KEGG   DRUG: D04300Help
Entry
D04300                      Drug                                   

Name
Ganaxolone (USAN/INN)
Formula
C22H36O2
Exact mass
332.2715
Mol weight
332.52
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Treatment of epilepsy and migraine
Comment
Allopregnanolone [CPD:C15484] analogue
Target
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04727  GABAergic synapse  
 
Brite
Target-based classification of drugs [BR:br08310]
 Ion channels
  Cys-loop superfamily
   GABA-A
    GABAA-receptor
     Ganaxolone
      D04300  Ganaxolone (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
38398-32-2
PubChem: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        24
            1   C1x C    38.1743  -26.7423
            2   C1z C    38.1743  -28.1094
            3   C1x C    39.3363  -28.7930
            4   C1y C    40.5668  -28.1094
            5   C1z C    40.5668  -26.7423
            6   C1x C    39.3363  -26.0587
            7   C1x C    41.7288  -28.7930
            8   C1x C    42.8909  -28.1094
            9   C1y C    42.8909  -26.7423
            10  C1y C    41.7288  -26.0587
            11  C1y C    44.1213  -26.0587
            12  C1z C    44.1213  -24.6916
            13  C1x C    42.8909  -24.0080
            14  C1x C    41.7288  -24.6916
            15  C1a C    40.5668  -25.3751
            16  C1a C    44.1213  -23.3244
            17  C1a C    36.8071  -28.1094
            18  O1a O    37.8325  -29.4082
            19  C1x C    46.5138  -26.0587
            20  C1x C    46.5138  -24.6916
            21  C1y C    45.2834  -24.0080
            22  C5a C    45.2666  -22.6410
            23  C1a C    44.0870  -21.9792
            24  O5a O    46.4544  -21.9354
BOND        27
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    9  11 1
            13   12  13 1
            14   13  14 1
            15   10  14 1
            16    5  15 1 #Up
            17   12  16 1 #Up
            18    2  17 1 #Up
            19    2  18 1 #Down
            20   11  19 1
            21   19  20 1
            22   20  21 1
            23   21  22 1 #Up
            24   22  23 1
            25   22  24 2
            26   21  12 1
            27   12  11 1

» Japanese version   » Back

DBGET integrated database retrieval system