KEGG   Sus scrofa (pig): 100158154Help
Entry
100158154         CDS       T01009                                 

Gene name
PKM, PK-S
Definition
pyruvate kinase, muscle
Orthology
K00873  
pyruvate kinase [EC:2.7.1.40]
Organism
ssc  Sus scrofa (pig)
Pathway
Glycolysis / Gluconeogenesis
Purine metabolism
Pyruvate metabolism
Metabolic pathways
Carbon metabolism
Biosynthesis of amino acids
Type II diabetes mellitus
Viral carcinogenesis
Central carbon metabolism in cancer
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Glycolysis, core module involving three-carbon compounds
Adenine ribonucleotide biosynthesis, IMP => ADP,ATP
Guanine ribonucleotide biosynthesis IMP => GDP,GTP
Brite
KEGG Orthology (KO) [BR:ssc00001]
 Metabolism
  Overview
   01200 Carbon metabolism
    100158154 (PKM)
   01230 Biosynthesis of amino acids
    100158154 (PKM)
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    100158154 (PKM)
   00620 Pyruvate metabolism
    100158154 (PKM)
  Nucleotide metabolism
   00230 Purine metabolism
    100158154 (PKM)
 Human Diseases
  Cancers
   05230 Central carbon metabolism in cancer
    100158154 (PKM)
   05203 Viral carcinogenesis
    100158154 (PKM)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100158154 (PKM)
Enzymes [BR:ssc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.40  pyruvate kinase
     100158154 (PKM)
Exosome [BR:ssc04147]
 Exosomal proteins
  Proteins found in most exosomes
   100158154 (PKM)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
LinkDB All DBs
Position
7
AA seq 531 aa AA seqDB search
MPKPHSDAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVET
LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRAATESFASDPILYRPVAVALDTKGPEIR
TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENVLWLDYKNICKVVDVGSKVYVDDGL
ISLLVKQKGPDFLVTEVENGGFLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV
FASFIRKAADVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIE
IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM
LSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEAAAVGAVEAS
FKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDPVQE
AWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP
NT seq 1596 nt NT seq  +upstreamnt  +downstreamnt
atgccgaagccccacagtgatgccgggaccgccttcattcagacccagcagctgcacgcg
gccatggctgacacgttcctggagcacatgtgccgcctggacattgactcgccacccatc
acggcccggaacaccggcatcatctgtaccatcggcccagcttcccgatcagtggagaca
ctgaaggagatgattaagtctggaatgaacgtggctcgtttgaacttctctcacggaact
catgagtaccatgcagagaccatcaagaacgtgcgtgcggctacagaaagctttgcttca
gatcccattctctaccggccagtggctgtggccctggacactaaaggacctgagatccga
accgggctcatcaagggcagcggcactgctgaggtggagctcaagaaaggagccacgctc
aagatcaccctggataatgcctacatggaaaagtgtgacgagaatgtcctgtggctggac
tataagaacatctgcaaggtggtggatgtgggcagcaaggtctacgtggatgatggactt
atttctttgctggtgaagcagaaaggtcctgacttcctggtgacggaggtggagaacggc
ggcttcctgggcagcaagaaaggtgtgaaccttcctggagctgctgtggacctgcctgcc
gtgtccgagaaggacatccaggatctgaagtttggggtggagcaggacgtggatatggtg
ttcgcatctttcatccgtaaggcggccgacgtccatgaagtcaggaaggtcctgggagag
aaaggaaagaacatcaagataatcagcaaaatcgagaatcacgagggagttcggagattt
gatgagatcctagaagccagcgatggtatcatggtggctcgtggtgatctaggcattgag
attcctgcagagaaggtcttccttgcccagaagatgatgattgggcggtgcaaccgagct
gggaagcctgtcatctgtgccacgcagatgctggagagcatgatcaagaagccccgtccc
acccgggctgagggcagtgatgtggccaatgcagtcttggatggagctgactgcatcatg
ctgtctggagagacggccaaaggggactaccccctggaggctgttcgcatgcagcacctg
attgcccgtgaggcagaggccgccatctaccatttgcaattatttgaggagctccgccgc
ctggcgcccattaccagcgaccctaccgaagctgccgccgtgggcgccgtggaggcctcc
ttcaagtgctgcagtggggccataatcgtcctcaccaagtctggcaggtctgcacatcag
gtggctaggtaccgcccccgagcccccatcattgctgtgacccggaatcaccagacagct
cgccaggcccacctgtaccgcggcatcttccccgtggtgtgtaaggacccagtgcaggag
gcctgggccgaggacgtggacctccgggtgaacttggccatgaatgttggcaaagcccga
ggcttcttcaagaagggagatgtggtcattgtgctgaccgggtggcgccctggttccggc
ttcaccaacaccatgcgcgtagtgcctgtgccgtga

DBGET integrated database retrieval system