Ursus maritimus (polar bear): 103657827
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Entry
103657827 CDS
T03271
Symbol
MAPK3
Name
(RefSeq) mitogen-activated protein kinase 3 isoform X1
KO
K04371
mitogen-activated protein kinase 1/3 [EC:
2.7.11.24
]
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr01521
EGFR tyrosine kinase inhibitor resistance
umr01522
Endocrine resistance
umr01524
Platinum drug resistance
umr04010
MAPK signaling pathway
umr04012
ErbB signaling pathway
umr04014
Ras signaling pathway
umr04015
Rap1 signaling pathway
umr04022
cGMP-PKG signaling pathway
umr04024
cAMP signaling pathway
umr04062
Chemokine signaling pathway
umr04066
HIF-1 signaling pathway
umr04068
FoxO signaling pathway
umr04071
Sphingolipid signaling pathway
umr04072
Phospholipase D signaling pathway
umr04114
Oocyte meiosis
umr04140
Autophagy - animal
umr04148
Efferocytosis
umr04150
mTOR signaling pathway
umr04151
PI3K-Akt signaling pathway
umr04210
Apoptosis
umr04218
Cellular senescence
umr04261
Adrenergic signaling in cardiomyocytes
umr04270
Vascular smooth muscle contraction
umr04350
TGF-beta signaling pathway
umr04360
Axon guidance
umr04370
VEGF signaling pathway
umr04371
Apelin signaling pathway
umr04380
Osteoclast differentiation
umr04510
Focal adhesion
umr04520
Adherens junction
umr04540
Gap junction
umr04550
Signaling pathways regulating pluripotency of stem cells
umr04611
Platelet activation
umr04613
Neutrophil extracellular trap formation
umr04620
Toll-like receptor signaling pathway
umr04621
NOD-like receptor signaling pathway
umr04625
C-type lectin receptor signaling pathway
umr04650
Natural killer cell mediated cytotoxicity
umr04657
IL-17 signaling pathway
umr04658
Th1 and Th2 cell differentiation
umr04659
Th17 cell differentiation
umr04660
T cell receptor signaling pathway
umr04662
B cell receptor signaling pathway
umr04664
Fc epsilon RI signaling pathway
umr04666
Fc gamma R-mediated phagocytosis
umr04668
TNF signaling pathway
umr04713
Circadian entrainment
umr04720
Long-term potentiation
umr04722
Neurotrophin signaling pathway
umr04723
Retrograde endocannabinoid signaling
umr04724
Glutamatergic synapse
umr04725
Cholinergic synapse
umr04726
Serotonergic synapse
umr04730
Long-term depression
umr04810
Regulation of actin cytoskeleton
umr04910
Insulin signaling pathway
umr04912
GnRH signaling pathway
umr04914
Progesterone-mediated oocyte maturation
umr04915
Estrogen signaling pathway
umr04916
Melanogenesis
umr04917
Prolactin signaling pathway
umr04919
Thyroid hormone signaling pathway
umr04921
Oxytocin signaling pathway
umr04926
Relaxin signaling pathway
umr04928
Parathyroid hormone synthesis, secretion and action
umr04929
GnRH secretion
umr04930
Type II diabetes mellitus
umr04933
AGE-RAGE signaling pathway in diabetic complications
umr04934
Cushing syndrome
umr04935
Growth hormone synthesis, secretion and action
umr04960
Aldosterone-regulated sodium reabsorption
umr05010
Alzheimer disease
umr05020
Prion disease
umr05022
Pathways of neurodegeneration - multiple diseases
umr05034
Alcoholism
umr05132
Salmonella infection
umr05133
Pertussis
umr05135
Yersinia infection
umr05140
Leishmaniasis
umr05142
Chagas disease
umr05145
Toxoplasmosis
umr05152
Tuberculosis
umr05160
Hepatitis C
umr05161
Hepatitis B
umr05163
Human cytomegalovirus infection
umr05164
