KEGG   DRUG: D09029Help
Entry
D09029                      Drug                                   

Name
Velaglucerase alfa (genetical recombination) (JAN);
Velaglucerase alfa (USAN);
Vpriv (TN)
Product
Formula
C2532H3854N672O711S16
Exact mass
55562.1608
Mol weight
55596.809
Sequence
ARPCIPKSFG YSSVVCVCNA TYCDSFDPPT FPALGTFSRY ESTRSGRRME LSMGPIQANH
TGTGLLLTLQ PEQKFQKVKG FGGAMTDAAA LNILALSPPA QNLLLKSYFS EEGIGYNIIR
VPMASCDFSI RTYTYADTPD DFQLHNFSLP EEDTKLKIPL IHRALQLAQR PVSLLASPWT
SPTWLKTNGA VNGKGSLKGQ PGDIYHQTWA RYFVKFLDAY AEHKLQFWAV TAENEPSAGL
LSGYPFQCLG FTPEHQRDFI ARDLGPTLAN STHHNVRLLM LDDQRLLLPH WAKVVLTDPE
AAKYVHGIAV HWYLDFLAPA KATLGETHRL FPNTMLFASE ACVGSKFWEQ SVRLGSWDRG
MQYSHSIITN LLYHVVGWTD WNLALNPEGG PNWVRNFVDS PIIVDITKDT FYKQPMFYHL
GHFSKFIPEG SQRVGLVASQ KNDLDAVALM HPDGSAVVVV LNRSSKDVPL TIKDPAVGFL
ETISPGYSIH TYLWRRQ (Glycosylation site: 19; 59; 146; 270; 462)
  Type
Peptide
Activity
Treatment of patients with Gaucher disease [DS:H00126]
Remark
Therapeutic category: 
ATC code: 
Comment
human recombinant glucocerebrosidase [HSA:2629] [KO:K01201] [EC:3.2.1.45]
Interaction
Genomic biomarker: GBA [HSA:2629]
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A16 OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
   A16A OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
    A16AB Enzymes
     A16AB10 Velaglucerase alfa
      D09029  Velaglucerase alfa (USAN)
USP drug classification [BR:br08302]
 Enzyme Replacement/Modifiers
  Velaglucerase alfa
   D09029  Velaglucerase alfa (USAN)
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   395  Enzyme preparations
    3959  Others
     D09029  Velaglucerase alfa (genetical recombination) (JAN); Velaglucerase alfa (USAN)
BRITE hierarchy
Other DBs
CAS: 
884604-91-5
PubChem: 
LinkDB All DBs

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