KEGG   ENZYME: 1.1.1.388Help
Entry
EC 1.1.1.388                Enzyme                                 

Name
glucose-6-phosphate dehydrogenase (NAD+);
Glc6PDH;
azf (gene name);
archaeal zwischenferment
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
D-glucose-6-phosphate:NAD+ 1-oxidoreductase
Reaction(IUBMB)
D-glucose 6-phosphate + NAD+ = 6-phospho-D-glucono-1,5-lactone + NADH + H+ [RN:R10520]
Reaction(KEGG)
Substrate
D-glucose 6-phosphate [CPD:C00092];
NAD+ [CPD:C00003]
Product
6-phospho-D-glucono-1,5-lactone [CPD:C01236];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme catalyses a step of the pentose phosphate pathway. The enzyme from the archaeon Haloferax volcanii is specific for NAD+. cf. EC 1.1.1.363, glucose-6-phosphate dehydrogenase [NAD(P)+] and EC 1.1.1.49, glucose-6-phosphate dehydrogenase (NADP+).
History
EC 1.1.1.388 created 2015
Pathway
Pentose phosphate pathway
Orthology
K19243  
NAD+ dependent glucose-6-phosphate dehydrogenase
Genes
PBA: 
BAE: 
BATR: 
BRX: 
HAL: 
HSL: 
HDL: 
HHB: 
HJE: 
HALH: 
HHSR: 
HMA: 
HHI: 
HHN: 
HAB: 
NPH: 
NMO: 
HMU: 
HALI: 
HSU: 
HSF: 
HWA: 
HWC: 
HVO: 
HME: 
HGI: 
HBO: 
HLA: 
HTU: 
HDA: 
NMG: 
HXA: 
NAT: 
NPE: 
NGE: 
HRU: 
NOU: 
SALI: 
HLR: 
HLC: 
HAH: 
 » show all
Taxonomy
Reference
1  [PMID:25836736]
  Authors
Pickl A, Schonheit P
  Title
The oxidative pentose phosphate pathway in the haloarchaeon Haloferax volcanii involves a novel type of glucose-6-phosphate dehydrogenase--The archaeal Zwischenferment.
  Journal
FEBS. Lett. 589 (2015) 1105-11.
  Sequence
[hvo:HVO_0511]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
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