KEGG   DRUG: D07185Help
Entry
D07185                      Drug                                   

Name
Fendiline (INN)
Formula
C23H25N
Exact mass
315.1987
Mol weight
315.4513
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Calcium antagonist;
Coronary vasodilator
Remark
ATC code: 
Target
calcium channel L type blocker [HSA:775 776 778 779] [KO:K04850 K04851 K04853 K04857]
  Pathway
hsa04010  MAPK signaling pathway
hsa04020  Calcium signaling pathway
hsa04270  Vascular smooth muscle contraction  
 
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C08 CALCIUM CHANNEL BLOCKERS
   C08E NON-SELECTIVE CALCIUM CHANNEL BLOCKERS
    C08EA Phenylalkylamine derivatives
     C08EA01 Fendiline
      D07185  Fendiline (INN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Voltage-gated cation channels
   Ca2+ channel, CACN alpha-1, CaVx.x
    calcium channel L type [HSA:775 776 778 779] [KO:K04850 K04851 K04853 K04857]
     Fendiline [ATC:C08EA01]
      D07185  Fendiline (INN)
BRITE hierarchy
Other DBs
CAS: 
13042-18-7
PubChem: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        24
            1   C8x C     9.6600  -11.7600
            2   C8x C     9.6600  -13.1600
            3   C8x C    10.8724  -13.8600
            4   C8x C    12.0849  -13.1600
            5   C8y C    12.0849  -11.7600
            6   C8x C    10.8724  -11.0600
            7   C1c C    13.3160  -11.0490
            8   C8y C    14.5212  -11.7447
            9   C8x C    14.5216  -13.1596
            10  C8x C    15.7342  -13.8593
            11  C8x C    16.9465  -13.1589
            12  C8x C    16.9460  -11.7439
            13  C8x C    15.7334  -11.0443
            14  C1b C    13.3157   -9.6601
            15  C1b C    14.5162   -8.9666
            16  N1b N    15.7062   -9.6535
            17  C1c C    16.8960   -8.9662
            18  C8y C    18.0863   -9.6532
            19  C1a C    16.8959   -7.5602
            20  C8x C    18.0866  -11.0597
            21  C8x C    19.2992  -11.7595
            22  C8x C    20.5115  -11.0592
            23  C8x C    20.5112   -9.6527
            24  C8x C    19.2986   -8.9530
BOND        26
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11   10  11 2
            12   11  12 1
            13   12  13 2
            14    8  13 1
            15    7  14 1
            16   14  15 1
            17   15  16 1
            18   16  17 1
            19   17  18 1
            20   17  19 1
            21   18  20 2
            22   20  21 1
            23   21  22 2
            24   22  23 1
            25   23  24 2
            26   18  24 1

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