Streptococcus pyogenes HSC5 (serotype M14): L897_00280
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Entry
L897_00280 CDS
T02743
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
spyh
Streptococcus pyogenes HSC5 (serotype M14)
Pathway
spyh00230
Purine metabolism
spyh01100
Metabolic pathways
spyh01110
Biosynthesis of secondary metabolites
Module
spyh_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
spyh00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
L897_00280
Enzymes [BR:
spyh01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
L897_00280
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
GATase_3
DJ-1_PfpI
GATase
Svf1_C
Motif
Other DBs
NCBI-ProteinID:
AGQ26969
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All DBs
Position
36823..40596
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AA seq
1257 aa
AA seq
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MSSYFPVAPLSDLVSYMNKRIFVEKKADFGIKSASLVKELTHNLQLTSLKDLRIVQVYDV
FNLAEDLLARAEKHIFSEQVTDRLLTEAEITAELDKVAFFAIEALPGQFDQRAASSQEAL
LLFGSDSQVKVNTAQLYLVNKDITEAELEAVKNYLLNPVDSRFKDITLPLEEQAFSVSDK
TIPNLDFFETYQADDFATYKAEQGLAMEVDDLLFIQDYFKSIGRVPTETELKVLDTYWSD
HCRHTTFETELKNIDFSASKFQKQLQTTYDKYIAMRDELGRSEKPQTLMDMATIFGRYER
ANGRLDDMEVSDEINACSVEIEVDVDDVKEPWLLMFKNETHNHPTEIEPFGGAATCIGGA
IRDPLSGRSYVYQAMRISGAGDITTPIAETRAGKLPQQVISKTAAHGYSSYGNQIGLATT
YVREYFHPGFVAKRMELGAVVGAAPKENVVREKPEAGDVVILLGGKTGRDGVGGATGSSK
VQTVESVETAGAEVQKGNAIEERKIQRLFRDGNVTRLIKKSNDFGAGGVCVAIGELADGL
EIDLDKVPLKYQGLNGTEIAISESQERMSVVVRPSDVDAFIAACNKENIDAVVVATVTEK
PNLVMTWNGEIIVDLERRFLDTNGVRVVVDAKVVDKDLTVPEARTTSAETLEADTLKVLS
DLNHASQKGLQTIFDSSVGRSTVNHPIGGRYQITPTESSVQKLPVQHGVTTTASVMAQGY
NPYIAEWSPYHGAAYAVIEATARLVATGADWSRARFSYQEYFERMDKQAERFGQPVSALL
GSIEAQIQLGLPSIGGKDSMSGTFEDLTVPPTLVAFGVTTADSRKVLSPEFKAAGENIYY
IPGQAISEDIDFDLIKDNFSQFEAIQAQHKITAASAAKYGGVLESLALMTFGNRIGASVE
IAELDSSLTAQLGGFVFTSAEEIADAVKIGQTQADFTVTVNGNDLAGASLLAAFEGKLEE
VYPTEFEQTDVLEEVPAVVSDTVIKAKETIEKPVVYIPVFPGTNSEYDSAKAFEQVGASV
NLVPFVTLNEVAIAESVDTMVANIAKANIIFFAGGFSAADEPDGSAKFIVNILLNEKVRA
AIDSFIEKGGLIIGICNGFQALVKSGLLPYGNFEEAGETSPTLFYNDANQHVAKMVETRI
ANTNSPWLAGVEVGDIHAIPVSHGEGKFVVSASEFAELRDNGQIWSQYVDFDGQPSMDSK
YNPNGSVNAIEGITSKNGQIIGKMGHSERWEDGLFQNIPGNKDQTLFASAVKYFTGK
NT seq
3774 nt
NT seq
+upstream
nt +downstream
nt
atgtcctcctattttccagtcgctcccttgtcggatttggtatcttatatgaataaacgt
atttttgttgagaaaaaggctgactttggcattaaatcggctagccttgtgaaagagttg
acacataatctacaactgacttctttgaaggacttgcgtattgtgcaggtctatgatgtc
ttcaatttggctgaggatttactggcgcgtgctgagaagcatattttctctgagcaggtg
acagaccgtcttttgacggaagctgaaatcactgcggagcttgataaggttgccttcttt
gccattgaggcgcttccaggtcaatttgaccaacgtgctgctagttcgcaagaagctttg
ctattatttggaagtgacagtcaggttaaggtcaatacagcccagctatacttggtcaat
aaggatattacagaagcagagcttgaagccgttaagaactatcttttgaaccctgttgat
tcgcgtttcaaggacattactttgccgcttgaagagcaggctttctctgtgtctgataag
acgatccctaatcttgatttctttgaaacttatcaagctgacgattttgcgacttataag
gcagagcagggcttggctatggaggtcgatgaccttctcttcatccaagattatttcaaa
tcaatcggacgtgtgccaactgagactgagttgaaagttttggatacttactggtcagac
cactgccgtcacacaacctttgaaactgaattgaagaacattgatttttcagcttctaaa
ttccaaaaacaattgcagacgacttatgacaaatatatcgccatgcgtgatgagcttggc
