KEGG   DRUG: D02469Help
Entry
D02469                      Drug                                   

Name
Temafloxacin hydrochloride (USAN);
Omniflox (TN)
Formula
C21H18F3N3O3. HCl
Exact mass
453.1067
Mol weight
453.8421
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial [microbial DNA topoisomerase inhibitor]
Remark
ATC code: 
Drug group: 
Target
DNA gyrase inhibitor [KO:K02469 K02470];
topoisomerase IV inhibitor [KO:K02621 K02622]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01M QUINOLONE ANTIBACTERIALS
    J01MA Fluoroquinolones
     J01MA05 Temafloxacin
      D02469  Temafloxacin hydrochloride (USAN)
Antiinfectives [BR:br08307]
 Antibacterials
  Nucleic acid synthesis inhibitor
   type II topoisomerase (DNA gyrase, topoisomerase IV) inhibitor
    Fluoroquinolones
     Temafloxacin
      D02469  Temafloxacin hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
105784-61-0
PubChem: 
DrugBank: 
LigandBox: 
LinkDB All DBs
KCF data Show

ATOM        31
            1   C8y C    19.1923  -14.8030
            2   C8x C    20.4064  -15.5035
            3   C8y C    19.1923  -13.4020
            4   C8x C    20.4531  -12.7016
            5   N4y N    22.8348  -15.5035
            6   C8y C    21.6206  -14.8030
            7   C8y C    21.6206  -13.4488
            8   C8y C    22.8348  -12.7483
            9   C8y C    24.0489  -13.4020
            10  C8x C    24.0489  -14.8030
            11  C6a C    25.2631  -12.7016
            12  O6a O    25.2631  -11.3006
            13  O6a O    26.4772  -13.4020
            14  O5x O    22.8348  -11.3473
            15  X   F    17.9782  -12.7016
            16  N1y N    17.9782  -15.5035
            17  C1x C    17.9782  -16.9044
            18  C1x C    16.7639  -17.6049
            19  N1x N    15.5498  -16.9044
            20  C1y C    15.5498  -15.5035
            21  C1x C    16.7639  -14.8030
            22  C1a C    14.3367  -14.8028
            23  C8y C    22.8348  -16.9044
            24  C8x C    21.6215  -17.6049
            25  C8x C    21.6215  -19.0058
            26  C8y C    22.8348  -19.7063
            27  C8x C    24.0480  -19.0058
            28  C8y C    24.0480  -17.6049
            29  X   F    25.2619  -16.9040
            30  X   F    22.8348  -21.1073
            31  X   Cl   29.8863  -15.9705
BOND        33
            1     1   3 1
            2     3   4 2
            3     4   7 1
            4     5   6 1
            5     6   7 2
            6     7   8 1
            7     8   9 1
            8     9  10 2
            9    10   5 1
            10    9  11 1
            11   11  12 2
            12   11  13 1
            13    8  14 2
            14    6   2 1
            15    3  15 1
            16    2   1 2
            17    1  16 1
            18   16  17 1
            19   17  18 1
            20   18  19 1
            21   19  20 1
            22   20  21 1
            23   16  21 1
            24   20  22 1
            25    5  23 1
            26   23  24 2
            27   24  25 1
            28   25  26 2
            29   26  27 1
            30   27  28 2
            31   23  28 1
            32   28  29 1
            33   26  30 1

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