KEGG   DRUG: D02125Help
Entry
D02125                      Drug                                   

Name
Chloroquine phosphate (USP);
Aralen (TN)
Product
  Generic
Formula
C18H26ClN3. 2H3PO4
Exact mass
515.1353
Mol weight
515.8625
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anti-amebic;
Antimalarial;
Suppressant [lupus erythematosus] [DS:H00360 H00361]
Remark
ATC code: 
Drug group: 
Comment
Indications: Malaria, Amebiasis
Chloroquine should be administered with caution to patients having Glucose-6-phosphate dehydrogenase (G6PD) deficiency [DS:H00668].
Interaction
Genomic biomarker: G6PD [HSA:2539]
Drug interaction
Structure map
Quinolines
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 P ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
  P01 ANTIPROTOZOALS
   P01B ANTIMALARIALS
    P01BA Aminoquinolines
     P01BA01 Chloroquine
      D02125  Chloroquine phosphate (USP)
USP drug classification [BR:br08302]
 Antiparasitics
  Antiprotozoals
   Chloroquine
    D02125  Chloroquine phosphate (USP)
Antiinfectives [BR:br08307]
 Antiparasitics
  Antmalarials
   Others
    Aminoquinolines
     Chloroquine
      D02125  Chloroquine phosphate (USP)
BRITE hierarchy
Other DBs
CAS: 
50-63-5
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        32
            1   P1b P    29.7482  -17.6335
            2   O1c O    29.7482  -16.2345
            3   O1c O    28.3494  -17.6335
            4   O1c O    31.1473  -17.6335
            5   O1c O    29.7482  -19.0325
            6   N1b N    22.7560  -14.2251
            7   C1c C    23.9642  -13.5307
            8   C1b C    25.1722  -14.2309
            9   C1a C    23.9700  -12.1300
            10  C1b C    26.3863  -13.5364
            11  C1b C    27.5884  -14.2368
            12  N1c N    28.8024  -13.5482
            13  C1b C    30.0104  -14.2484
            14  C1b C    28.7381  -12.1474
            15  C1a C    31.2186  -13.5539
            16  C1a C    29.9463  -11.4530
            17  C8y C    22.7537  -15.6517
            18  C8y C    21.5199  -16.3617
            19  C8y C    21.5179  -17.7586
            20  N5x N    22.7267  -18.4588
            21  C8x C    23.9605  -17.7489
            22  C8x C    23.9625  -16.3519
            23  C8x C    20.3101  -15.6632
            24  C8x C    19.1003  -16.3617
            25  C8y C    19.1003  -17.7586
            26  C8x C    20.3101  -18.4571
            27  X   Cl   17.8885  -18.4583
            28  P1b P    29.7482  -17.6335
            29  O1c O    29.7482  -16.2345
            30  O1c O    28.3494  -17.6335
            31  O1c O    31.1473  -17.6335
            32  O1c O    29.7482  -19.0325
BOND        31
            1     6   7 1
            2     7   8 1
            3     7   9 1
            4     8  10 1
            5    10  11 1
            6    11  12 1
            7    12  13 1
            8    12  14 1
            9    13  15 1
            10   14  16 1
            11    6  17 1
            12   17  18 1
            13   18  19 2
            14   19  20 1
            15   20  21 2
            16   21  22 1
            17   17  22 2
            18   18  23 1
            19   23  24 2
            20   24  25 1
            21   25  26 2
            22   26  19 1
            23   25  27 1
            24    1   2 2
            25    1   3 1
            26    1   4 1
            27    1   5 1
            28   28  29 2
            29   28  30 1
            30   28  31 1
            31   28  32 1
BRACKET     1    27.0200  -19.5300   27.0200  -15.4700
            1    32.4100  -15.4700   32.4100  -19.5300
            1  2
 ORIGINAL  1    1   2   3   4   5
 REPEAT    1   28  29  30  31  32

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