KEGG   DRUG: Cloperastine fendizoate
Entry
D01569                      Drug                                   
Name
Cloperastine fendizoate (JP18);
Hustazol (TN)
Formula
C20H24ClNO. C20H14O4
Exact mass
647.2439
Mol weight
648.18
Structure
Remark
Therapeutic category: 2229
ATC code: R05DB21
Chemical structure group: DG01091
Product (DG01091): D01569<JP> D01609<JP>
Efficacy
Antitussive
Comment
Diphenhydramine derivative
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R05 COUGH AND COLD PREPARATIONS
   R05D COUGH SUPPRESSANTS, EXCL. COMBINATIONS WITH EXPECTORANTS
    R05DB Other cough suppressants
     R05DB21 Cloperastine
      D01569  Cloperastine fendizoate (JP18) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  22  Respiratory organ agents
   222  Antitussives
    2229  Others
     D01569  Cloperastine fendizoate (JP18)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Cloperastine
    D01569  Cloperastine fendizoate (JP18)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01569  Cloperastine fendizoate
  D01569  Cloperastine fendizoate tablets
Other DBs
CAS: 85187-37-7
PubChem: 7848632
LigandBox: D01569
NIKKAJI: J312.035J
LinkDB
KCF data

ATOM        47
            1   C8x C    25.8434  -12.6978
            2   C8x C    25.8434  -14.0958
            3   C8x C    27.0571  -14.7949
            4   C8x C    28.2637  -14.0958
            5   C8y C    28.2637  -12.6978
            6   C8y C    27.0571  -11.9987
            7   C5a C    29.4748  -11.9996
            8   C8y C    30.6852  -12.6996
            9   C8x C    30.6785  -14.0957
            10  C8y C    31.8889  -14.7956
            11  C8y C    33.1002  -14.0975
            12  C8x C    33.1012  -12.6995
            13  C8x C    31.8909  -11.9994
            14  C6a C    27.0588  -10.6006
            15  O6a O    28.2704   -9.9031
            16  O6a O    25.8488   -9.9001
            17  O5a O    29.4760  -10.6015
            18  O1a O    34.3104  -14.7974
            19  C8y C    31.8878  -16.1937
            20  C8x C    30.6789  -16.8819
            21  C8x C    30.6779  -18.2799
            22  C8x C    31.8880  -18.9798
            23  C8x C    33.0994  -18.2818
            24  C8x C    33.1004  -16.8837
            25  C1c C    19.0338  -16.1765
            26  C8y C    17.8216  -16.8766
            27  C8y C    20.2576  -16.8766
            28  O2a O    19.0396  -14.7761
            29  C8x C    17.8216  -18.2770
            30  C8x C    16.6153  -16.1765
            31  C8x C    20.2458  -18.2770
            32  C8x C    21.4638  -16.1765
            33  C1b C    20.2576  -14.0760
            34  C8x C    16.6153  -18.9773
            35  C8x C    15.4033  -16.8766
            36  C8x C    21.4580  -18.9773
            37  C8x C    22.6760  -16.8766
            38  C8x C    15.4033  -18.2770
            39  C8y C    22.6700  -18.2770
            40  X   Cl   23.8878  -18.9833
            41  C1b C    21.4460  -14.7638
            42  N1y N    22.6369  -14.0778
            43  C1x C    23.8250  -14.7655
            44  C1x C    25.0382  -14.0668
            45  C1x C    25.0397  -12.6668
            46  C1x C    23.8516  -11.9791
            47  C1x C    22.6384  -12.6778
BOND        51
            1    20  21 1
            2    21  22 2
            3    22  23 1
            4    23  24 2
            5    24  19 1
            6     2   3 1
            7     3   4 2
            8     4   5 1
            9     5   6 2
            10    8   9 2
            11    9  10 1
            12   10  11 2
            13   11  12 1
            14   12  13 2
            15   13   8 1
            16    6   1 1
            17    6  14 1
            18   14  15 2
            19    5   7 1
            20   14  16 1
            21   10  19 1
            22    7  17 2
            23    7   8 1
            24   11  18 1
            25    1   2 2
            26   19  20 2
            27   25  26 1
            28   25  27 1
            29   25  28 1
            30   26  29 1
            31   26  30 2
            32   27  31 2
            33   27  32 1
            34   28  33 1
            35   29  34 2
            36   30  35 1
            37   31  36 1
            38   32  37 2
            39   34  38 1
            40   36  39 2
            41   35  38 2
            42   37  39 1
            43   39  40 1
            44   33  41 1
            45   41  42 1
            46   42  43 1
            47   43  44 1
            48   44  45 1
            49   45  46 1
            50   46  47 1
            51   42  47 1

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