cgttctgaaaagccacaaacacttatggatatggcgactatctttggtcgttatgagcgt
gccaacggtcgtctggacgatatggaagtctcagatgaaatcaatgcctgctcagttgag
attgaagtagatgttgatgatgtgaaagagccttggctcctcatgtttaagaacgagact
cacaatcacccaacagaaattgagccattcggtggagcggcgacttgtatcggtggtgct
attcgtgacccattgtcaggacgttcatacgtttatcaggctatgcgtatttcaggcgca
ggcgatatcacgactccgattgcggaaacacgtgctggtaaattgccacaacaagttatt
tctaaaactgcggcgcacggctattcttcatatggtaaccaaattgggcttgcgacaact
tatgtgcgcgagtacttccaccctggcttcgtagccaaacgtatggagcttggagctgtg
gttggtgctgcacctaaggaaaatgtggttcgtgaaaaaccagaagcaggcgatgtggtc
atcttgctcggtggtaaaacaggtcgtgatggtgtcggtggtgcgacaggttcatctaag
gttcaaacggttgaatctgtggaaacagctggcgcagaggtacaaaaagggaatgccatt
gaagaacgtaagattcaacgtcttttccgtgatggcaatgtcactcgtcttattaagaaa
tcaaatgacttcggtgcaggtggtgtctgtgttgccatcggtgaattggctgacggtctt
gaaatcgatttggacaaggtgcctcttaaataccaaggtcttaatggtactgaaattgca
atctcagaatctcaagagcgtatgtcagtcgttgttcgtccaagtgatgtggatgccttc
atcgcagcctgcaacaaggaaaatatcgatgcagtcgttgttgcgaccgttactgaaaaa
ccaaatcttgtcatgacttggaatggcgaaatcatcgttgatttggaacgccgtttcctt
gataccaatggtgtccgtgtcgttgttgatgctaaagtcgttgacaaggacttgacagtt
ccagaagcacgcacaacatcagcagagacacttgaagcagatacgcttaaggtcttgtct
gacctcaaccacgctagtcaaaaaggtcttcaaactatctttgactcatctgttggtcgt
tcaaccgttaaccacccaatcggtggtcgttaccaaatcacaccgacagaaagttctgtt
caaaaattgccagttcaacatggtgtgacaacaactgcatctgttatggctcaaggttac
aatccttatattgcagagtggtcaccttatcacggtgctgcctatgctgtcattgaagcg
acagctcgcttggtagcaacgggtgctgactggtctcgtgcacgtttctcttaccaagag
tactttgagcgtatggataaacaggcagagcgttttggtcagccagtatcagctcttctt
ggttctattgaggctcagattcaacttggtttgccatcaatcggcggtaaggactctatg
tctggtactttcgaagacttgacagtaccaccaaccttggtagctttcggcgtgacaaca
gcggacagccgcaaggttctctctcctgagtttaaagcggctggcgaaaacatttactat
atcccaggtcaagctatttcagaagatattgattttgaccttatcaaggataactttagc
cagtttgaagctattcaagctcaacataagattacagctgcctcagccgctaaatacggt
ggtgtcctagaaagtcttgctctcatgacttttggtaaccgtatcggtgcttctgttgaa
attgcagagcttgacagcagcttgacagctcaactcggaggttttgtctttacatcagct
gaggaaattgctgacgcggtgaaaatcggtcaaactcaggcagactttacagtcactgtc
aatggaaatgacctagctggcgctagccttctagcagccttcgaaggcaaattggaagag
gtttacccaacagaatttgaacagacagatgttcttgaagaagttcctgctgtggtatca
gatactgttatcaaggctaaggaaacaattgaaaaaccagtggtttacattccagtcttc
cctggtaccaactcagaatacgattcagctaaggcctttgaacaggttggagctagtgtc
aacttggtaccatttgtaaccttgaatgaggttgctattgctgagtcagttgacactatg
gttgctaatattgctaaggcaaatatcatcttctttgctggaggtttctcagcagcggat
gaaccagatgggtctgctaagtttatcgtcaatatcttgcttaacgagaaggtccgcgca
gctattgacagcttcatcgaaaaaggtggccttatcatcggtatctgtaatggtttccaa
gcccttgttaaatcaggtcttcttccatacggaaacttcgaggaagctggtgagacaagt
ccaactctcttctataacgatgctaatcagcatgttgccaagatggttgagactcgtatc
gcaaataccaactcaccttggttggcaggagttgaggtcggcgatattcatgccattcca
gtttcacatggtgaaggtaaatttgttgtcagcgcttctgaatttgcagagctaagagac
aatggtcaaatctggagccaatatgtggactttgacggacaaccatctatggattctaaa
tacaatccaaatggctctgtcaatgccatcgaagggattaccagcaagaatggtcaaatc
atcggtaagatgggacactcagaacgctgggaagacggactcttccaaaatatccctggt
aacaaagaccaaaccctctttgcaagtgctgtaaaatactttacagggaagtaa
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