KEGG   DRUG: D00814Help
Entry
D00814                      Drug                                   

Name
Doxepin hydrochloride (USP);
Sinequan (TN);
Zonalon (TN)
Product
  Generic
DOXEPIN HYDROCHLORIDE (A-S Medication Solutions LLC), DOXEPIN HYDROCHLORIDE (Aidarex Pharmaceuticals LLC), DOXEPIN HYDROCHLORIDE (AvKARE), DOXEPIN HYDROCHLORIDE (Bryant Ranch Prepack), DOXEPIN HYDROCHLORIDE (Bryant Ranch Prepack), DOXEPIN HYDROCHLORIDE (Bryant Ranch Prepack), DOXEPIN HYDROCHLORIDE (Cardinal Health), DOXEPIN HYDROCHLORIDE (Contract Pharmacy Services-PA), DOXEPIN HYDROCHLORIDE (DIRECT RX), DOXEPIN HYDROCHLORIDE (DIRECT RX), DOXEPIN HYDROCHLORIDE (H.J. Harkins Company), DOXEPIN HYDROCHLORIDE (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), DOXEPIN HYDROCHLORIDE (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), DOXEPIN HYDROCHLORIDE (Morton Grove Pharmaceuticals), DOXEPIN HYDROCHLORIDE (Mylan Institutional), DOXEPIN HYDROCHLORIDE (Mylan Pharmaceuticals), DOXEPIN HYDROCHLORIDE (PD-Rx Pharmaceuticals), DOXEPIN HYDROCHLORIDE (PD-Rx Pharmaceuticals), DOXEPIN HYDROCHLORIDE (PD-Rx Pharmaceuticals), DOXEPIN HYDROCHLORIDE (PD-Rx Pharmaceuticals), DOXEPIN HYDROCHLORIDE (Par Pharmaceutical), DOXEPIN HYDROCHLORIDE (Physicians Total Care), DOXEPIN HYDROCHLORIDE (REMEDYREPACK), DOXEPIN HYDROCHLORIDE (REMEDYREPACK), DOXEPIN HYDROCHLORIDE (REMEDYREPACK), DOXEPIN HYDROCHLORIDE (REMEDYREPACK), DOXEPIN HYDROCHLORIDE (REMEDYREPACK), DOXEPIN HYDROCHLORIDE (REMEDYREPACK), DOXEPIN HYDROCHLORIDE (Rebel Distributors Corp), DOXEPIN HYDROCHLORIDE (STAT Rx USA LLC), DOXEPIN HYDROCHLORIDE (STAT Rx USA LLC), DOXEPIN HYDROCHLORIDE (Silarx Pharmaceuticals), DOXEPIN HYDROCHLORIDE (Teva Pharmaceuticals USA), DOXEPIN HYDROCHLORIDE (Unit Dose Services)
Formula
C19H21NO. HCl
Exact mass
315.139
Mol weight
315.8371
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antidepressant
Remark
ATC code: 
Drug group: 
Comment
norepinephrine reuptake inhibitor
Interaction
Genomic biomarker: CYP2D6 [HSA:1565]
CYP inhibition: CYP2D6 [HSA:1565]
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N06 PSYCHOANALEPTICS
   N06A ANTIDEPRESSANTS
    N06AA Non-selective monoamine reuptake inhibitors
     N06AA12 Doxepin
      D00814  Doxepin hydrochloride (USP)
USP drug classification [BR:br08302]
 Antidepressants
  Tricyclics
   Doxepin
    D00814  Doxepin hydrochloride (USP)
 Anxiolytics
  Anxiolytics, Other
   Doxepin
    D00814  Doxepin hydrochloride (USP)
 Dermatological Agents
  Doxepin
   D00814  Doxepin hydrochloride (USP)
 Sleep Disorder Agents
  Sleep Disorders, Other
   Doxepin
    D00814  Doxepin hydrochloride (USP)
Cytochrome P450 interactions [BR:br08309]
 Inhbitors
  CYP2D6
   Doxepin
    D00814  Doxepin hydrochloride (USP)
BRITE hierarchy
Other DBs
CAS: 
1229-29-4
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        22
            1   X   Cl   20.8859  -12.9993
            2   C1x C    16.9400  -18.6200
            3   C8y C    16.1000  -17.5000
            4   C8y C    16.4500  -16.1700
            5   C2y C    17.7100  -15.6100
            6   O2x O    18.3400  -18.6200
            7   C8y C    18.9700  -16.2400
            8   C8y C    19.2500  -17.5700
            9   C8x C    15.4700  -15.1900
            10  C8x C    14.0700  -15.6100
            11  C8x C    13.7900  -16.9400
            12  C8x C    14.7700  -17.9200
            13  C8x C    20.5800  -17.9900
            14  C8x C    21.6300  -17.0800
            15  C8x C    21.3500  -15.7500
            16  C8x C    20.0200  -15.2600
            17  C2b C    17.7100  -14.1400
            18  C1b C    16.4500  -13.4400
            19  C1b C    15.2600  -14.1400
            20  N1c N    14.0700  -13.4400
            21  C1a C    12.8800  -14.1400
            22  C1a C    14.0700  -12.0400
BOND        23
            1     4   5 1
            2     2   6 1
            3     5   7 1
            4     3   4 1
            5     6   8 1
            6     2   3 1
            7     7   8 1
            8     4   9 2
            9     9  10 1
            10   10  11 2
            11   11  12 1
            12    3  12 2
            13    8  13 2
            14   13  14 1
            15   14  15 2
            16   15  16 1
            17    7  16 2
            18    5  17 2
            19   17  18 1
            20   18  19 1
            21   19  20 1
            22   20  21 1
            23   20  22 1

» Japanese version   » Back

DBGET integrated database retrieval system