KEGG   DRUG: BelimumabHelp
Entry
D03068                      Drug                                   

Name
Belimumab (USAN);
Belimumab (genetical recombination) (JAN);
Benlysta (TN);
LymphoStat-B (TN)
Product
Formula
C6714H10428N1816O2102S52
Exact mass
151791.04
Mol weight
151884.9241
Remark
Therapeutic category: 3999
ATC code: L04AA26
Product: D03068<JP/US>
Efficacy
Immunosuppressant, Anti-BLyS antibody
  Disease
Systemic lupus erythematosus [DS:H00080]
Comment
Monoclonal antibody
Target
TNFSF13B (BAFF, CD257) [HSA:10673] [KO:K05476]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04064  NF-kappa B signaling pathway
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L04 IMMUNOSUPPRESSANTS
   L04A IMMUNOSUPPRESSANTS
    L04AA Selective immunosuppressants
     L04AA26 Belimumab
      D03068  Belimumab (USAN) <JP/US>
USP drug classification [BR:br08302]
 Immunological Agents
  Immunomodulators
   Belimumab
    D03068  Belimumab (USAN)
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   399  Miscellaneous
    3999  Others
     D03068  Belimumab (USAN); Belimumab (genetical recombination) (JAN)
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokines
   Tumor necrosis factors
    TNFSF13B (BAFF, CD257)
     D03068  Belimumab (USAN) <JP/US>
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D03068
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D03068
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D03068
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D03068
Pharmacogenomic biomarkers in FDA drug labels [br08341.html]
 Polymorphisms and germline mutations
  D03068
BRITE hierarchy
Other DBs
CAS: 356547-88-1
PubChem: 17397223
NIKKAJI: J2.313.545K
LinkDB All DBs

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