| Entry |
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| Name |
Alfacalcidol (JAN/INN);
Alsiodol (TN)
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| Formula |
C27H44O2
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| Exact mass |
400.3341
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| Mol weight |
400.6371
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| Structure |
     |
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| Activity |
Regulator [calcium]
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| Remark |
Therapeutic category: ATC code: |
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| Comment |
Prodrug of Calcitriol [CPD: C01673]
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| Target |
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| Pathway |
hsa04961 Endocrine and other factor-regulated calcium reabsorption
hsa04978 Mineral absorption | |
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| Interaction |
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| Structure map |
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| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
3 Agents affecting metabolism
31 Vitamins
311 Vitamins A and D preparations
3112 Synthetic vitamin D preparations
D01518 Alfacalcidol (JAN/INN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A11 VITAMINS
A11C VITAMIN A AND D, INCL. COMBINATIONS OF THE TWO
A11CC Vitamin D and analogues
A11CC03 Alfacalcidol
D01518 Alfacalcidol (JAN/INN)
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Thyroid hormone like receptors
Vitamin D3 like receptor
vitamin D receptor [HSA:7421] [KO:K08539]
Alfacalcidol [ATC:A11CC03]
D01518 Alfacalcidol (JAN/INN)
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| Other DBs |
CAS: 41294-56-8 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 29
1 C1x C 22.3300 -24.5000
2 C1x C 22.3300 -25.9000
3 C2y C 23.5424 -26.6000
4 C1y C 24.7549 -25.9000
5 C1z C 24.7549 -24.5000
6 C1x C 23.5424 -23.8000
7 C1x C 26.0864 -26.3326
8 C1x C 26.9093 -25.2000
9 C1y C 26.0864 -24.0674
10 C1a C 24.7549 -23.1000
11 C2b C 23.5424 -27.9998
12 C2b C 22.3132 -28.7097
13 C2y C 22.3132 -30.1097
14 C1x C 21.1176 -30.8000
15 C1y C 21.1176 -32.2000
16 C1x C 22.3300 -32.9000
17 C1y C 23.5256 -32.2097
18 C2y C 23.5256 -30.8097
19 C2a C 24.7380 -30.1097
20 O1a O 24.7297 -32.9048
21 O1a O 19.9221 -32.8904
22 C1c C 26.5175 -22.7406
23 C1b C 27.9175 -22.7406
24 C1a C 25.7035 -21.6200
25 C1b C 28.6166 -21.5299
26 C1b C 30.0166 -21.5299
27 C1c C 30.7071 -20.3346
28 C1a C 32.1295 -20.2655
29 C1a C 29.9982 -19.1065
BOND 31
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 5 9 1
11 5 10 1 #Up
12 3 11 2
13 11 12 1
14 12 13 2
15 13 14 1
16 14 15 1
17 15 16 1
18 16 17 1
19 17 18 1
20 13 18 1
21 18 19 2
22 17 20 1 #Up
23 15 21 1 #Down
24 9 22 1
25 22 23 1
26 22 24 1 #Down
27 23 25 1
28 25 26 1
29 26 27 1
30 27 28 1
31 27 29 1
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