KEGG   DRUG: D06611Help
Entry
D06611                      Drug                                   
Name
Lexatumumab (USAN/INN)
Formula
C6346H9832N1720O2002S42
Exact mass
143510.869
Mol weight
143599.0211
Activity
Treatment of cancer
Comment
agonistic monoclonal antibody
Target
CD262 (TRAIL-R2) agonist [HSA:8795] [KO:K04722]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04115  p53 signaling pathway
hsa04210  Apoptosis
hsa04650  Natural killer cell mediated cytotoxicity  
 
Brite
Target-based classification of drugs [BR:br08310]
 Cytokine receptors
  TNF receptor family
   TNFRSF10B (CD262) [HSA:8795] [KO:K04722]
    Lexatumumab
     D06611  Lexatumumab (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
845816-02-6
PubChem: 
NIKKAJI: 

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