KEGG   DRUG: D05350Help
Entry
D05350                      Drug                                   

Name
Panitumumab (genetical recombination) (JAN);
Panitumumab (USAN/INN);
Vectibix (TN)
Product
Activity
Antineoplastic;
Treatment of EGF expressing tumors [DS:H00020]
Remark
Therapeutic category: 
ATC code: 
Comment
Monoclonal antibody
Target
epidermal growth factor receptor (EGFR) [HSA:1956] [KO:K04361]
  Pathway
hsa04010  MAPK signaling pathway
hsa04012  ErbB signaling pathway
hsa04020  Calcium signaling pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa05200  Pathways in cancer  
 
Interaction
Genomic biomarker: EGFR [HSA:1956], KRAS [HSA:3845]
Drug interaction
Structure map
Antineoplastics - protein kinases inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01X OTHER ANTINEOPLASTIC AGENTS
    L01XC Monoclonal antibodies
     L01XC08 Panitumumab
      D05350  Panitumumab (genetical recombination) (JAN); Panitumumab (USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 4  Agents affecting cellular function
  42  Antineoplastics
   429  Miscellaneous
    4291  Other Antitumors
     D05350  Panitumumab (genetical recombination) (JAN); Panitumumab (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Cytokine receptors
  Receptor tyrosine kinase
   RTK class I (EGF receptor family)
    EGFR tyrosine kinase
     Panitumumab
      D05350  Panitumumab (genetical recombination) (JAN); Panitumumab (USAN/INN)
Antineoplastics [BR:br08308]
 Molecularly targeted agents
  Monoclonal antibody
   Panitumumab
    D05350  Panitumumab (genetical recombination) (JAN); Panitumumab (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
339177-26-3
PubChem: 
NIKKAJI: 
LinkDB All DBs

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