Ursus maritimus (polar bear): 103671891
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Entry
103671891 CDS
T03271
Symbol
SOS1
Name
(RefSeq) son of sevenless homolog 1 isoform X1
KO
K03099
son of sevenless
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr01521
EGFR tyrosine kinase inhibitor resistance
umr01522
Endocrine resistance
umr04010
MAPK signaling pathway
umr04012
ErbB signaling pathway
umr04014
Ras signaling pathway
umr04062
Chemokine signaling pathway
umr04068
FoxO signaling pathway
umr04072
Phospholipase D signaling pathway
umr04150
mTOR signaling pathway
umr04151
PI3K-Akt signaling pathway
umr04510
Focal adhesion
umr04540
Gap junction
umr04630
JAK-STAT signaling pathway
umr04650
Natural killer cell mediated cytotoxicity
umr04660
T cell receptor signaling pathway
umr04662
B cell receptor signaling pathway
umr04664
Fc epsilon RI signaling pathway
umr04714
Thermogenesis
umr04722
Neurotrophin signaling pathway
umr04810
Regulation of actin cytoskeleton
umr04910
Insulin signaling pathway
umr04912
GnRH signaling pathway
umr04915
Estrogen signaling pathway
umr04917
Prolactin signaling pathway
umr04926
Relaxin signaling pathway
umr04935
Growth hormone synthesis, secretion and action
umr05034
Alcoholism
umr05160
Hepatitis C
umr05161
Hepatitis B
umr05163
Human cytomegalovirus infection
umr05165
Human papillomavirus infection
umr05200
Pathways in cancer
umr05205
Proteoglycans in cancer
umr05206
MicroRNAs in cancer
umr05207
Chemical carcinogenesis - receptor activation
umr05208
Chemical carcinogenesis - reactive oxygen species
umr05210
Colorectal cancer
umr05211
Renal cell carcinoma
umr05213
Endometrial cancer
umr05214
Glioma
umr05215
Prostate cancer
umr05220
Chronic myeloid leukemia
umr05221
Acute myeloid leukemia
umr05223
Non-small cell lung cancer
umr05224
Breast cancer
umr05225
Hepatocellular carcinoma
umr05226
Gastric cancer
umr05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103671891 (SOS1)
04012 ErbB signaling pathway
103671891 (SOS1)
04014 Ras signaling pathway
103671891 (SOS1)
04630 JAK-STAT signaling pathway
103671891 (SOS1)
04068 FoxO signaling pathway
103671891 (SOS1)
04072 Phospholipase D signaling pathway
103671891 (SOS1)
04151 PI3K-Akt signaling pathway
103671891 (SOS1)
04150 mTOR signaling pathway
103671891 (SOS1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
103671891 (SOS1)
04540 Gap junction
103671891 (SOS1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
103671891 (SOS1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
103671891 (SOS1)
04660 T cell receptor signaling pathway
103671891 (SOS1)
04662 B cell receptor signaling pathway
103671891 (SOS1)
04664 Fc epsilon RI signaling pathway
103671891 (SOS1)
04062 Chemokine signaling pathway
103671891 (SOS1)
09152 Endocrine system
04910 Insulin signaling pathway
103671891 (SOS1)
04912 GnRH signaling pathway
103671891 (SOS1)
04915 Estrogen signaling pathway
103671891 (SOS1)
04917 Prolactin signaling pathway
103671891 (SOS1)
04926 Relaxin signaling pathway
103671891 (SOS1)
04935 Growth hormone synthesis, secretion and action
103671891 (SOS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
103671891 (SOS1)
