KEGG   DRUG: LiraglutideHelp
Entry
D06404                      Drug                                   

Name
Liraglutide (USAN/INN);
Liraglutide (genetical recombination) (JAN);
Victoza (TN)
Product
Formula
C172H265N43O51
Exact mass
3748.9465
Mol weight
3751.202
Sequence
His Ala Glu Gly Thr Phe Thr Ser Asp Val Ser Ser Tyr Leu Glu Gly
Gln Ala Ala Lys Glu Phe Ile Ala Trp Leu Val Arg Gly Arg Gly
(-Glu combined: 20)
  Type
Peptide
Class
Antidiabetic agent
 DG01493  GLP-1 receptor agonist
Unclassified
 DG02044  Hypoglycemics
  DG01493  GLP-1 receptor agonist
Remark
Therapeutic category: 
ATC code: 
Efficacy
Antidiabetic, Glucagon-like peptide 1 (GLP-1) receptor agonist
  Disease
Type 2 diabetes mellitus [DS:H00409]
Comment
Human glucagon-like peptide 1 (GLP-1) [CPD:C16048] analog
Adjunctive thrapy to improve glycemic control, with diet and exercise in patients with type II diabetes
Target
GLP1R [HSA:2740] [KO:K04581]
  Pathway
Neuroactive ligand-receptor interaction
Insulin secretion
Metabolism
Enzyme: DPP4 [HSA:1803], MME [HSA:4311]
Interaction
Drug interaction
Structure map
Antidiabetics
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A10 DRUGS USED IN DIABETES
   A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
    A10BJ Glucagon-like peptide-1 receptor (GLP-1) analogues
     A10BJ02 Liraglutide
      D06404  Liraglutide (USAN/INN)
USP drug classification [BR:br08302]
 Blood Glucose Regulators
  Antidiabetic Agents
   Liraglutide
    D06404  Liraglutide (USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  24  Hormones
   249  Miscellaneous
    2499  Others
     D06404  Liraglutide (USAN/INN); Liraglutide (genetical recombination) (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Secretin receptor family
   Glucagon
    glucagon-like peptide 1 receptor
     Liraglutide
      D06404  Liraglutide (USAN/INN)
Antidiabetics [br08361.html]
 D06404
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D06404
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D06404
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D06404
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D06404
BRITE hierarchy
Other DBs
CAS: 
204656-20-2
PubChem: 
ChEBI: 
NIKKAJI: 
LinkDB All DBs

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