Tupaia chinensis (Chinese tree shrew): 102494943
Entry
102494943 CDS
T02978
Gene name
DOT1L
Definition
(RefSeq) DOT1 like histone lysine methyltransferase
KO
K11427
histone-lysine N-methyltransferase, H3 lysine-79 specific [EC:
2.1.1.43
]
Organism
tup
Tupaia chinensis (Chinese tree shrew)
Pathway
tup00310
Lysine degradation
tup05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
tup00001
]
Metabolism
Amino acid metabolism
00310 Lysine degradation
102494943 (DOT1L)
Human Diseases
Cancers
05202 Transcriptional misregulation in cancers
102494943 (DOT1L)
Enzymes [BR:
tup01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.43 histone-lysine N-methyltransferase
102494943 (DOT1L)
Chromosome [BR:
tup03036
]
Eukaryotic Type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
102494943 (DOT1L)
SSDB
Motif
Pfam:
DOT1
Other DBs
NCBI-GeneID:
102494943
NCBI-ProteinID:
XP_014441023
LinkDB
Position
Un
AA seq
1526 aa
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHVLQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCR
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRESKSNATTPTKVP
ESRVAGPVDAPVDSGAEDDKAGATTVKKPSPSKARKKKLNKKGRKLAGRKRGRPKKLSTA
NPERKPKKSQAALELLHAQTVSQTAPSSPQDAYRSPHSPFYQLPPSAPRPCPTPLLAAPT
PPALQKLLESFKIQYLQFLAYTKTPQYRANLQQLLDQEKERNAQLLGAAQQLLSHCQAQK
EEIRGLFQQKLDELGVKALTYDDLIQAQKEISAHNQQLQEQSEQLEKDNCQLRSRSLQLL
KARCEELRLDWSTLSLESLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLR
SCVPPDDGLVPPPRGKGALGRELEAEAGRLHLELDCAKFSLPPFSVSPELSMNGHGAGYE
LGGPLSRPASKQSTPQYLASPPDQEVVPCTPSHGSRPRLEKLSSLALPDYTRLSPAKIVL
RRHLSQDPAGAGKTGTGELHSRAEHAKENGLTYQSPGVPSVKLSPQDPRPPSPGPTQAAG
EKGGEKPAKERGHGSSGEPITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAEKLRSTPS
PVPQPRDSSALEKPGGANAHGAGSKSLAAAPAGFYAGSVAISGALSGSPAPLAPGAELAA
FDESSSSGSLLGAVGSRSSTPQHPPPLAQPRPPGQASPVHRLAASPRLGGAAPGLLPEPG
KADLPSDAGFSDPEGEAKRRIVFTISAAAASARQSPSSKHSPLPSGARGDCGQGYGQDSR
KRGRRKRASAGTPSLSTGVSPKRRALPAVAGLFTQSSGSPLNLSSMVSTINQPLEITAIS
SPEDSRKSSPVPCQDHDQPPVLKKERPLSQANGAHYSPLTSDEEPGSEDEPSSARIERKI
ATISLESKSPPKTLETGGGMAGRRPTPASEPVVSSKWKSTFSPISDVGPAKPADGPLQAP
TLGQASLLAFRPTLDEPAAAEAKLVAHPRKSFPGALAGADGLSPGTNPXNGLAFGGGLAA
DLSLHSFNDGAPLPLRVPEASLSFPAPRGREGPSEANPFLNKRQLDGLCGLKAEAGKGRE
AAEDFRSGRNLFISAAAVPSGGLLGGPGLATAASSAGSTPPSAQTHRPFLGAFPPGPQFS
LGPVSLQANLSSVAGSSVLQSLFSTVPAAAGLAPATSATTRLTNSHAVGSFSGVTGGAVG
AGRKDAASTVNGGAPGGAGLAQLYCP
NT seq
4581 nt
+upstream
nt +downstream
nt
atgggcgagaagctggagctgaggctcaagtcgcccgtgggggccgagcccgccgtctac
ccgtggccgctgccggtctacgacaagcaccacgatgctgctcacgagatcatcgagacc
atccggtgggtctgcgaggagatcccggatcttaaactcgccatggagaactacgtcctg
atcgactacgacaccaagagcttcgagagcatgcagcggctctgtgacaagtacaaccgg
gccatcgacagcatccaccagctgtggaagggcaccacgcagcccatgaagctgaacacg
aggccgtccaccgggctgctgcggcacgtcctgcagcaggtgtacaaccactcggtcacc
gaccccgagaaactcaacaactacgagcccttctcccccgaggtctatggcgagacctcc
ttcgacctggtggcccagatgatcgacgagatcaagatgaccgaggacgacctcttcgtg
gacctgggcagcggtgtgggccaggtcgtgctccaggttgctgccgccaccaactgcaga
caccactacggcgtcgagaaagccgacatcccagccaagtacgcggagaccatggaccgc
gaattcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaaaga
ggtgacttcctctccgaggagtggcgggagcggatcgccaacacaagtgttatctttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcgcttcgcaaacatg
aaggagggtggcagaatcgtgtcctcgaaaccctttgcacctctaaacttcaggataaac
agccggaacttgagtgacattggcaccatcatgcgtgtggtggagctgtcgcccctgaag
ggctccgtgtcgtggacggggaagccggtctcctactacctgcacaccatcgaccgcacc
atacttgaaaactatttttctagtctgaaaaacccaaaactcagggaggaacaagaggcg
gcccggcgccggcagcagcgggagagcaagagcaacgccaccactccgaccaaggtcccc
gagagccgggtggccggccccgtggacgcccccgtggattctggtgctgaggacgacaag
