KEGG   DRUG: ZalcitabineHelp
Entry
D00412                      Drug                                   

Name
Zalcitabine (JAN/USP/INN);
Hivid (TN)
Formula
C9H13N3O3
Exact mass
211.0957
Mol weight
211.2178
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Antiviral
 DG01440  Arabinofuranosyl type antiviral
 DG01890  Nucleoside reverse transcriptase inhibitor
 DG01656  HIV reverse transcriptase inhibitor
Remark
Same as: 
ATC code: 
Efficacy
Antiviral, Reverse transcriptase inhibitor
Comment
Nucleoside reverse transcriptase inhibitor (NRTI)
Target
RNA-directed DNA polymerase
Metabolism
Transporter: SLC22A6 [HSA:9356]
Interaction
Drug interaction
Structure map
Antiviral agents
Anti-HIV agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AF Nucleoside and nucleotide reverse transcriptase inhibitors
     J05AF03 Zalcitabine
      D00412  Zalcitabine (JAN/USP/INN)
Antiinfectives [BR:br08307]
 Antivirals
  Anti-HIV agents
   Reverse transcriptase inhibitor (RTI)
    Nucleoside and nucleotide reverse transcriptase inhibitor (NRTIs)
     Zalcitabine
      D00412  Zalcitabine (JAN/USP/INN)
Cytochrome P450 interactions [BR:br08309]
 Transporter substrates
  OAT1
   Zalcitabine
    D00412  Zalcitabine (JAN/USP/INN)
  OAT3
   Zalcitabine
    D00412  Zalcitabine (JAN/USP/INN)
Orphan drugs in the USA [br08355.html]
 Orphan drugs in the USA
  D00412
BRITE hierarchy
Other DBs
CAS: 
7481-89-2
PubChem: 
ChEBI: 
ChEMBL: 
DrugBank: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        15
            1   C1x C    18.1827  -18.2480
            2   C1y C    18.5900  -16.9111
            3   O2x O    17.4593  -16.0809
            4   C1y C    16.3457  -16.9339
            5   C1x C    16.7800  -18.2622
            6   N4y N    19.7751  -16.1976
            7   C8y C    20.9746  -16.8869
            8   N5x N    22.2298  -16.1727
            9   C8y C    22.2156  -14.7700
            10  C8x C    21.0162  -14.0808
            11  C8x C    19.7609  -14.7950
            12  O5x O    20.9888  -18.2895
            13  N1a N    23.4007  -14.0565
            14  C1b C    15.1463  -16.2446
            15  O1a O    13.9611  -16.9581
BOND        16
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     1   5 1
            6     2   6 1 #Up
            7     6   7 1
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11   10  11 2
            12    6  11 1
            13    7  12 2
            14    9  13 1
            15    4  14 1 #Up
            16   14  15 1

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