj01110
Biosynthesis of secondary metabolites
spj01120
Microbial metabolism in diverse environments
spj01200
Carbon metabolism
spj01210
2-Oxocarboxylic acid metabolism
Module
spj_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
spj00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MGAS2096_Spy0824 (acoA)
00020 Citrate cycle (TCA cycle)
MGAS2096_Spy0824 (acoA)
00620 Pyruvate metabolism
MGAS2096_Spy0824 (acoA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MGAS2096_Spy0824 (acoA)
Enzymes [BR:
spj01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MGAS2096_Spy0824 (acoA)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
Transketolase_N
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
ABF35876
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All DBs
Position
792927..793907
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AA seq
326 aa
AA seq
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MEAEMVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVGEEAANVGAVAHL
SYDDIIFSNHRGHGQSIAKDMDLNKMMAELAGKATGVSKGRGGSMHLADFEKGNYGTNGI
VGGGYALAVGAALTQQYKGTNNIAVAFSGDGATNEGSFHESVNMAATWKLPVIFFIINNR
YGISMSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYETMGKAVEHVRGGNGPAIVE
VESYRWFGHSTADAGKYRTKEEVDEWKEKDPMIKYRTYLTSEGIATDDELDAIQAQVKKE
VDDAYEFAQNSPDPELSVAFEDVWVD
NT seq
981 nt
NT seq
+upstream
nt +downstream
nt
atggaggccgaaatggtaacagtttctaaagaacaacatttggatatgttccttaaaatg
gaacgtattcgtgaatttgattcacgtattaataaactcgtccgtcgtggatttgtacaa
ggcatgactcacttctcagttggtgaagaagcagccaatgttggagcggtggctcacttg
tcttacgatgacattattttttcaaatcaccgtggacatggacaatcaatcgctaaagac
atggaccttaataaaatgatggctgagcttgctggtaaagcaactggtgtttctaaaggg
cgtggtggctcaatgcacttggctgattttgaaaaaggaaactatggtaccaatggtatc
gttggtggtggttacgctcttgcagttggtgctgccctcacccaacaatacaaaggaact
aacaatatagctgttgctttctcaggtgatggcgctactaacgaaggatcattccacgag
tctgttaatatggctgcaacatggaaacttcctgttattttcttcatcatcaacaaccgt
tatggaatttcaatgagcatcaataatgcaacaaatacaccacacttatacacacgtgca
gaagcttacggaattcctggtttctactgtgaagatggcaatgacgtgatggctgtctat
gaaacaatgggcaaagccgttgaacatgttcgtggtggaaatggcccagctattgttgag
gtagaatcataccgttggtttggtcactcgactgcagatgctggtaaataccgtactaaa
gaagaagtggatgagtggaaagaaaaagatccaatgatcaaatatcgtacttatctgaca
agcgaaggcattgccactgatgacgaattggatgctattcaagcacaagtcaaaaaagaa
gttgacgatgcttatgaatttgcacaaaacagtccagatccagaactttcagtagccttc
gaagacgtttgggttgactaa
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