KEGG   DRUG: Collagenase clostridium histolyticumHelp
Entry
D09596                      Drug                                   

Name
Collagenase clostridium histolyticum (USAN);
Collagenase (Clostridium histolyticum) (JAN);
Xiaflex (TN)
Product
Remark
Therapeutic category: 
ATC code: 
Efficacy
Collagen hydrolysis
Comment
Formula:
C5632H8679N1481O1785S17 (Clostridium histolyticum gene colG isoenzyme AUX-I)
C5220H7993N1353O1617S25 (Clostridium histolyticum gene colH isoenzyme AUX-II)
Collagenase clostridium histolyticum [EC:3.4.24.3] is bacterial enzymes produced the Clostridium histolyticum.
Treatment of Dupuytren's disease
Target
Collagen
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 M MUSCULO-SKELETAL SYSTEM
  M09 OTHER DRUGS FOR DISORDERS OF THE MUSCULO-SKELETAL SYSTEM
   M09A OTHER DRUGS FOR DISORDERS OF THE MUSCULO-SKELETAL SYSTEM
    M09AB Enzymes
     M09AB02 Collagenase clostridium histolyticum
      D09596  Collagenase clostridium histolyticum (USAN)
USP drug classification [BR:br08302]
 Dermatological Agents
  Collagenase
   D09596  Collagenase clostridium histolyticum (USAN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  29  Other agents affecting individual organs
   290  Other agents affecting individual organs
    2900  Other agents affecting individual organs
     D09596  Collagenase clostridium histolyticum (USAN); Collagenase (Clostridium histolyticum) (JAN)
Target-based classification of drugs [BR:br08310]
 Others
  Other
   Collagen
    D09596  Collagenase clostridium histolyticum (USAN)
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D09596
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D09596
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D09596
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D09596
Orphan drugs in the USA [br08355.html]
 Orphan drugs in the USA
  D09596
BRITE hierarchy
Other DBs
CAS: 
955089-04-0 955089-06-2
PubChem: 
LinkDB All DBs

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