Influenza A
umr05165
Human papillomavirus infection
umr05166
Human T-cell leukemia virus 1 infection
umr05167
Kaposi sarcoma-associated herpesvirus infection
umr05170
Human immunodeficiency virus 1 infection
umr05171
Coronavirus disease - COVID-19
umr05200
Pathways in cancer
umr05203
Viral carcinogenesis
umr05205
Proteoglycans in cancer
umr05206
MicroRNAs in cancer
umr05207
Chemical carcinogenesis - receptor activation
umr05208
Chemical carcinogenesis - reactive oxygen species
umr05210
Colorectal cancer
umr05211
Renal cell carcinoma
umr05212
Pancreatic cancer
umr05213
Endometrial cancer
umr05214
Glioma
umr05215
Prostate cancer
umr05216
Thyroid cancer
umr05218
Melanoma
umr05219
Bladder cancer
umr05220
Chronic myeloid leukemia
umr05221
Acute myeloid leukemia
umr05223
Non-small cell lung cancer
umr05224
Breast cancer
umr05225
Hepatocellular carcinoma
umr05226
Gastric cancer
umr05230
Central carbon metabolism in cancer
umr05231
Choline metabolism in cancer
umr05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
umr05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103657827 (MAPK3)
04012 ErbB signaling pathway
103657827 (MAPK3)
04014 Ras signaling pathway
103657827 (MAPK3)
04015 Rap1 signaling pathway
103657827 (MAPK3)
04350 TGF-beta signaling pathway
103657827 (MAPK3)
04370 VEGF signaling pathway
103657827 (MAPK3)
04371 Apelin signaling pathway
103657827 (MAPK3)
04668 TNF signaling pathway
103657827 (MAPK3)
04066 HIF-1 signaling pathway
103657827 (MAPK3)
04068 FoxO signaling pathway
103657827 (MAPK3)
04072 Phospholipase D signaling pathway
103657827 (MAPK3)
04071 Sphingolipid signaling pathway
103657827 (MAPK3)
04024 cAMP signaling pathway
103657827 (MAPK3)
04022 cGMP-PKG signaling pathway
103657827 (MAPK3)
04151 PI3K-Akt signaling pathway
103657827 (MAPK3)
04150 mTOR signaling pathway
103657827 (MAPK3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
103657827 (MAPK3)
04148 Efferocytosis
103657827 (MAPK3)
09143 Cell growth and death
04114 Oocyte meiosis
103657827 (MAPK3)
04210 Apoptosis
103657827 (MAPK3)
04218 Cellular senescence
103657827 (MAPK3)
09144 Cellular community - eukaryotes
04510 Focal adhesion
103657827 (MAPK3)
04520 Adherens junction
103657827 (MAPK3)
04540 Gap junction
103657827 (MAPK3)
04550 Signaling pathways regulating pluripotency of stem cells
103657827 (MAPK3)
09142 Cell motility
04810 Regulation of actin cytoskeleton
103657827 (MAPK3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
103657827 (MAPK3)
04613 Neutrophil extracellular trap formation
103657827 (MAPK3)
04620 Toll-like receptor signaling pathway
103657827 (MAPK3)
04621 NOD-like receptor signaling pathway
103657827 (MAPK3)
04625 C-type lectin receptor signaling pathway
103657827 (MAPK3)
04650 Natural killer cell mediated cytotoxicity
103657827 (MAPK3)
04660 T cell receptor signaling pathway
103657827 (MAPK3)
04658 Th1 and Th2 cell differentiation
103657827 (MAPK3)
04659 Th17 cell differentiation
103657827 (MAPK3)
04657 IL-17 signaling pathway
103657827 (MAPK3)
04662 B cell receptor signaling pathway
103657827 (MAPK3)
04664 Fc epsilon RI signaling pathway
103657827 (MAPK3)
04666 Fc gamma R-mediated phagocytosis
103657827 (MAPK3)
04062 Chemokine signaling pathway
103657827 (MAPK3)
09152 Endocrine system
04910 Insulin signaling pathway
103657827 (MAPK3)
