KEGG   DRUG: D09978Help
Entry
D09978                      Drug                                   

Name
Tofogliflozin hydrate (JAN);
Tofogliflozin (USAN);
Apleway (TN);
Deberza (TN)
Formula
C22H26O6. H2O
Exact mass
404.1835
Mol weight
404.4535
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Treatment of diabetes mellitus [DS:H00409]
Remark
Therapeutic category: 
Target
sodium glucose co-transporter2 (SGLT2) inhibitor [HSA:6524] [KO:K14382]
Interaction
Drug interaction
Structure map
Antidiabetics
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   396  Antidiabetic agents
    3969  Others
     D09978  Tofogliflozin hydrate (JAN); Tofogliflozin (USAN)
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC5
    SLC5A2
     Tofogliflozin
      D09978  Tofogliflozin hydrate (JAN); Tofogliflozin (USAN)
BRITE hierarchy
Other DBs
CAS: 
1201913-82-7
PubChem: 
LigandBox: 
LinkDB All DBs
KCF data Show

ATOM        29
            1   O0  O    22.8312  -19.4121
            2   C1y C    12.7429  -15.8246
            3   C1y C    12.7429  -17.2251
            4   C1y C    13.9333  -17.9253
            5   C1z C    15.1936  -17.2251
            6   O2x O    15.1936  -15.8246
            7   C1y C    13.9333  -15.1244
            8   C1b C    13.9333  -13.7240
            9   O1a O    11.5525  -17.9253
            10  O1a O    11.5525  -15.1244
            11  O1a O    13.9333  -19.3257
            12  O1a O    15.1236  -13.0237
            13  O2x O    15.1936  -18.6255
            14  C1x C    16.5241  -19.0456
            15  C8y C    17.3643  -17.9253
            16  C8y C    16.5241  -16.8049
            17  C8x C    18.7648  -17.7852
            18  C8x C    19.3249  -16.4548
            19  C8y C    18.4847  -15.3345
            20  C8x C    17.0842  -15.5445
            21  C1b C    19.6751  -14.6342
            22  C8y C    20.8654  -15.3345
            23  C8x C    20.8654  -16.7349
            24  C8x C    22.1258  -17.4351
            25  C8y C    23.3162  -16.7349
            26  C8x C    23.3162  -15.3345
            27  C8x C    22.1258  -14.6342
            28  C1b C    24.5066  -17.4351
            29  C1a C    25.6969  -16.7349
BOND        31
            1     2   3 1
            2     3   4 1
            3     4   5 1
            4     5   6 1
            5     6   7 1
            6     2   7 1
            7     7   8 1 #Up
            8     3   9 1 #Up
            9     2  10 1 #Down
            10    4  11 1 #Down
            11    8  12 1
            12    5  13 1 #Down
            13   13  14 1
            14   14  15 1
            15   15  16 2
            16    5  16 1 #Up
            17   15  17 1
            18   17  18 2
            19   18  19 1
            20   19  20 2
            21   16  20 1
            22   21  22 1
            23   21  19 1
            24   22  23 2
            25   23  24 1
            26   24  25 2
            27   25  26 1
            28   26  27 2
            29   22  27 1
            30   25  28 1
            31   28  29 1

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