KEGG   DRUG: NicotineHelp
Entry
D03365                      Drug                                   

Name
Nicotine (USP);
Habitrol (TN)
Product
  Other
Formula
C10H14N2
Exact mass
162.1157
Mol weight
162.2316
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Other
 DG01718  Drugs for addictive disorder
  DG01715  Drugs for nicotine dependence
Cyp substrate
 DG01892  CYP1A2 substrate
 DG01638  CYP2A6 substrate
Remark
Same as: 
Therapeutic category: 
ATC code: 
Chemical group: 
Activity
Smoking cessation adjunct
Metabolism
Enzyme: CYP1A2 [HSA:1544], CYP2A6 [HSA:1548]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N07 OTHER NERVOUS SYSTEM DRUGS
   N07B DRUGS USED IN ADDICTIVE DISORDERS
    N07BA Drugs used in nicotine dependence
     N07BA01 Nicotine
      D03365  Nicotine (USP)
USP drug classification [BR:br08302]
 Anti-Addiction/Substance Abuse Treatment Agents
  Smoking Cessation Agents
   Nicotine
    D03365  Nicotine (USP)
Therapeutic category of drugs in Japan [BR:br08301]
 7  Agents not mainly for therapeutic purpose
  79  Other agents not mainly for therapeutic purpose
   799  Miscellaneous
    7990  Miscellaneous
     D03365  Nicotine (USP)
Classification of Japanese OTC drugs [BR:br08313]
 Stop smoking aid
  77 Stop smoking aid
   D03365  Nicotine (USP)
Risk category of Japanese OTC drugs [BR:br08312]
 First-class OTC drugs
  Inorganic and organic chemicals
   Nicotine
    D03365  Nicotine (USP)
 Designated second-class OTC drugs
  Inorganic and organic chemicals
   Nicotine
    D03365  Nicotine (USP)
 Second-class OTC drugs
  Inorganic and organic chemicals
   Nicotine
    D03365  Nicotine (USP)
Cytochrome P450 interactions [BR:br08309]
 CYP substrates
  CYP1A2
   Nicotine
    D03365  Nicotine (USP)
  CYP2A6
   Nicotine
    D03365  Nicotine (USP)
Phytochemicals used as drugs [BR:br08306]
 Alkaloids
  Alkaloids derived from nicotinic acid
   Pyridine alkaloids
    D03365  Nicotine (USP)
Rx-to-OTC switch list in the USA [br08315.html]
 D03365
Rx-to-OTC switch list in Japan [br08314.html]
 D03365
BRITE hierarchy
Other DBs
CAS: 
54-11-5
PubChem: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        12
            1   C8x C    29.1341  -17.6496
            2   C8x C    29.1341  -19.0503
            3   N5x N    30.3471  -19.7507
            4   C8x C    31.5602  -19.0503
            5   C8y C    31.5602  -17.6496
            6   C8x C    30.3471  -16.9493
            7   C1y C    32.7920  -16.9383
            8   C1x C    34.1270  -17.3204
            9   C1x C    34.9074  -16.1695
            10  C1x C    34.0540  -15.0718
            11  N1y N    32.7463  -15.5441
            12  C1a C    31.5702  -14.7465
BOND        13
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     7   5 1 #Up
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12    7  11 1
            13   11  12 1

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