04929 GnRH secretion
103657827 (MAPK3)
04912 GnRH signaling pathway
103657827 (MAPK3)
04915 Estrogen signaling pathway
103657827 (MAPK3)
04914 Progesterone-mediated oocyte maturation
103657827 (MAPK3)
04917 Prolactin signaling pathway
103657827 (MAPK3)
04921 Oxytocin signaling pathway
103657827 (MAPK3)
04926 Relaxin signaling pathway
103657827 (MAPK3)
04935 Growth hormone synthesis, secretion and action
103657827 (MAPK3)
04919 Thyroid hormone signaling pathway
103657827 (MAPK3)
04928 Parathyroid hormone synthesis, secretion and action
103657827 (MAPK3)
04916 Melanogenesis
103657827 (MAPK3)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
103657827 (MAPK3)
04270 Vascular smooth muscle contraction
103657827 (MAPK3)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
103657827 (MAPK3)
09156 Nervous system
04724 Glutamatergic synapse
103657827 (MAPK3)
04725 Cholinergic synapse
103657827 (MAPK3)
04726 Serotonergic synapse
103657827 (MAPK3)
04720 Long-term potentiation
103657827 (MAPK3)
04730 Long-term depression
103657827 (MAPK3)
04723 Retrograde endocannabinoid signaling
103657827 (MAPK3)
04722 Neurotrophin signaling pathway
103657827 (MAPK3)
09158 Development and regeneration
04360 Axon guidance
103657827 (MAPK3)
04380 Osteoclast differentiation
103657827 (MAPK3)
09159 Environmental adaptation
04713 Circadian entrainment
103657827 (MAPK3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103657827 (MAPK3)
05206 MicroRNAs in cancer
103657827 (MAPK3)
05205 Proteoglycans in cancer
103657827 (MAPK3)
05207 Chemical carcinogenesis - receptor activation
103657827 (MAPK3)
05208 Chemical carcinogenesis - reactive oxygen species
103657827 (MAPK3)
05203 Viral carcinogenesis
103657827 (MAPK3)
05230 Central carbon metabolism in cancer
103657827 (MAPK3)
05231 Choline metabolism in cancer
103657827 (MAPK3)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
103657827 (MAPK3)
09162 Cancer: specific types
05210 Colorectal cancer
103657827 (MAPK3)
05212 Pancreatic cancer
103657827 (MAPK3)
05225 Hepatocellular carcinoma
103657827 (MAPK3)
05226 Gastric cancer
103657827 (MAPK3)
05214 Glioma
103657827 (MAPK3)
05216 Thyroid cancer
103657827 (MAPK3)
05221 Acute myeloid leukemia
103657827 (MAPK3)
05220 Chronic myeloid leukemia
103657827 (MAPK3)
05218 Melanoma
103657827 (MAPK3)
05211 Renal cell carcinoma
103657827 (MAPK3)
05219 Bladder cancer
103657827 (MAPK3)
05215 Prostate cancer
103657827 (MAPK3)
05213 Endometrial cancer
103657827 (MAPK3)
05224 Breast cancer
103657827 (MAPK3)
05223 Non-small cell lung cancer
103657827 (MAPK3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
103657827 (MAPK3)
05170 Human immunodeficiency virus 1 infection
103657827 (MAPK3)
05161 Hepatitis B
103657827 (MAPK3)
05160 Hepatitis C
103657827 (MAPK3)
05171 Coronavirus disease - COVID-19
103657827 (MAPK3)
05164 Influenza A
103657827 (MAPK3)
05163 Human cytomegalovirus infection
103657827 (MAPK3)
05167 Kaposi sarcoma-associated herpesvirus infection
103657827 (MAPK3)
05165 Human papillomavirus infection
103657827 (MAPK3)
09171 Infectious disease: bacterial
05132 Salmonella infection
103657827 (MAPK3)
05135 Yersinia infection
103657827 (MAPK3)
05133 Pertussis
103657827 (MAPK3)
05152 Tuberculosis
103657827 (MAPK3)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
103657827 (MAPK3)
