KEGG   DRUG: D07118Help
Entry
D07118                      Drug                                   

Name
Glisoxepide (INN)
Formula
C20H27N5O5S
Exact mass
449.1733
Mol weight
449.5239
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
ATC code: 
Target
sulfonylurea receptor 1 agonist [HSA:6833] [KO:K05032]
  Pathway
hsa02010  ABC transporters
hsa04911  Insulin secretion
hsa04930  Type II diabetes mellitus  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A10 DRUGS USED IN DIABETES
   A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
    A10BB Sulfonamides, urea derivatives
     A10BB11 Glisoxepide
      D07118  Glisoxepide (INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  ABC transporters
   ABCC (CFTR/MRP) subfamily
    ABCC8 (sulfonylurea receptor 1) [HSA:6833] [KO:K05032]
     Glisoxepide [ATC:A10BB11]
      D07118  Glisoxepide (INN)
BRITE hierarchy
Other DBs
CAS: 
25046-79-1
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        31
            1   C8x C    19.3900  -18.2700
            2   C8y C    19.3900  -19.6700
            3   C8x C    20.5800  -20.3000
            4   C8x C    21.7700  -19.6700
            5   C8y C    21.7700  -18.2700
            6   C8x C    20.5800  -17.5700
            7   S4a S    22.9600  -17.5700
            8   N1b N    24.1500  -18.2700
            9   C5a C    25.3400  -17.5700
            10  N1b N    26.5300  -18.2700
            11  O3c O    23.8000  -16.1000
            12  O3c O    21.9800  -16.1000
            13  O5a O    25.4100  -16.3800
            14  C1b C    18.1776  -20.3700
            15  C1b C    16.9651  -19.6700
            16  N1b N    15.7527  -20.3700
            17  C5a C    14.5403  -19.6700
            18  C8y C    13.3278  -20.3700
            19  C1x C    27.8000  -15.8747
            20  C1x C    28.8967  -15.0110
            21  C1x C    30.2621  -15.3224
            22  C1x C    30.8640  -16.5756
            23  N1y N    27.8000  -17.2837
            24  C1x C    30.2630  -17.8429
            25  C1x C    28.8967  -18.1545
            26  O5a O    14.5403  -18.2701
            27  C8x C    12.0947  -19.6578
            28  C8y C    11.0921  -20.7776
            29  O2x O    11.6250  -21.9798
            30  N5x N    13.1176  -21.8400
            31  C1a C     9.6800  -20.5544
BOND        33
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    7  11 2
            12    7  12 2
            13    9  13 2
            14    2  14 1
            15   14  15 1
            16   15  16 1
            17   16  17 1
            18   17  18 1
            19   21  22 1
            20   19  23 1
            21   22  24 1
            22   20  21 1
            23   23  25 1
            24   19  20 1
            25   24  25 1
            26   10  23 1
            27   17  26 2
            28   18  27 1
            29   27  28 2
            30   28  29 1
            31   29  30 1
            32   18  30 2
            33   28  31 1

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