KEGG   DRUG: D02481Help
Entry
D02481                      Drug                                   

Name
Artemisinin (INN);
Qing Hau Sau
Formula
C15H22O5
Exact mass
282.1467
Mol weight
282.3322
Structure
Mol fileKCF fileDB searchJmolKegDraw
Source
Artemisia annua [TAX:35608], Artemisia caruifolia var. apiacea [TAX:262982]
Activity
Antimalarial [DS:H00361]
Remark
Same as: 
ATC code: 
Comment
Artemisinin [DR:D02481] related compound
Target
Plasmodium falciparum sarcoplasmic/endoplasmic-reticulum Ca2+-ATPase (SERCA) inhibitor
Interaction
CYP induction: CYP2C19 [HSA:1557]
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 P ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
  P01 ANTIPROTOZOALS
   P01B ANTIMALARIALS
    P01BE Artemisinin and derivatives, plain
     P01BE01 Artemisinin
      D02481  Artemisinin (INN)
Antiinfectives [BR:br08307]
 Antiparasitics
  Antmalarials
   sarcoplasmic/endoplasmic-reticulum Ca2+-ATPase (SERCA) inhibitor
    Artemisinin and derivatives
     Artemisinin [ATC:P01BE01]
      D02481  Artemisinin (INN)
BRITE hierarchy
Other DBs
CAS: 
63968-64-9
PubChem: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        20
            1   C1z C    27.8553  -18.0523
            2   C1y C    26.6485  -18.7461
            3   C1y C    29.0737  -18.7577
            4   C1y C    27.8612  -16.6649
            5   O2x O    26.2637  -17.9240
            6   O2x O    25.3426  -18.2331
            7   O7x O    26.6544  -20.1569
            8   C1y C    29.0737  -20.1569
            9   C1x C    30.2746  -18.0581
            10  C1y C    29.0737  -15.9652
            11  C1x C    27.1149  -15.6388
            12  O2x O    26.2696  -16.5307
            13  C1z C    24.9287  -16.8979
            14  C7x C    27.8612  -20.8564
            15  C1a C    30.2805  -20.8507
            16  C1x C    30.2746  -16.6649
            17  C1a C    29.0737  -14.5720
            18  C1x C    25.7158  -15.6096
            19  C1a C    23.5470  -16.8979
            20  O6a O    27.8669  -22.2497
BOND        23
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     1   5 1 #Down
            5     2   6 1
            6     2   7 1
            7     3   8 1
            8     3   9 1
            9     4  10 1
            10    4  11 1
            11    5  12 1
            12    6  13 1
            13    7  14 1
            14    8  15 1 #Up
            15    9  16 1
            16   10  17 1 #Down
            17   11  18 1
            18   13  19 1 #Up
            19   14  20 2
            20    8  14 1
            21   10  16 1
            22   13  12 1 #Down
            23   13  18 1

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