KEGG   DRUG: PrimidoneHelp
Entry
D00474                      Drug                                   

Name
Primidone (JP17/USP/INN);
Mysoline (TN)
Product
  Generic
Formula
C12H14N2O2
Exact mass
218.1055
Mol weight
218.2518
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01904  Barbiturate antiepileptics
Cyp substrate
 DG01639  CYP2C19 substrate
Remark
Same as: C07371
Therapeutic category: 1135
ATC code: N03AA03
Product: D00474<JP/US>
Efficacy
Antiepileptic
Comment
Barubiturate derivative
Active form of prodrug: Phenobarbital [DR:D00506], Phenylethylmalonamide [CPD:C07499]
Interaction
Drug interaction
Structure map
map07033  Anticonvulsants
map07230  GABA-A receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N03 ANTIEPILEPTICS
   N03A ANTIEPILEPTICS
    N03AA Barbiturates and derivatives
     N03AA03 Primidone
      D00474  Primidone (JP17/USP/INN)
USP drug classification [BR:br08302]
 Anticonvulsants
  Gamma-aminobutyric Acid (GABA) Augmenting Agents
   Primidone
    D00474  Primidone (JP17/USP/INN)
   Primidone
    D00474  Primidone (JP17/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   113  Antiepileptics
    1135  Primidones
     D00474  Primidone (JP17/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00474  Primidone
Drug classes of therapeutic agents [br08360.html]
 Neurological agents
  D00474
Prodrugs [br08324.html]
 D00474
BRITE hierarchy
Other DBs
CAS: 125-33-7
PubChem: 7847540
ChEBI: 8412
ChEMBL: CHEMBL856
DrugBank: DB00794
LigandBox: D00474
NIKKAJI: J3.260C
LinkDB All DBs
KCF data Show

ATOM        16
            1   C1z C    22.4914  -18.6613
            2   C8y C    23.6964  -17.9536
            3   C5x C    21.2571  -17.9768
            4   C5x C    22.4914  -20.0653
            5   C1b C    23.6964  -19.3574
            6   C8x C    24.9073  -18.6379
            7   C8x C    23.7489  -16.5496
            8   N1x N    20.0522  -18.6613
            9   O5x O    21.2571  -16.5554
            10  N1x N    21.2571  -20.7673
            11  O5x O    23.6847  -20.7673
            12  C1a C    25.0946  -19.3574
            13  C8x C    26.1124  -17.9302
            14  C8x C    24.8839  -15.8417
            15  C1x C    20.0522  -20.0653
            16  C8x C    26.1007  -16.5320
BOND        17
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     1   5 1
            5     2   6 2
            6     2   7 1
            7     3   8 1
            8     3   9 2
            9     4  10 1
            10    4  11 2
            11    5  12 1
            12    6  13 1
            13    7  14 2
            14    8  15 1
            15   13  16 2
            16   10  15 1
            17   14  16 1

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