KEGG   DRUG: D01799Help
Entry
D01799                      Drug                                   

Name
Glyclopyramide (JAN/INN);
Deamelin-S (TN)
Formula
C11H14ClN3O3S
Exact mass
303.0444
Mol weight
303.7652
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antidiabetic [DS:H00409]
Remark
Therapeutic category: 
Comment
Sulfonylurea
Target
sulfonylurea receptor 1 agonist [HSA:6833] [KO:K05032]
  Pathway
hsa02010  ABC transporters
hsa04911  Insulin secretion
hsa04930  Type II diabetes mellitus  
 
Interaction
Drug interaction
Structure map
Sulfonamide derivatives - hypoglycemic agents
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   396  Antidiabetic agents
    3961  Sulfonylureas
     D01799  Glyclopyramide (JAN/INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  ABC transporters
   ABCC (CFTR/MRP) subfamily
    ABCC8 (sulfonylurea receptor 1)
     Glyclopyramide
      D01799  Glyclopyramide (JAN/INN)
BRITE hierarchy
Other DBs
CAS: 
631-27-6
PubChem: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        19
            1   N1b N    31.4133  -14.1223
            2   C5a C    32.6238  -14.8231
            3   N1b N    33.8343  -14.1223
            4   N1y N    35.0448  -14.8231
            5   O5a O    32.6238  -16.2248
            6   C1x C    36.3775  -14.3901
            7   C1x C    37.1983  -15.5228
            8   C1x C    36.3745  -16.6532
            9   C1x C    35.0450  -16.2193
            10  S4a S    30.1987  -14.8218
            11  C8x C    26.5671  -15.5226
            12  C8y C    26.5671  -16.9242
            13  C8x C    27.7839  -17.6250
            14  C8x C    28.9936  -16.9242
            15  C8y C    28.9936  -15.5226
            16  C8x C    27.7839  -14.8218
            17  X   Cl   25.3536  -17.6255
            18  O3c O    29.4907  -13.6041
            19  O3c O    30.8924  -16.0323
BOND        20
            1     2   5 2
            2     1  10 1
            3     2   3 1
            4     1   2 1
            5     3   4 1
            6     4   6 1
            7     6   7 1
            8    11  12 2
            9    12  13 1
            10   13  14 2
            11   14  15 1
            12   15  16 2
            13   16  11 1
            14    7   8 1
            15   12  17 1
            16   15  10 1
            17    8   9 1
            18   10  18 2
            19    9   4 1
            20   10  19 2

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