KEGG   DRUG: LaronidaseHelp
Entry
D04670                      Drug                                   

Name
Laronidase (USAN);
Laronidase (genetical recombination) (JAN);
Aldurazyme (TN)
Product
Formula
C3567H5645N921O1261S12P4
Exact mass
82067.1507
Mol weight
82116.0773
Sequence
AEAPHLVHVD AARALWPLRR FWRSTGFCPP LPHSQADQYV LSWDQQLNLA YVGAVPHRGI
KQVRTHWLLE LVTTRGSTGR GLSYNFTHLD GYLDLLRENQ LLPGFELMGS ASGHFTDFED
KQQVFEWKDL VSSLARRYIG RYGLAHVSKW NFETWNEPDH HDFDNVSMTM QGFLNYYDAC
SEGLRAASPA LRLGGPGDSF HTPPRSPLSW GLLRHCHDGT NFFTGEAGVR LDYISLHRKG
ARSSISILEQ EKVVAQQIRQ LFPKFADTPI YNDEADPLVG WSLPQPWRAD VTYAAMVVKV
IAQHQNLLLA NTTSAFPYAL LSNDNAFLSY HPHPFAQRTL TARFQVNNTR PPHVQLLRKP
VLTAMGLLAL LDEEQLWAEV SQAGTVLDSN HTVGVLASAH RPQGPADAWR AAVLIYASDD
TRAHPNRSVA VTLRLRGVPP GPGLVYVTRY LDNGLCSPDG EWRRLGRPVF PTAEQFRRMR
AAEDPVAAAP RPLPAGGRLT LRPALRLPSL LLVHVCARPE KPPGQVTRLR ALPLTQGQLV
LVWSDEHVGS KCLWTYEIQF SQDGKAYTPV SRKPSTFNLF VFSPDTGAVS GSYRVRALDY
WARPGPFSDP VPYLEVPVPR GPPSPGNP
  Type
Peptide
Remark
Therapeutic category: 
ATC code: 
Efficacy
Enzyme replenisher (alpha-L-iduronidase)
  Disease
Mucopolysaccharidosis I (MPS I) [DS:H00128]
Comment
alpha-L-iduronidase [HSA:3425] [KO:K01217] [EC:3.2.1.76]
Enzyme replacement in Mucopolysaccharidosis I (MPS I)
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A16 OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
   A16A OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
    A16AB Enzymes
     A16AB05 Laronidase
      D04670  Laronidase (USAN)
USP drug classification [BR:br08302]
 Genetic or Enzyme Disorder: Replacement, Modifiers, Treatment
  Laronidase
   D04670  Laronidase (USAN)
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   395  Enzyme preparations
    3959  Others
     D04670  Laronidase (USAN); Laronidase (genetical recombination) (JAN)
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D04670
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D04670
Orphan drugs in the USA [br08355.html]
 Orphan drugs in the USA
  D04670
BRITE hierarchy
Other DBs
CAS: 
210589-09-6
PubChem: 
DrugBank: 
LinkDB All DBs

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