KEGG   DRUG: TemozolomideHelp
Entry
D06067                      Drug                                   

Name
Temozolomide (JAN/USAN/INN);
Temodal (TN);
Temodar (TN)
Product
  Generic
Formula
C6H6N6O2
Exact mass
194.0552
Mol weight
194.1508
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Antineoplastic
 DG01677  Alkylating agent
Remark
Therapeutic category: 
ATC code: 
Chemical group: 
Efficacy
Antineoplastic, Alkylating agent
  Disease
Glioblastoma [DS:H00042]
Target
DNA
Interaction
Drug interaction
Structure map
Antineoplastics - alkylating agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01A ALKYLATING AGENTS
    L01AX Other alkylating agents
     L01AX03 Temozolomide
      D06067  Temozolomide (JAN/USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 4  Agents affecting cellular function
  42  Antineoplastics
   421  Alkylating agents
    4219  Others
     D06067  Temozolomide (JAN/USAN/INN)
Target-based classification of drugs [BR:br08310]
 Others
  Nucleic acid
   DNA
    Temozolomide
     D06067  Temozolomide (JAN/USAN/INN)
Antineoplastics [br08340.html]
 D06067
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D06067
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D06067
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D06067
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D06067
Orphan drugs in the USA [br08355.html]
 Orphan drugs in the USA
  D06067
BRITE hierarchy
Other DBs
CAS: 
85622-93-1
PubChem: 
ChEBI: 
ChEMBL: 
DrugBank: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        14
            1   N5x N    15.4700  -20.9300
            2   N4y N    15.4700  -22.3300
            3   C8y C    16.6824  -23.0300
            4   N4y N    17.8949  -22.3300
            5   C8y C    17.8949  -20.9300
            6   N5x N    16.6824  -20.2300
            7   C8x C    19.2264  -22.7626
            8   N5x N    20.0493  -21.6300
            9   C8y C    19.2264  -20.4974
            10  O5x O    16.6824  -24.4298
            11  C1a C    14.2576  -23.0300
            12  C5a C    19.6575  -19.1706
            13  O5a O    21.0369  -18.8774
            14  N1a N    18.7311  -18.1415
BOND        15
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 2
            7     4   7 1
            8     7   8 2
            9     8   9 1
            10    5   9 2
            11    3  10 2
            12    2  11 1
            13    9  12 1
            14   12  13 2
            15   12  14 1

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