| Entry |
|
|---|
| Name |
Dexfenfluramine (INN)
|
|---|
| Formula |
C12H16F3N
|
|---|
| Exact mass |
231.1235
|
|---|
| Mol weight |
231.2574
|
|---|
| Structure |
     |
|---|
| Activity |
Anorexic
|
|---|
| Remark |
|
|---|
| Target |
serotonin transporter inhibitor [HSA: 6532] [KO: K05037]; serotonin releaser |
|---|
| Pathway |
|
|---|
| Metabolism |
Enzyme: CYP2D6 [HSA: 1565]
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A08 ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS
A08A ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS
A08AA Centrally acting antiobesity products
A08AA04 Dexfenfluramine
D07805 Dexfenfluramine (INN)
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A3 (dopamine transporter) [HSA:6531] [KO:K05036]
Dexfenfluramine [ATC:A08AA04]
D07805 Dexfenfluramine (INN)
 |
|---|
| Other DBs |
CAS: 3239-44-9 PubChem: DrugBank: LigandBox: NIKKAJI: |
|---|
| KCF data |
ATOM 16
1 C1b C 23.5900 -18.7600
2 C1c C 22.3300 -18.0600
3 N1b N 21.1400 -18.7600
4 C8y C 24.8500 -18.0600
5 C8x C 26.0400 -18.6900
6 C8y C 27.2300 -17.9900
7 C8x C 27.2300 -16.5900
8 C8x C 26.0400 -15.9600
9 C8x C 24.8500 -16.6600
10 C1d C 28.4200 -18.7600
11 X F 29.6800 -19.4600
12 X F 29.1200 -17.5000
13 X F 27.7900 -19.9500
14 C1a C 22.3300 -16.6600
15 C1b C 19.9500 -18.0600
16 C1a C 18.6900 -18.7600
BOND 16
1 1 2 1
2 2 3 1
3 1 4 1
4 4 5 2
5 5 6 1
6 6 7 2
7 7 8 1
8 8 9 2
9 4 9 1
10 6 10 1
11 10 11 1
12 10 12 1
13 10 13 1
14 2 14 1 #Up
15 3 15 1
16 15 16 1
|
|---|
