KEGG   COMPOUND: C00334Help
Entry
C00334                      Compound                               

Name
4-Aminobutanoate;
4-Aminobutanoic acid;
4-Aminobutyrate;
4-Aminobutyric acid;
gamma-Aminobutyric acid;
GABA
Formula
C4H9NO2
Exact mass
103.0633
Mol weight
103.1198
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
Same as: D00058
Reaction
Pathway
map00250  Alanine, aspartate and glutamate metabolism
map00330  Arginine and proline metabolism
map00410  beta-Alanine metabolism
map00650  Butanoate metabolism
map00760  Nicotinate and nicotinamide metabolism
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map02024  Quorum sensing
map04024  cAMP signaling pathway
map04080  Neuroactive ligand-receptor interaction
map04721  Synaptic vesicle cycle
map04723  Retrograde endocannabinoid signaling
map04727  GABAergic synapse
map04742  Taste transduction
map04915  Estrogen signaling pathway
map05032  Morphine addiction
map05033  Nicotine addiction
Module
M00027  GABA (gamma-Aminobutyrate) shunt
M00135  GABA biosynthesis, eukaryotes, putrescine => GABA
M00136  GABA biosynthesis, prokaryotes, putrescine => GABA
Enzyme
1.2.1.3         1.2.1.19        1.2.1.-         1.5.3.19        
2.1.4.1         2.6.1.19        2.6.1.96        3.4.13.18       
3.4.13.20       3.5.1.63        3.5.1.94        3.5.3.7         
4.1.1.15        6.3.2.11
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Other amino acids
    C00334  gamma-Aminobutyric acid
  Amines
   Biogenic amines
    C00334  gamma-Aminobutyric acid (GABA)
 Hormones and transmitters
  Neurotransmitters
   Amino acids
    C00334  GABA
Lipids [BR:br08002]
 FA  Fatty acyls
  FA01 Fatty Acids and Conjugates
   FA0110 Amino fatty acids
    C00334  4-Aminobutanoic acid
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N03 ANTIEPILEPTICS
   N03A ANTIEPILEPTICS
    N03AG Fatty acid derivatives
     N03AG03 Aminobutyric acid
      D00058  gamma-Aminobutyric acid (JAN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   219  Miscellaneous
    2190  Miscellaneous
     D00058  gamma-Aminobutyric acid (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Metabotropic glutamate receptor family
   GABA
    GABAB-receptor
     Aminobutyric acid
      D00058  gamma-Aminobutyric acid (JAN)
 Ion channels
  Cys-loop superfamily
   GABA-A
    GABAA-receptor (benzodiazepine binding site)
     Aminobutyric acid
      D00058  gamma-Aminobutyric acid (JAN)
Drug classes of therapeutic agents [br08360.html]
 Neurological agents
  D00058
BRITE hierarchy
Other DBs
CAS: 56-12-2
PubChem: 3628
ChEBI: 16865 30566
ChEMBL: CHEMBL96
LIPIDMAPS: LMFA01100039
KNApSAcK: C00001337
PDB-CCD: ABU[PDBj]
3DMET: B00090
NIKKAJI: J1.375G
LinkDB All DBs
KCF data Show

ATOM        7
            1   C1b C    21.8376  -18.3787
            2   C6a C    23.0478  -17.6770
            3   C1b C    20.6274  -17.6770
            4   O6a O    24.2580  -18.3850
            5   O6a O    23.0478  -16.2803
            6   C1b C    19.4108  -18.3787
            7   N1a N    18.2006  -17.6770
BOND        6
            1     1   2 1
            2     1   3 1
            3     2   4 1
            4     2   5 2
            5     3   6 1
            6     6   7 1

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