KEGG T01009: 100158154

Sus scrofa (pig): 100158154

Entry

100158154 CDS T01009

Gene name

PKM, PK-S, PKM2

Definition

pyruvate kinase, muscle

Orthology

K00873

pyruvate kinase [EC:2.7.1.40]

Organism

ssc Sus scrofa (pig)

Pathway

ssc00010	Glycolysis / Gluconeogenesis
ssc00230	Purine metabolism
ssc00620	Pyruvate metabolism
ssc01100	Metabolic pathways
ssc01230	Biosynthesis of amino acids
ssc04930	Type II diabetes mellitus
ssc05203	Viral carcinogenesis

Module

ssc_M00001	Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
ssc_M00002	Glycolysis, core module involving three-carbon compounds
ssc_M00049	Adenine ribonucleotide biosynthesis, IMP => ADP,ATP
ssc_M00050	Guanine ribonucleotide biosynthesis IMP => GDP,GTP

Class

Metabolism; Carbohydrate metabolism; Glycolysis / Gluconeogenesis [PATH:ssc00010]
Metabolism; Carbohydrate metabolism; Pyruvate metabolism [PATH:ssc00620]
Metabolism; Nucleotide metabolism; Purine metabolism [PATH:ssc00230]
Human Diseases; Cancers; Viral carcinogenesis [PATH:ssc05203]
Human Diseases; Endocrine and metabolic diseases; Type II diabetes mellitus [PATH:ssc04930]

SSDB

Motif

Pfam:

PK PK_C HpcH_HpaI IMPDH

Other DBs

NCBI-GI:

194038728

NCBI-GeneID:

100158154

Ensembl:

ENSSSCG00000001930

Position

AA seq 531 aa
MPKPHSDAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVET
LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRAATESFASDPILYRPVAVALDTKGPEIR
TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENVLWLDYKNICKVVDVGSKVYVDDGL
ISLLVKQKGPDFLVTEVENGGFLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV
FASFIRKAADVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIE
IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM
LSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEAAAVGAVEAS
FKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDPVQE
AWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP

NT seq 1596 nt +upstreamnt +downstreamnt
atgccgaagccccacagtgatgccgggaccgccttcattcagacccagcagctgcacgcg
gccatggctgacacgttcctggagcacatgtgccgcctggacattgactcgccacccatc
acggcccggaacaccggcatcatctgtaccatcggcccagcttcccgatcagtggagaca
ctgaaggagatgattaagtctggaatgaacgtggctcgtttgaacttctctcacggaact
catgagtaccatgcagagaccatcaagaacgtgcgtgcggctacagaaagctttgcttca
gatcccattctctaccggccagtggctgtggccctggacactaaaggacctgagatccga
accgggctcatcaagggcagcggcactgctgaggtggagctcaagaaaggagccacgctc
aagatcaccctggataatgcctacatggaaaagtgtgacgagaatgtcctgtggctggac
tataagaacatctgcaaggtggtggatgtgggcagcaaggtctacgtggatgatggactt
atttctttgctggtgaagcagaaaggtcctgacttcctggtgacggaggtggagaacggc
ggcttcctgggcagcaagaaaggtgtgaaccttcctggagctgctgtggacctgcctgcc
gtgtccgagaaggacatccaggatctgaagtttggggtggagcaggacgtggatatggtg
ttcgcatctttcatccgtaaggcggccgacgtccatgaagtcaggaaggtcctgggagag
aaaggaaagaacatcaagataatcagcaaaatcgagaatcacgagggagttcggagattt
gatgagatcctagaagccagcgatggtatcatggtggctcgtggtgatctaggcattgag
attcctgcagagaaggtcttccttgcccagaagatgatgattgggcggtgcaaccgagct
gggaagcctgtcatctgtgccacgcagatgctggagagcatgatcaagaagccccgtccc
acccgggctgagggcagtgatgtggccaatgcagtcttggatggagctgactgcatcatg
ctgtctggagagacggccaaaggggactaccccctggaggctgttcgcatgcagcacctg
attgcccgtgaggcagaggccgccatctaccatttgcaattatttgaggagctccgccgc
ctggcgcccattaccagcgaccctaccgaagctgccgccgtgggcgccgtggaggcctcc
ttcaagtgctgcagtggggccataatcgtcctcaccaagtctggcaggtctgcacatcag
gtggctaggtaccgcccccgagcccccatcattgctgtgacccggaatcaccagacagct
cgccaggcccacctgtaccgcggcatcttccccgtggtgtgtaaggacccagtgcaggag
gcctgggccgaggacgtggacctccgggtgaacttggccatgaatgttggcaaagcccga
ggcttcttcaagaagggagatgtggtcattgtgctgaccgggtggcgccctggttccggc
ttcaccaacaccatgcgcgtagtgcctgtgccgtga

All links

Pathway (11)   
   KEGG PATHWAY (7)   
   KEGG MODULE (4)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (6)   
   KEGG ENZYME (1)   
   KEGG REACTION (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   UniGene (1)   
   ENSEMBL-SSC (1)   
   OC (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (8)   
   RefSeq(nuc) (2)   
   GenBank (3)   
   EMBL (3)   
Protein domain (4)   
   Pfam (4)   
All databases (50)   

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