Serratia sp. AS12: SerAS12_1336
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Entry
SerAS12_1336 CDS
T01502
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
srs
Serratia sp. AS12
Pathway
srs00470
D-Amino acid metabolism
srs00550
Peptidoglycan biosynthesis
srs01100
Metabolic pathways
srs01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
srs00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
SerAS12_1336
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SerAS12_1336
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SerAS12_1336
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
srs01011
]
SerAS12_1336
Enzymes [BR:
srs01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
SerAS12_1336
Peptidoglycan biosynthesis and degradation proteins [BR:
srs01011
]
Precursor biosynthesis
Amino acid ligase
SerAS12_1336
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Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
CPSase_L_D2
ATP-grasp_4
ATPgrasp_ST
RimK
Motif
Other DBs
NCBI-ProteinID:
AEF49426
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All DBs
Position
1456550..1457653
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AA seq
367 aa
AA seq
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MTKLRVGVIFGGKSAEHEVSLQSAKNIVDAIDKEKFDVTLLGIDKQGQWHINDASNYLLN
AENPALIALNRSNKNVALIPGQEKQQLIEASSAGALGQLDVVFPIVHGTLGEDGSLQGLL
RMANMPFVGAGVLGSAVSMDKDVTKRLLRDAGLAVAPFVTLTRTNRSKYGFEQLSERLGL
PLFIKPANQGSSVGVSKVQDRAGFDAALALAFSFDHKVLVESAIVGREIECAVLGNDEPQ
ASLCGEIVLSDAFYSYDTKYINEQGAKVVVPAEIAPEVSDKIRDVALKAFRALECFGLAR
VDVFLTPDNNVVINEINTLPGFTNISMYPKLWAASGVSYSELITRLIELALERHQQDRAL
NSSVFER
NT seq
1104 nt
NT seq
+upstream
nt +downstream
nt
gtgactaaattacgggttggggtgatctttggcggtaaatcggctgagcatgaagtgtcg
ctgcagtcggcaaaaaacattgtggacgctatcgacaaagagaagtttgacgtcacgctg
ctggggatcgacaagcaggggcaatggcacattaacgatgcctccaattacctgttgaat
gcggaaaacccggcgctgatcgcgctgaaccgctcaaataaaaatgtggcgctgatcccc
ggtcaggagaaacagcaactgattgaggcgagcagcgccggcgcactgggccagctcgac
gtggtattcccgatcgtgcatggcacgctgggcgaggacggttcattgcaagggctgctg
cggatggccaatatgccgttcgtcggcgccggtgtgttgggctcggcggtgagcatggac
aaagacgtcaccaaacgcctgctgcgcgatgccgggctggcggttgccccctttgtcacc
ctgacgcgcaccaatcgcagcaaatacggtttcgagcagcttagcgagcgtttgggcctg
ccgttgtttatcaaaccggctaaccagggctcttcggtgggcgtcagcaaggtgcaggat
cgggccggctttgacgcagctctggcgctggcgttcagcttcgatcacaaggtgctggtg
gagtcggcgattgtcggccgtgagattgagtgcgcggtgttgggcaatgacgagccgcag
gccagcctgtgcggtgaaatcgtgctgagcgatgctttctactcctacgacaccaaatac
atcaatgagcagggcgcgaaggtagtggtgccggcggagatcgcaccggaagtcagcgac
aaaatccgcgacgtggcgctaaaagcgttccgggcgctggaatgctttggcctggcgcgc
gttgacgtgttcctgacgccggacaacaacgtggtgattaacgaaatcaacacgctgccg
ggcttcaccaatatcagcatgtaccccaaactgtgggccgccagcggcgtcagctacagt
gagctgattacccggttgatcgagctggcgctggagcgccatcagcaagatcgcgcgctg
aacagctcggtgttcgagcggtaa
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