KEGG   DRUG: D07784Help
Entry
D07784                      Drug                                   
Name
Delorazepam (INN);
Dadumir (TN)
Formula
C15H10Cl2N2O
Exact mass
304.017
Mol weight
305.1587
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Transquilizer
Comment
Benzodiazepines
See Lorazepam [DR:D00365]
Target
GABAA-receptor (benzodiazepine binding site) agonist [HSA:2554 2555 2556 2557 2558 2559 2560 2561 2562 2563 2564 2565 2566 2567 2568 55879] [KO:K05175 K05181 K05184 K05185 K05186 K05189 K05192]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04727  GABAergic synapse  
 
Brite
Target-based classification of drugs [BR:br08310]
 Ion channels
  Cys-loop superfamily
   GABA-A
    GABAA-receptor (benzodiazepine binding site) [HSA:2554 2555 2556 2557 2558 2559 2560 2561 2562 2563 2564 2565 2566 2567 2568 55879] [KO:K05175 K05176 K05177 K05178 K05179 K05180 K05181 K05182 K05183 K05184 K05185 K05186 K05187 K05188 K05189 K05192]
     Delorazepam
      D07784  Delorazepam (INN)
BRITE hierarchy
Other DBs
CAS: 
2894-67-9
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        20
            1   C8y C    22.6200  -17.2747
            2   N1x N    23.7167  -16.4110
            3   C5x C    25.0821  -16.7224
            4   C1x C    25.6840  -17.9756
            5   C8y C    22.6200  -18.6837
            6   N2x N    25.0830  -19.2429
            7   C2y C    23.7167  -19.5545
            8   C8x C    21.4076  -16.5747
            9   C8x C    20.1951  -17.2747
            10  C8y C    20.1951  -18.6837
            11  C8x C    21.4076  -19.3837
            12  C8y C    23.4125  -20.8935
            13  C8x C    22.0558  -21.3143
            14  C8x C    21.7463  -22.6796
            15  C8x C    22.7740  -23.6303
            16  C8x C    24.1308  -23.2096
            17  C8y C    24.4402  -21.8442
            18  X   Cl   25.7692  -21.4321
            19  X   Cl   19.0065  -19.3704
            20  O5x O    25.9431  -15.6436
BOND        22
            1     3   4 1
            2     1   5 1
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 2
            8     1   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    5  11 2
            13    7  12 1
            14   12  13 2
            15   13  14 1
            16   14  15 2
            17   15  16 1
            18   16  17 2
            19   12  17 1
            20   17  18 1
            21   10  19 1
            22    3  20 2

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