KEGG   DISEASE: Bacterial vaginosis
Entry
H01380                      Disease                                
Name
Bacterial vaginosis
Description
Bacterial vaginosis (BV) flora is dominated by Gardnerella vaginalis and includes many anaerobic organisms as contrasted with normal lactobacillus-dominated vaginal flora. BV flora is thought to be related to vaginal discharge, poor pregnancy outcomes, pelvic inflammatory disease, postoperative wound infections, endometritis following elective abortions. Additionally, BV flora predisposes women to infection by HIV as well as other Sexually Transmitted Diseases (STDs).
Category
Bacterial infectious disease
Brite
Human diseases in ICD-11 classification [BR:br08403]
 21 Symptoms, signs or clinical findings, not elsewhere classified
  Symptoms, signs or clinical findings of the genitourinary system
   Symptoms, signs or clinical findings involving the female genital system
    MF3A  Vaginal discharge
     H01380  Bacterial vaginosis
Genome-based classification of infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by actinobacteria
   H01380  Bacterial vaginosis
Pathogen
Gardnerella vaginalis [GN:gvg]
Drug
Metronidazole [DR:D00409]
Tinidazole [DR:D01426]
Secnidazole [DR:D07353]
Other DBs
ICD-11: MF3A
ICD-10: N76
MeSH: D016585
Reference
PMID:20865041
  Authors
Yeoman CJ, Yildirim S, Thomas SM, Durkin AS, Torralba M, Sutton G, Buhay CJ, Ding Y, Dugan-Rocha SP, Muzny DM, Qin X, Gibbs RA, Leigh SR, Stumpf R, White BA, Highlander SK, Nelson KE, Wilson BA
  Title
Comparative genomics of Gardnerella vaginalis strains reveals substantial differences in metabolic and virulence potential.
  Journal
PLoS One 5:e12411 (2010)
DOI:10.1371/journal.pone.0012411
Reference
PMID:22143133
  Authors
Martin DH
  Title
The microbiota of the vagina and its influence on women's health and disease.
  Journal
Am J Med Sci 343:2-9 (2012)
DOI:10.1097/MAJ.0b013e31823ea228
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