KEGG   DRUG: NitrofurantoinHelp
Entry
D00439                      Drug                                   

Name
Nitrofurantoin (JAN/USP/INN);
Furadantin (TN)
Product
NITROFURANTION MACROCRYSTALS (A-S Medication Solutions), NITROFURANTION MACROCRYSTALS (A-S Medication Solutions), NITROFURANTION MACROCRYSTALS (Aidarex Pharmaceuticals LLC), NITROFURANTION MACROCRYSTALS (Alvogen), NITROFURANTION MACROCRYSTALS (Apotheca), NITROFURANTION MACROCRYSTALS (Lake Erie Medical DBA Quality Care Products LLC), NITROFURANTION MACROCRYSTALS (Lake Erie Medical DBA Quality Care Products LLC), NITROFURANTION MACROCRYSTALS (NuCare Pharmaceuticals), NITROFURANTION MACROCRYSTALS (PD-Rx Pharmaceuticals), NITROFURANTION MACROCRYSTALS (PD-Rx Pharmaceuticals), NITROFURANTION MACROCRYSTALS (Proficient Rx LP), NITROFURANTION MACROCRYSTALS (REMEDYREPACK), NITROFURANTION MACROCRYSTALS (REMEDYREPACK), NITROFURANTION MACROCRYSTALS (REMEDYREPACK), NITROFURANTION MACROCRYSTALS (REMEDYREPACK), NITROFURANTION MACROCRYSTALS (REMEDYREPACK), NITROFURANTION MACROCRYSTALS (REMEDYREPACK), NITROFURANTOIN (Northwind Pharmaceuticals), FURADANTIN (Shionogi), MACRODANTIN (Almatica Pharma), NITROFURANTOIN MACROCRYSTALS (American Health Packaging), NITROFURANTOIN MACROCRYSTALS (BluePoint Laboratories)
  Generic
NITROFURANTION (Sun Pharmaceutical Industries), NITROFURANTOIN (Actavis Pharma), NITROFURANTOIN (Actavis Pharma), NITROFURANTOIN (Amneal Pharmaceuticals of New York), NITROFURANTOIN (Caraco Pharmaceutical Laboratories), NITROFURANTOIN (GAVIS Pharmaceuticals), NITROFURANTOIN (NCS HealthCare of KY), NITROFURANTOIN (Nostrum Laboratories), NITROFURANTOIN (Novel Laboratories), NITROFURANTOIN (PD-Rx Pharmaceuticals), NITROFURANTOIN (Prasco Laboratories), NITROFURANTOIN (MACROCRYSTALS) (A-S Medication Solutions LLC), NITROFURANTOIN (MACROCRYSTALS) (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), NITROFURANTOIN (MACROCRYSTALS) (Mylan Institutional), NITROFURANTOIN (MACROCRYSTALS) (Mylan Pharmaceuticals), NITROFURANTOIN (MACROCRYSTALS) (PD-Rx Pharmaceuticals), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (American Health Packaging), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Northstar RxLLC), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (REMEDYREPACK), NITROFURANTOIN MACROCRYSTALS (A-S Medication Solutions LLC), NITROFURANTOIN MACROCRYSTALS (Blenheim Pharmacal), NITROFURANTOIN MACROCRYSTALS (Bryant Ranch Prepack), NITROFURANTOIN MACROCRYSTALS (Impax Generics), NITROFURANTOIN MACROCRYSTALS (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), NITROFURANTOIN MACROCRYSTALS (Liberty Pharmaceuticals), NITROFURANTOIN MACROCRYSTALS (Liberty Pharmaceuticals), NITROFURANTOIN MACROCRYSTALS (PD-Rx Pharmaceuticals), NITROFURANTOIN MACROCRYSTALS (Physicians Total Care), NITROFURANTOIN MACROCRYSTALS (Rebel Distributors Corp), NITROFURANTOIN MACROCRYSTALS (RedPharm Drug), NITROFURANTOIN MACROCRYSTALS (STAT RX USA LLC), NITROFURANTOIN MACROCRYSTALS (Teva Pharmaceuticals USA), NITROFURANTOIN MACROCRYSTALS (Unit Dose Services)
Formula
C8H6N4O5
Exact mass
238.0338
Mol weight
238.157
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Antibacterial
 DG01552  Hydantoin type nitrofuran
Remark
Same as: 
ATC code: 
Activity
Antibacterial
Comment
Nitrofuran derivative
Interaction
Genomic biomarker: G6PD [HSA:2539]
Drug interaction
Other map
Bile secretion
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01X OTHER ANTIBACTERIALS
    J01XE Nitrofuran derivatives
     J01XE01 Nitrofurantoin
      D00439  Nitrofurantoin (JAN/USP/INN)
USP drug classification [BR:br08302]
 Antibacterials
  Antibacterials, Other
   Nitrofurantoin
    D00439  Nitrofurantoin (JAN/USP/INN)
Antiinfectives [BR:br08307]
 Antibacterials
  Others
   Bactericidal action
    Hydantoin type nitrofurans
     Nitrofurantoin; Veterinary
      D00439  Nitrofurantoin (JAN/USP/INN)
Antibacterials [br08350.html]
 D00439
Pharmacogenomic biomarkers in FDA drug labels [br08341.html]
 Polymorphisms and germline mutations
  D00439
BRITE hierarchy
Other DBs
CAS: 
67-20-9
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        17
            1   N1x N    23.7300  -16.2400
            2   C5x C    23.3100  -14.9800
            3   C1x C    21.9800  -14.9800
            4   N1y N    21.5600  -16.2400
            5   C5x C    22.6100  -17.0800
            6   O5x O    22.6100  -18.4800
            7   O5x O    24.0800  -13.8600
            8   N2b N    20.3700  -16.9400
            9   C2b C    19.1800  -16.2400
            10  C8y C    17.9900  -16.9400
            11  O2x O    16.8700  -16.1000
            12  C8y C    15.7500  -16.9400
            13  C8x C    16.1700  -18.2700
            14  C8x C    17.5700  -18.2700
            15  N2b N    14.6300  -16.2400 #+
            16  O3a O    13.1600  -17.2200 #-
            17  O3a O    14.6300  -14.9100
BOND        18
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     1   5 1
            6     5   6 2
            7     2   7 2
            8     8   9 2
            9     8   4 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 2
            14   13  14 1
            15   10  14 2
            16   12  15 1
            17   15  16 1
            18   15  17 2

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