KEGG   Streptococcus pneumoniae SPN034156: SPN034156_00420Help
Entry
SPN034156_00420   CDS       T02628                                 

Definition
(GenBank) D-Ala D-Ala ligase A
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
spne  Streptococcus pneumoniae SPN034156
Pathway
spne00473  D-Alanine metabolism
spne00550  Peptidoglycan biosynthesis
spne01100  Metabolic pathways
spne01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:spne00001]
 Metabolism
  Metabolism of other amino acids
   00473 D-Alanine metabolism
    SPN034156_00420
  Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    SPN034156_00420
 Human Diseases
  Drug resistance
   01502 Vancomycin resistance
    SPN034156_00420
Enzymes [BR:spne01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     SPN034156_00420
Peptidoglycan biosynthesis and degradation proteins [BR:spne01011]
 Precursor biosynthesis
  Amino acid ligase
   SPN034156_00420
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N ATP-grasp_4 CPSase_L_D2 ATP-grasp_3 RimK ATPgrasp_YheCD ATP-grasp TTL Peptidase_C23
Motif
Other DBs
NCBI-ProteinID: CCP35711
LinkDB All DBs
Position
35267..36232
Genome map
AA seq 321 aa AA seqDB search
MAIIKKIVVLYGGLSEEREVSENSAKEISKSLLTLGYDVISIDLSQDCSYEIGEIEKSER
GLNKQKVEIGSGIIDVCRKVDIVFLATHGGIGENGKLQAIFDVEKIDYTGNSFLSTAISM
DKKLSKIVASSVGIKCASNLMVDRIQANDFPIVIKPIRSGSSKGIKIFQNKKQFDIYYKE
HPELGSVFVEKYIKGREFSVGILGETVLPVIEIKVKNGFYDYNNKYTVGAAEEVVPAKIS
EKLTHTLQKSAYKIHKALGFNVYSRTDFIVDEKGDVYFIESNSLPGMTKTSLLPQEAKAA
GIDFPNLCERIIELSREIRSQ
NT seq 966 nt NT seq  +upstreamnt  +downstreamnt
atggctattattaaaaaaattgttgtactatatggtggccttagcgaagagagggaggtg
tcagaaaattctgcaaaggaaattagtaaaagtctattaacattggggtatgatgtgatt
tctatagatttatctcaagactgttcgtacgagataggagaaattgaaaaaagtgagcgc
ggattaaataaacaaaaagttgagattggttcgggtattattgatgtttgtagaaaggtt
gatatagttttcttagcaactcatggtggaataggtgagaatgggaaactacaggctatt
tttgatgtagaaaaaatagactatacaggaaattcgtttcttagtacagctattagcatg
gataaaaaattatcaaaaatagtggctagttctgttggaataaaatgtgcttcgaacttg
atggttgatagaattcaggcaaatgattttcctattgttataaagccaattagaagtggt
tcaagtaaaggtattaagatatttcaaaataaaaaacaatttgacatttattataaagag
catcctgaacttggttcagtctttgtagaaaagtatattaaggggagagaattttcggta
ggtattttaggtgaaactgttttaccggttattgaaataaaagtaaaaaatggtttttat
gattataataacaagtacactgttggtgcagctgaagaagtcgttcccgcaaaaatatct
gaaaagttaactcataccttacaaaaatccgcatataaaatacataaggctcttggattt
aatgtttattcacgtactgattttattgtagatgagaagggggatgtatattttattgaa
tcaaatagtttaccaggtatgactaaaacaagtttattaccacaggaagcgaaagcagct
ggtatagatttcccaaacctatgtgaacgtattattgagctgagtagggaaattagatct
caatag

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