KEGG   Serratia sp. AS12: SerAS12_1336
Entry
SerAS12_1336      CDS       T01502                                 
Name
(GenBank) D-alanine--D-alanine ligase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
srs  Serratia sp. AS12
Pathway
srs00470  D-Amino acid metabolism
srs00550  Peptidoglycan biosynthesis
srs01100  Metabolic pathways
srs01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:srs00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    SerAS12_1336
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    SerAS12_1336
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    SerAS12_1336
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:srs01011]
    SerAS12_1336
Enzymes [BR:srs01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     SerAS12_1336
Peptidoglycan biosynthesis and degradation proteins [BR:srs01011]
 Precursor biosynthesis
  Amino acid ligase
   SerAS12_1336
SSDB
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N ATP-grasp CPSase_L_D2 ATP-grasp_4 ATPgrasp_ST RimK
Other DBs
NCBI-ProteinID: AEF49426
LinkDB
Position
1456550..1457653
AA seq 367 aa
MTKLRVGVIFGGKSAEHEVSLQSAKNIVDAIDKEKFDVTLLGIDKQGQWHINDASNYLLN
AENPALIALNRSNKNVALIPGQEKQQLIEASSAGALGQLDVVFPIVHGTLGEDGSLQGLL
RMANMPFVGAGVLGSAVSMDKDVTKRLLRDAGLAVAPFVTLTRTNRSKYGFEQLSERLGL
PLFIKPANQGSSVGVSKVQDRAGFDAALALAFSFDHKVLVESAIVGREIECAVLGNDEPQ
ASLCGEIVLSDAFYSYDTKYINEQGAKVVVPAEIAPEVSDKIRDVALKAFRALECFGLAR
VDVFLTPDNNVVINEINTLPGFTNISMYPKLWAASGVSYSELITRLIELALERHQQDRAL
NSSVFER
NT seq 1104 nt   +upstreamnt  +downstreamnt
gtgactaaattacgggttggggtgatctttggcggtaaatcggctgagcatgaagtgtcg
ctgcagtcggcaaaaaacattgtggacgctatcgacaaagagaagtttgacgtcacgctg
ctggggatcgacaagcaggggcaatggcacattaacgatgcctccaattacctgttgaat
gcggaaaacccggcgctgatcgcgctgaaccgctcaaataaaaatgtggcgctgatcccc
ggtcaggagaaacagcaactgattgaggcgagcagcgccggcgcactgggccagctcgac
gtggtattcccgatcgtgcatggcacgctgggcgaggacggttcattgcaagggctgctg
cggatggccaatatgccgttcgtcggcgccggtgtgttgggctcggcggtgagcatggac
aaagacgtcaccaaacgcctgctgcgcgatgccgggctggcggttgccccctttgtcacc
ctgacgcgcaccaatcgcagcaaatacggtttcgagcagcttagcgagcgtttgggcctg
ccgttgtttatcaaaccggctaaccagggctcttcggtgggcgtcagcaaggtgcaggat
cgggccggctttgacgcagctctggcgctggcgttcagcttcgatcacaaggtgctggtg
gagtcggcgattgtcggccgtgagattgagtgcgcggtgttgggcaatgacgagccgcag
gccagcctgtgcggtgaaatcgtgctgagcgatgctttctactcctacgacaccaaatac
atcaatgagcagggcgcgaaggtagtggtgccggcggagatcgcaccggaagtcagcgac
aaaatccgcgacgtggcgctaaaagcgttccgggcgctggaatgctttggcctggcgcgc
gttgacgtgttcctgacgccggacaacaacgtggtgattaacgaaatcaacacgctgccg
ggcttcaccaatatcagcatgtaccccaaactgtgggccgccagcggcgtcagctacagt
gagctgattacccggttgatcgagctggcgctggagcgccatcagcaagatcgcgcgctg
aacagctcggtgttcgagcggtaa

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