05140 Leishmaniasis
103657827 (MAPK3)
05142 Chagas disease
103657827 (MAPK3)
09164 Neurodegenerative disease
05010 Alzheimer disease
103657827 (MAPK3)
05020 Prion disease
103657827 (MAPK3)
05022 Pathways of neurodegeneration - multiple diseases
103657827 (MAPK3)
09165 Substance dependence
05034 Alcoholism
103657827 (MAPK3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
103657827 (MAPK3)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
103657827 (MAPK3)
04933 AGE-RAGE signaling pathway in diabetic complications
103657827 (MAPK3)
04934 Cushing syndrome
103657827 (MAPK3)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103657827 (MAPK3)
01524 Platinum drug resistance
103657827 (MAPK3)
01522 Endocrine resistance
103657827 (MAPK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
umr01001
]
103657827 (MAPK3)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
umr03036
]
103657827 (MAPK3)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
umr04147
]
103657827 (MAPK3)
Enzymes [BR:
umr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
103657827 (MAPK3)
Protein kinases [BR:
umr01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
103657827 (MAPK3)
Chromosome and associated proteins [BR:
umr03036
]
Eukaryotic type
Centromeric chromatin formation proteins
SAC (spindle assembly checkpoint) factors
Protein kinases
103657827 (MAPK3)
Exosome [BR:
umr04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
103657827 (MAPK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
APH
Haspin_kinase
Choline_kinase
FTA2
Kdo
Motif
Other DBs
NCBI-GeneID:
103657827
NCBI-ProteinID:
XP_040491056
UniProt:
A0A8M1G600
LinkDB
All DBs
Position
Unknown
AA seq
379 aa
AA seq
DB search
MAAAAAQGGGGGEPRGADGVGPGVSGEVEVVKGQPFDVGPRYTELHYIGEGAYGMVSSAY
DHVRKIRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAPTLEAMRDVYI
VQDLMETDLYKLLKSQQLSNDHVCYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL
KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD
SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFDMELDDLPKERL
KELIFQETARFQPGALEAP
NT seq
1140 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggcggcggctcaggggggcgggggcggggagccccggggagctgatggggtc
ggcccgggggtctcgggggaggtggaggtagtgaaggggcagccgttcgacgtgggcccg
cgctacacggagctgcattacatcggcgagggcgcgtacggcatggtcagctcagcttac
gaccacgtgcgcaagattcgcgtggccatcaagaaaatcagccccttcgagcatcagacc
tactgccagcgcacactgcgggagatccagatcttgctgcgcttccgccacgagaacgtc
attggcattcgggacattctgcgggcgcccaccctggaagccatgagagatgtctacatt
gtgcaggacctgatggagacagacctgtacaagttgctcaaaagccagcagctgagcaac
gaccatgtttgctacttcctctaccagatcctgcggggcctcaagtacatccactcagcc
aacgtgctccaccgggatctaaagccctctaacctgctcatcaacaccacctgcgacctt
aagatctgcgattttggcctggcccggattgcggaccctgagcatgaccacactggcttc
ctgacagaatatgtggccacacgctggtaccgggctccagaaatcatgcttaactctaag
ggctacaccaagtccatcgacatctggtctgtgggctgcattctggctgagatgctctcc
aaccggcccatcttccctggcaagcactacctggaccagctcaaccacattctgggtatc
ctgggctccccatcccaggaggacttgaattgtatcatcaatatgaaggcccgaaactac
ctgcagtctctgccctccaagaccaaggtggcctgggccaagctttttcccaagtcggac
tccaaagcccttgacctgctagaccggatgttgacctttaaccccaacaaacggatcaca
gtggaagaagcgctggctcacccctacttggagcagtactacgacccaacagatgagccg
gtggccgaggagcctttcacctttgacatggagctggatgatctacccaaggagcggctg
aaggagctcatcttccaggagacagcccgcttccagcctggggcgctggaggccccctaa
DBGET
integrated database retrieval system