KEGG   DRUG: D05868Help
Entry
D05868                      Drug                                   

Name
Sodium phenylbutyrate (JAN/USAN);
Buphenyl (TN)
Product
  Generic
Formula
C10H11O2. Na
Exact mass
186.0657
Mol weight
186.1829
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihyperammonemic [DS:H00164 H00185 H00186 H00187 H01028 H01032]
Remark
ATC code: 
Comment
Prodrug, active substance: Phenylacetate [CPD:C07086]
Indication: urea cycle disorders (decreased elevated plasma ammonia glutamine levels)
Interaction
Genomic biomarker: NAGS [HSA:162417], CPS [HSA:1373], ASS [HSA:445], OTC [HSA:5009], ASL [HSA:435], ARG [HSA:383 384]
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A16 OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
   A16A OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
    A16AX Various alimentary tract and metabolism products
     A16AX03 Sodium phenylbutyrate
      D05868  Sodium phenylbutyrate (JAN/USAN)
USP drug classification [BR:br08302]
 Enzyme Replacement/Modifiers
  Sodium phenylbutyrate
   D05868  Sodium phenylbutyrate (JAN/USAN)
BRITE hierarchy
Other DBs
CAS: 
1716-12-7
PubChem: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        13
            1   Z   Na   13.8833  -28.3419 #+
            2   C8x C     8.1900  -28.3500
            3   C8x C     8.1900  -29.7500
            4   C8x C     9.4024  -30.4500
            5   C8x C    10.6149  -29.7500
            6   C8x C    10.6149  -28.3500
            7   C8y C     9.4024  -27.6500
            8   C1b C     9.4024  -26.2502
            9   C1b C    10.5980  -25.5598
            10  C1b C    11.7852  -26.2452
            11  C6a C    12.9766  -25.5572
            12  O6a O    14.1659  -26.2439 #-
            13  O6a O    12.9767  -24.1503
BOND        12
            1     2   3 2
            2     3   4 1
            3     4   5 2
            4     5   6 1
            5     6   7 2
            6     2   7 1
            7     7   8 1
            8     8   9 1
            9     9  10 1
            10   10  11 1
            11   11  12 1
            12   11  13 2

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