KEGG   DRUG: Temafloxacin hydrochlorideHelp
Entry
D02469                      Drug                                   

Name
Temafloxacin hydrochloride (USAN);
Omniflox (TN)
Formula
C21H18F3N3O3. HCl
Exact mass
453.1067
Mol weight
453.8421
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Antibacterial
 DG01550  Quinolone
  DG01549  Fluoroquinolone
Other
 DG01529  Topoisomerase inhibitor
  DG01528  Topoisomerase IV inhibitor
Remark
ATC code: 
Activity
Antibacterial, Nucleic acid biosynthesis inhibitor
Comment
Fluoroquinolones
Target
DNA gyrase [KO:K02469 K02470];
topoisomerase IV [KO:K02621 K02622]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01M QUINOLONE ANTIBACTERIALS
    J01MA Fluoroquinolones
     J01MA05 Temafloxacin
      D02469  Temafloxacin hydrochloride (USAN)
Antiinfectives [BR:br08307]
 Antibacterials
  Nucleic acid synthesis inhibitor
   type II topoisomerase (DNA gyrase, topoisomerase IV) inhibitor
    Fluoroquinolones
     Temafloxacin
      D02469  Temafloxacin hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
105784-61-0
PubChem: 
DrugBank: 
LigandBox: 
LinkDB All DBs
KCF data Show

ATOM        31
            1   C8y C    19.1923  -14.8030
            2   C8x C    20.4064  -15.5035
            3   C8y C    19.1923  -13.4020
            4   C8x C    20.4531  -12.7016
            5   N4y N    22.8348  -15.5035
            6   C8y C    21.6206  -14.8030
            7   C8y C    21.6206  -13.4488
            8   C8y C    22.8348  -12.7483
            9   C8y C    24.0489  -13.4020
            10  C8x C    24.0489  -14.8030
            11  C6a C    25.2631  -12.7016
            12  O6a O    25.2631  -11.3006
            13  O6a O    26.4772  -13.4020
            14  O5x O    22.8348  -11.3473
            15  X   F    17.9782  -12.7016
            16  N1y N    17.9782  -15.5035
            17  C1x C    17.9782  -16.9044
            18  C1x C    16.7639  -17.6049
            19  N1x N    15.5498  -16.9044
            20  C1y C    15.5498  -15.5035
            21  C1x C    16.7639  -14.8030
            22  C1a C    14.3367  -14.8028
            23  C8y C    22.8348  -16.9044
            24  C8x C    21.6215  -17.6049
            25  C8x C    21.6215  -19.0058
            26  C8y C    22.8348  -19.7063
            27  C8x C    24.0480  -19.0058
            28  C8y C    24.0480  -17.6049
            29  X   F    25.2619  -16.9040
            30  X   F    22.8348  -21.1073
            31  X   Cl   29.8863  -15.9705
BOND        33
            1     1   3 1
            2     3   4 2
            3     4   7 1
            4     5   6 1
            5     6   7 2
            6     7   8 1
            7     8   9 1
            8     9  10 2
            9    10   5 1
            10    9  11 1
            11   11  12 2
            12   11  13 1
            13    8  14 2
            14    6   2 1
            15    3  15 1
            16    2   1 2
            17    1  16 1
            18   16  17 1
            19   17  18 1
            20   18  19 1
            21   19  20 1
            22   20  21 1
            23   16  21 1
            24   20  22 1
            25    5  23 1
            26   23  24 2
            27   24  25 1
            28   25  26 2
            29   26  27 1
            30   27  28 2
            31   23  28 1
            32   28  29 1
            33   26  30 1

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