gcgggagcgaccaccgtcaagaagccgtctccctccaaagctcgcaagaagaagctgaac
aagaaggggaggaagctggctggccggaagcgcgggcgcccgaagaagctgagcaccgcg
aaccccgagcgcaagcccaagaagagccaagctgcactggagctgctgcacgcacagacg
gtgtcccagacggccccctcctcgccccaggacgcctacaggtccccgcacagcccgttc
taccagctacctccgagcgcaccacggccgtgccccaccccactgctggcggcgcccacc
ccacctgcactgcagaagctgctagagtcctttaagatccagtacctgcagttcctggcc
tacaccaagaccccccagtacagagccaacctgcagcagctgctggaccaggagaaggag
aggaacgcccagctgctgggtgccgcgcagcagctcctcagccactgccaggcccagaag
gaggagatccgggggctgttccagcagaaactggacgagctgggcgtgaaggccttgacc
tacgatgacctgatccaagcgcagaaggagatctctgcgcacaaccagcagctgcaggag
cagtcggagcagctggagaaggacaactgtcagctccgcagccgcagcctgcagctgctc
aaggctcggtgcgaggagctgaggctggactggtccacgctgtccctggagagcctgctg
aaggagaagcaggccctgaagagccagatctccgagaagcagcgtcactgcctggagctg
cagatcagcatcgtggagctcgagaagagccagcggcagcaggagctgctgcagctcagg
tcctgcgtgccgcccgacgatgggctggtgccgcccccgcgcgggaagggtgccttgggc
cgcgagctggaggccgaggcgggccggctgcacctggagctggactgcgccaagttctcc
ctgccacccttcagcgtgagccccgagctgtccatgaacggccacggggcgggctacgag
ctgggcggcccgctgagccggccggcgtccaagcagagcaccccgcagtacctggcctcc
ccgcccgaccaggaggtggtgccctgcacgcccagccacggcagccggccccggctggag
aagctgtccagcctggccctgcctgactacaccaggctctcgccggccaagatcgtgctg
cggcggcacctgagccaggaccctgcgggtgctggcaagacgggaaccggcgagctccac
tctcgagctgagcacgccaaggagaacggcctcacctaccagagccccggcgtgccgagt
gtgaagctgagccctcaggacccgcggcccccgtccccagggcccacgcaggctgcaggg
gagaagggcggtgagaagcctgcgaaggagcgcggccacggcagcagcggcgagcccatc
accagcttgcccatcagcatcccgctcagcaccgtgcagcccaacaagctcccggtcagc
attcccctggctagcgtggttctgcccagccgcgccgagaagctgaggagcacgcccagc
cccgtgccgcagccccgagactcatctgcgctcgagaaaccgggcggcgctaatgcccat
ggggccgggagcaagagcttggccgcggcccccgcaggcttctacgccggctccgtggcc
atcagtggggccctgtccggcagcccggcacccctggcccccggagccgagctggccgcc
ttcgacgagtcctccagttcagggagcctcctcggtgccgtggggtcccggagctcgacg
ccgcagcacccgcccccgctggcgcagccccgcccccctggccaggcctcgcccgtgcac
cggctggccgccagtccccggctgggtggggccgccccgggcctcctccccgaacccggc
aaggccgacctgccctctgatgccggcttctcggacccggagggcgaagccaagcggagg
atcgtcttcaccatctcagccgcggctgccagcgccaggcagtcaccctccagcaagcac
agccctctgccctcgggagcccgaggggactgtggtcagggctacgggcaggacagccgc
aagcggggccgcaggaagagggcgtcggccgggacaccgagcctgagcacaggcgtgtct
cccaagcgccgtgccctgccagctgtcgccgggctcttcacgcagtcctcggggtcgccc
ctcaacctctcctccatggtcagcaccatcaaccagcccctggagatcacggcgatctcc
tcccccgaggactcacggaagagctcccctgtgccctgccaggaccacgaccagccgcct
gtgctcaagaaggagcggcccctgagccaggccaacggggcgcactactccccgctgacc
tccgacgaggagccgggctccgaggacgagcccagcagtgcccgaattgaaaggaaaatc
gcgacgatttccttggagagcaagtctcccccgaagaccttggagactgggggtggcatg
gcgggccggaggccgacacccgccagcgagcctgtcgtcagcagcaagtggaagtccacc
ttctcgcccatctccgacgtcggcccggccaagcccgcggacggccctctgcaggccccc
accctgggccaggcctccctgctcgccttccggcccaccctggacgagccggcggccgcg
gaggccaagctcgtcgcgcaccccaggaagagctttcccggcgccttggcgggggccgac
gggctcagccccggcaccaaccccngcaacggcttggccttcggcggcggtctggccgcg
gacctcagtttacacagcttcaacgatggtgctcccctccccctccgggtccccgaggcc
tcgctcagcttccccgccccgcggggcagggagggcccctcggaagccaacccctttctg
aacaagcggcagctggacggcctgtgcggcctgaaggccgaggcgggcaagggcagggag
gcggccgaggacttcaggagcggccgcaacctcttcatctccgccgccgccgtgccctcc
gggggcctcctgggcggccctggcctggccacagcggcgtcgtccgcgggcagcacgccg
ccctccgcacagacgcaccggcctttcctgggtgcctttccgcctggaccgcagttctcc
ctggggcccgtgtccctgcaggccaacctcagctctgtggccggctcgtcggtgctgcag
tccctgttcagcaccgtgccggccgccgcgggcctggcgcccgccacctctgccacgacc
agactgaccaactcccacgccgtgggcagcttctccggggtgacgggcggagcagtcgga
gcaggacggaaggacgcggcctctactgtgaacggcggcgctcccggaggcgccgggctg
gcccagctgtactgtccatag
DBGET
integrated database retrieval system
