KEGG   DRUG: FendilineHelp
Entry
D07185                      Drug                                   

Name
Fendiline (INN)
Formula
C23H25N
Exact mass
315.1987
Mol weight
315.4513
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Cardiovascular agent
 DG01653  Antiarrhythmics
  DG01807  Phenylalkylamine derivative
Other
 DG01575  Calcium channel blocker
  DG01496  Calcium channel L type blocker
Remark
ATC code: 
Chemical group: 
Activity
Calcium antagonist, Coronary vasodilator
Target
calcium channel L type blocker [HSA:775 776 778 779] [KO:K04850 K04851 K04853 K04857]
  Pathway
MAPK signaling pathway
Calcium signaling pathway
Vascular smooth muscle contraction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C08 CALCIUM CHANNEL BLOCKERS
   C08E NON-SELECTIVE CALCIUM CHANNEL BLOCKERS
    C08EA Phenylalkylamine derivatives
     C08EA01 Fendiline
      D07185  Fendiline (INN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Voltage-gated cation channels
   Ca2+ channel, CACN alpha-1, CaVx.x
    calcium channel L type
     Fendiline
      D07185  Fendiline (INN)
BRITE hierarchy
Other DBs
CAS: 
13042-18-7
PubChem: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        24
            1   C8x C     9.6600  -11.7600
            2   C8x C     9.6600  -13.1600
            3   C8x C    10.8724  -13.8600
            4   C8x C    12.0849  -13.1600
            5   C8y C    12.0849  -11.7600
            6   C8x C    10.8724  -11.0600
            7   C1c C    13.3160  -11.0490
            8   C8y C    14.5212  -11.7447
            9   C8x C    14.5216  -13.1596
            10  C8x C    15.7342  -13.8593
            11  C8x C    16.9465  -13.1589
            12  C8x C    16.9460  -11.7439
            13  C8x C    15.7334  -11.0443
            14  C1b C    13.3157   -9.6601
            15  C1b C    14.5162   -8.9666
            16  N1b N    15.7062   -9.6535
            17  C1c C    16.8960   -8.9662
            18  C8y C    18.0863   -9.6532
            19  C1a C    16.8959   -7.5602
            20  C8x C    18.0866  -11.0597
            21  C8x C    19.2992  -11.7595
            22  C8x C    20.5115  -11.0592
            23  C8x C    20.5112   -9.6527
            24  C8x C    19.2986   -8.9530
BOND        26
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11   10  11 2
            12   11  12 1
            13   12  13 2
            14    8  13 1
            15    7  14 1
            16   14  15 1
            17   15  16 1
            18   16  17 1
            19   17  18 1
            20   17  19 1
            21   18  20 2
            22   20  21 1
            23   21  22 2
            24   22  23 1
            25   23  24 2
            26   18  24 1

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