Thermus thermophilus JL-18: TtJL18_0841
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Entry
TtJL18_0841 CDS
T02009
Name
(GenBank) 2-isopropylmalate synthase, bacterial type
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
ttl
Thermus thermophilus JL-18
Pathway
ttl00290
Valine, leucine and isoleucine biosynthesis
ttl00620
Pyruvate metabolism
ttl01100
Metabolic pathways
ttl01110
Biosynthesis of secondary metabolites
ttl01210
2-Oxocarboxylic acid metabolism
ttl01230
Biosynthesis of amino acids
Module
ttl_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ttl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
TtJL18_0841
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
TtJL18_0841
Enzymes [BR:
ttl01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
TtJL18_0841
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
TipAS
Motif
Other DBs
NCBI-ProteinID:
AFH38743
UniProt:
H9ZQY3
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Position
761749..763311
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AA seq
520 aa
AA seq
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MEKERHIRIFDTTLRDGEQSPGVALSLDQKLEIAQALARLNVDIIEAGFPVSGPLEFEAV
RRIATEVKGPIIAALARTHTLDIDQAAKALEKAEKPRIHVFTSASKVHLQYMLRKTEEEV
LEMADRMVRYARRYVDDVEFSAQDVMRADWEFVKRLYEVAIEAGATTINIPDTTGYGTPQ
EYGALIRRIRDEVVRGRDVIISTHTHDDLGLATANALAGVENGAGQIECTVNGIGERAGN
CALEEVVMALYVRRDWYKAYTQINTREIYRVSRLVERYTGMPVPPNKAIVGDNAFAHESG
IHQDGVIKHRATYEIMDAELIGRRPAVLVLGKHSGRAAFKKALEDLGYKDLSEEEIKKLF
ARFKEIAEKKGPLSAEELQALVESEREPTSHFFQLERVQFFSGSGLLPTATVQVKTPDGE
RLATHTGDGPVDAVFKAIQEAIGLRPELELYRVEAITGSTEALGQVTVRLRLGELQAVGV
GVSPDIIEASALAFLDAAGKLASGRATRHPPSIEEVHRGV
NT seq
1563 nt
NT seq
+upstream
nt +downstream
nt
atggagaaggaacggcacatccggatctttgacaccacgctcagggacggggagcaaagc
ccaggggtggccctctccctggaccagaagctggagatcgcccaggccctcgcccggctc
aacgtggacatcattgaggcgggcttccccgtatcggggcctttggagtttgaggcggtg
cgccgcatcgccaccgaggtcaaaggtcccatcatcgccgccctcgcccgcacccacacc
ctggacattgaccaggcggccaaggccctggagaaggcggagaagcccaggatccacgtc
ttcacctccgcctccaaggtccacctgcagtacatgctgaggaagacggaggaggaggtc
ctggagatggcggatagaatggtccgctacgccaggaggtacgtggacgacgtggagttc
tccgcccaggacgtgatgcgggcggactgggagttcgtcaagcggctttacgaggtggcc
attgaggccggggccaccaccatcaacatccccgacaccacgggctacggcacgccccag
gagtacggggccctgatccgcaggatccgggacgaggtggtgcggggccgggacgtgatc
atctccacccacacccacgacgacctgggcctggccaccgccaacgccctggcgggcgtg
gagaacggggcgggccagattgagtgcaccgtcaacggcatcggggagcgggcggggaac
tgcgccctggaggaggtggtcatggccctctacgtccgccgggactggtacaaggcctac
acgcagatcaacacccgggagatctaccgggtgagccgcctggtggagcgctacaccggg
atgcccgtcccccccaacaaggccatcgtgggggacaacgccttcgcgcacgagtccggc
atccaccaggacggggtcatcaagcaccgggccacctacgagattatggacgccgagctc
atcgggaggcggcccgccgttttggtcctcggcaagcactcgggccgggcggccttcaag
aaggccctcgaggacctgggctacaaggacctctccgaggaggagataaagaagctcttc
gcccggttcaaggagatcgccgaaaagaaggggcccctttccgccgaagagctccaggcc
ctggtggaaagcgagcgggagcccacctcccacttcttccagctggagcgggtccagttc
ttctccggctccgggcttttgcccacggccaccgtccaggtgaagaccccggacggggag
aggctcgccacccacaccggggacggtcccgtagacgccgtgttcaaggccatccaggag
gccatcggcctgaggccggagcttgagctctaccgggtggaggccatcaccgggagcacc
gaggccttgggccaggtcacggtgcgcctccggctcggcgagctccaggccgtgggggtg
ggggtctccccggacatcattgaggcgagcgccttggcctttttggacgccgccgggaag
ctcgcctcgggccgggccacccggcacccgccctccattgaggaggttcaccgtggggtc
tag
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