KEGG   DRUG: GlyclopyramideHelp
Entry
D01799                      Drug                                   

Name
Glyclopyramide (JAN/INN);
Deamelin-S (TN)
Formula
C11H14ClN3O3S
Exact mass
303.0444
Mol weight
303.7652
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Antidiabetic agent
 DG01790  Sulfonamide hypoglycemic
  DG01734  Sulfonamide type sulfonylurea receptor agonist
 DG01508  Sulfonylurea receptor agonist
Remark
Therapeutic category: 
Activity
Antidiabetic
  Disease
Type 2 diabetes mellitus [DS:H00409]
Comment
Sulfonylurea
Target
ABCC8 (SUR1) [HSA:6833] [KO:K05032]
  Pathway
ABC transporters
Insulin secretion
Type II diabetes mellitus
Interaction
Drug interaction
Structure map
Sulfonamide derivatives - hypoglycemic agents
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   396  Antidiabetic agents
    3961  Sulfonylureas
     D01799  Glyclopyramide (JAN/INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  ABC transporters
   ABCC (CFTR/MRP) subfamily
    ABCC8 (sulfonylurea receptor 1)
     Glyclopyramide
      D01799  Glyclopyramide (JAN/INN)
Antidiabetics [br08361.html]
 D01799
BRITE hierarchy
Other DBs
CAS: 
631-27-6
PubChem: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        19
            1   C8x C    10.8910  -17.8271
            2   C8y C    10.8910  -19.2312
            3   C8x C    12.0845  -19.9333
            4   C8x C    13.2780  -19.2312
            5   C8y C    13.2780  -17.8271
            6   C8x C    12.0845  -17.1251
            7   X   Cl    9.6273  -19.9333
            8   S4a S    14.4996  -17.1282
            9   N1b N    15.7114  -17.8342
            10  O3c O    15.4896  -16.1383
            11  O3c O    13.5097  -16.1383
            12  C5a C    16.8961  -17.1564
            13  N1b N    18.0835  -17.8482
            14  O5a O    16.9017  -15.7504
            15  N1y N    19.2801  -17.1635
            16  C1x C    20.5834  -17.5766
            17  C1x C    21.3820  -16.4671
            18  C1x C    20.5735  -15.3648
            19  C1x C    19.2753  -15.7930
BOND        20
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     6   1 1
            7     2   7 1
            8     5   8 1
            9     8   9 1
            10    8  10 2
            11    8  11 2
            12    9  12 1
            13   12  13 1
            14   12  14 2
            15   13  15 1
            16   15  16 1
            17   16  17 1
            18   17  18 1
            19   18  19 1
            20   15  19 1

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