09159 Environmental adaptation
04714 Thermogenesis
103671891 (SOS1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103671891 (SOS1)
05206 MicroRNAs in cancer
103671891 (SOS1)
05205 Proteoglycans in cancer
103671891 (SOS1)
05207 Chemical carcinogenesis - receptor activation
103671891 (SOS1)
05208 Chemical carcinogenesis - reactive oxygen species
103671891 (SOS1)
05231 Choline metabolism in cancer
103671891 (SOS1)
09162 Cancer: specific types
05210 Colorectal cancer
103671891 (SOS1)
05225 Hepatocellular carcinoma
103671891 (SOS1)
05226 Gastric cancer
103671891 (SOS1)
05214 Glioma
103671891 (SOS1)
05221 Acute myeloid leukemia
103671891 (SOS1)
05220 Chronic myeloid leukemia
103671891 (SOS1)
05211 Renal cell carcinoma
103671891 (SOS1)
05215 Prostate cancer
103671891 (SOS1)
05213 Endometrial cancer
103671891 (SOS1)
05224 Breast cancer
103671891 (SOS1)
05223 Non-small cell lung cancer
103671891 (SOS1)
09172 Infectious disease: viral
05161 Hepatitis B
103671891 (SOS1)
05160 Hepatitis C
103671891 (SOS1)
05163 Human cytomegalovirus infection
103671891 (SOS1)
05165 Human papillomavirus infection
103671891 (SOS1)
09165 Substance dependence
05034 Alcoholism
103671891 (SOS1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103671891 (SOS1)
01522 Endocrine resistance
103671891 (SOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
PH
PH_19
PH_10
IQ_SEC7_PH
Takusan
Motif
Other DBs
NCBI-GeneID:
103671891
NCBI-ProteinID:
XP_040479067
UniProt:
A0A8M1FB16
LinkDB
All DBs
Position
Unknown
AA seq
1333 aa
AA seq
DB search
MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESSDDALQYVEELILQLLNMLC
QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASNAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI
IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGT
VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSSDTVFIQVSLPHGPRSASVSSISL
TKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISD
RTSLSDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPP
PQTPSPHGTRRHLPSPPLTQEVDLPSVTGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
RDGPPLLENAHSS
NT seq
4002 nt
NT seq
+upstream
nt +downstream
nt
atgcaggcgcagcagctgccgtacgagtttttcagcgaggagaacgcacccaagtggcgg
gggctgctggtgccggcgctgaaaaaggtccaggggcaagttcatccgactcttgagtct
agtgatgatgctcttcagtatgttgaggaattaattttgcagttattaaatatgctatgc
caagctcagccccgaagcgcttcagatgtagaggaacgtgttcaaaaaagtttccctcat
ccaattgataagtgggcaatagctgatgcccaatcggctattgaaaagaggaagcgaaga
aaccctttatctctcccagtagaaaaaattcatcctttactaaaggaggtcctaggttat
aaaattgaccaccaggtttctgtttacatagtagcagtattagaatacatttctgcagac
atcttaaagctggtggggaattatgtacgaaatatacggcattatgaaattacaaaacaa
gatattaaagtggcaatgtgtgctgataaggtattaatggacatgtttcatcaagatgta
gaagatataaatatattatctttaactgatgaagagccttccacctcaggagagcaaact
tattatgatttggtaaaagcatttatggcagaaattcgacagtacataagggaactaaat
ttaattataaaagtttttagagagccctttgtctccaattcaaaattgttttcagctaat
gatgtagaaaatatatttagccgtatagtagatatacacgaacttagtgtaaagttactg
ggccatatagaagatactgtggaaatgactgatgaaggtagcccccatcccttagtagga
agctgctttgaagacttagcagaggaactggcatttgatccatatgaatcatatgctcga
gatattttacggcctggttttcatgatcgtttccttagtcagttatcaaagcctggagcg
gcactctatttacagtcaataggcgaaggtttcaaagaagctgttcagtatgttttaccc
aggctacttctagcccctgtttaccactgtctacattactttgaacttttgaagcagtta
gaagaaaagagtgaagatcaagaagacaaggaatgtttgaaacaagcaataacagctttg
cttaatgttcagagtggtatggaaaaaatatgttctaaaagtcttgcaaaacgaagactg
agtgaatctgcatgtcggttttatagtcagcaaatgaaggggaaacaactagcaatcaag
aaaatgaacgagattcaaaagaatattgatggttgggagggaaaagacattggacagtgt
tgcaatgaatttataatggaaggaactcttacacgtgtaggagccaaacatgaaagacac
atatttctctttgatggcttaatgatttgctgtaaatcaaaccatgggcagccaagactc
cctggtgctagcaacgcagagtatcgtcttaaagaaaagtttttcatgagaaaggtacaa
attaatgacaaagatgacaccagtgagtacaagcatgcttttgaaataattttaaaagat
gaaaatagtgttatattttctgccaagtcagctgaagagaaaaacaattggatggcagca
ctgatatctttacagtaccggagtacgctggagaggatgctcgatgtgacgatgctgcag
gaagagaaggaggagcagatgaggctccctagtgccgatgtttatagatttgcagagcct
gactctgaagagaatataatatttgaagaaaacatgcagcccaaggctggaatcccaatt
atcaaagcgggaactgttattaaacttatagagaggctcacataccatatgtatgcagat
cccaattttgttcggacatttcttacaacatacagatccttttgtaaacctcaagaacta
ctgagtcttataatagaaaggtttgaaattccagagcctgagccaacagaagctgatcgc
atagccatagagaatggagatcagcccttgagtgcagaactaaaaaggtttagaaaagaa
tacatacagcctgtacagctgcgagtattaaatgtatgtcggcattgggtagagcaccac
ttctatgattttgaaagggatgcagatcttttgcagcgaatggaagaatttattggaaca
gtgagaggtaaagcaatgaaaaaatgggttgaatccatcactaaaataatccaaaggaaa
aaaattgcaagagacaatggaccaggtcataatattacatttcagagttcacctcccaca
gttgagtggcatataagcaggcctgggcacatagagacttttgacctgctcaccttacac
ccaatagaaattgctcgacaactcactttacttgaatcagatctatatcgagctgtacag
ccatcagaattagttggaagtgtgtggacaaaagaagacaaagaaattaattctcctaat
cttctaaaaatgatccggcataccactaacctcactctgtggtttgagaaatgtattgta
gaaactgaaaacttagaagaaagagtagctgtggtgagtcgaataattgagattctacaa
gtctttcaagagctgaacaacttcaacggtgtccttgaggttgtcagtgctatgaactcc
tcacctgtttacagactagaccacacatttgagcaaataccaagtcgccaaaagaaaatt
ttagaagaagctcatgaattaagtgaagatcactataagaaatatttggcaaaactcagg
tctattaatccaccgtgcgtgcctttctttggaatttatctaactaatatcttgaaaaca
gaagaaggcaaccctgaggtcctaaaaaggcatggaaaagagcttataaactttagcaaa
aggaggaaagtagcagaaataacaggagagatccagcaataccaaaatcagccttattgt
ttacgagtagaatcagatatcaaaaggttctttgaaaatttgaatccaatgggaaatagc
atggaaaaagaatttacagattatcttttcaacaaatccctagaaatagaaccacgaaac
cctaagcctctcccaagatttccaaaaaaatatagctatcccctaaaatctcctggtgtt
cgtccatcaaacccaagaccaggtaccatgagacatcccacacctctgcagcaggagccc
aggaaaatcagttacagtaggatccccgaaagtgaaacagaaagtacagcgtctgcaccg
aattctccaagaacaccgttaacacctccgcctgcttccggcgcttctagtaccacggat
gtttgcagcgtttttgattccgatcattcgagcccttttcactcaagcagcgataccgtc
tttatccaagtttcactgccccatggcccaagatctgcttcagtatcatctataagtcta
accaagggcactgatgaagtgcctgtcccccctcctgtccctccacgaagacggccagaa
tccgcccccgccgagtcttcgccgtctaagattatgtctaagcatttggacagcccccca
gcaattcctcctaggcagcccacatcaaaagcctattcaccacgatattcaatatcagac
cggacctcgctatcagaccctcctgagagccctcccttattaccaccacgagaacctgtg
aggacacctgatgttttctccagctcaccactacatctgcagcctccccctttgggcaaa
aaaagtgatcatggcaatgccttcttcccgaacagcccttccccttttacaccgcctcct
cctcaaacaccctctcctcatggcacgagaaggcatctgccatcgccaccactgacacaa
gaagtggaccttccttccgtcactgggccgcctgttcctccacgacaaagcacttctcaa
catatccctaaactccctccaaaaacttacaaaagggagcacacacacccatccatgcac
agggatggcccaccgctgctggagaacgcccattcgtcctga
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integrated database retrieval system
