KEGG   PATHWAY: bcx02030Help
Entry
bcx02030                    Pathway                                

Name
Bacterial chemotaxis - Bacillus cereus 03BB102
Description
Chemotaxis is the process by which cells sense chemical gradients in their environment and then move towards more favorable conditions. In chemotaxis, events at the receptors control autophosphorylation of the CheA histidine kinase, and the phosphohistidine is the substrate for the response regulator CheY, which catalyzes the transfer of the phosphoryl group to a conserved aspartate. The resulting CheY-P can interact with the switch mechanism in the motor. This interaction causes a change in behavior, such as in direction or speed of rotation of flagella.
Class
Cellular Processes; Cell motility
BRITE hierarchy
Pathway map
bcx02030  Bacterial chemotaxis
bcx02030

Ortholog table
Other DBs
BSID: 93542
GO: 0006935
Organism
Bacillus cereus 03BB102 [GN:bcx]
Gene
BCA_0606  methyl-accepting chemotaxis protein [KO:K03406]
BCA_2090  methyl-accepting chemotaxis protein [KO:K03406]
BCA_0720  methyl-accepting chemotaxis protein [KO:K03406]
BCA_0446  methyl-accepting chemotaxis protein [KO:K03406]
BCA_0457  methyl-accepting chemotaxis protein [KO:K03406]
BCA_5160  methyl-accepting chemotaxis protein [KO:K03406]
BCA_5186  methyl-accepting chemotaxis protein [KO:K03406]
BCA_5187  methyl-accepting chemotaxis protein [KO:K03406]
BCA_5219  methyl-accepting chemotaxis protein [KO:K03406]
BCA_3337  methyl-accepting chemotaxis protein [KO:K03406]
BCA_0594  methyl-accepting chemotaxis protein [KO:K03406]
BCA_0707  rbsB; ribose ABC transporter, ribose-binding protein [KO:K10439]
BCA_1691  chemotaxis protein CheA [KO:K03407] [EC:2.7.13.3]
BCA_1033  sensor histidine kinase/response regulator [KO:K03407] [EC:2.7.13.3]
BCA_1690  chemotaxis response regulator [KO:K03413]
BCA_1717  chemotaxis protein CheV [KO:K03415]
BCA_1032  methyltransferase, CheR family [KO:K00575] [EC:2.1.1.80]
BCA_1695  cheR; chemotaxis protein methyltransferase CheR [KO:K00575] [EC:2.1.1.80]
BCA_1708  fliG; flagellar motor switch protein FliG [KO:K02410]
BCA_1723  putative flagellar motor switch protein FliM [KO:K02416]
BCA_1692  putative flagellar motor switch protein [KO:K02417]
BCA_1722  conserved domain protein [KO:K02417]
BCA_1724  putative flagellar motor switch protein FliN [KO:K02417]
BCA_1688  putative chemotaxis protein MotA [KO:K02556]
BCA_4618  chemotaxis protein MotA [KO:K02556]
BCA_1689  putative chemotaxis protein MotB [KO:K02557]
BCA_4617  chemotaxis protein MotB [KO:K02557]
Compound
C00049  L-Aspartate
C00107  Dipeptide
C00121  D-Ribose
C00124  D-Galactose
C00208  Maltose
C00716  Serine
Reference
  Authors
Kristich CJ, Ordal GW.
  Title
Bacillus subtilis CheD is a chemoreceptor modification enzyme required for chemotaxis.
  Journal
J Biol Chem 277:25356-62 (2002)
DOI:10.1074/jbc.M201334200
Reference
  Authors
Kirby JR, Kristich CJ, Saulmon MM, Zimmer MA, Garrity LF, Zhulin IB, Ordal GW.
  Title
CheC is related to the family of flagellar switch proteins and acts independently from CheD to control chemotaxis in Bacillus subtilis.
  Journal
Mol Microbiol 42:573-85 (2001)
DOI:10.1046/j.1365-2958.2001.02581.x
Reference
  Authors
Szurmant H, Bunn MW, Cannistraro VJ, Ordal GW.
  Title
Bacillus subtilis hydrolyzes CheY-P at the location of its action, the flagellar switch.
  Journal
J Biol Chem 278:48611-6 (2003)
DOI:10.1074/jbc.M306180200
Reference
  Authors
Szurmant H, Muff TJ, Ordal GW.
  Title
Bacillus subtilis CheC and FliY are members of a novel class of CheY-P-hydrolyzing proteins in the chemotactic signal transduction cascade.
  Journal
J Biol Chem 279:21787-92 (2004)
DOI:10.1074/jbc.M311497200
Reference
  Authors
Yoshihara S, Geng X, Okamoto S, Yura K, Murata T, Go M, Ohmori M, Ikeuchi M.
  Title
Mutational analysis of genes involved in pilus structure, motility and transformation competency in the unicellular motile cyanobacterium Synechocystis sp. PCC 6803.
  Journal
Plant Cell Physiol 42:63-73 (2001)
Reference
PMID:8104179
  Authors
Darzins A.
  Title
The pilG gene product, required for Pseudomonas aeruginosa pilus production and twitching motility, is homologous to the enteric, single-domain response regulator CheY.
  Journal
J Bacteriol 175:5934-44 (1993)
DOI:10.1128/JB.175.18.5934-5944.1993
Reference
  Authors
Szurmant H, Ordal GW
  Title
Diversity in chemotaxis mechanisms among the bacteria and archaea.
  Journal
Microbiol Mol Biol Rev 68:301-19 (2004)
DOI:10.1128/MMBR.68.2.301-319.2004
Reference
  Authors
Rao CV, Glekas GD, Ordal GW
  Title
The three adaptation systems of Bacillus subtilis chemotaxis.
  Journal
Trends Microbiol 16:480-7 (2008)
DOI:10.1016/j.tim.2008.07.003
Reference
  Authors
Muff TJ, Ordal GW
  Title
The diverse CheC-type phosphatases: chemotaxis and beyond.
  Journal
Mol Microbiol 70:1054-61 (2008)
DOI:10.1111/j.1365-2958.2008.06482.x
Reference
  Authors
Miller LD, Russell MH, Alexandre G
  Title
Diversity in bacterial chemotactic responses and niche adaptation.
  Journal
Adv Appl Microbiol 66:53-75 (2009)
DOI:10.1016/S0065-2164(08)00803-4
KO pathway
ko02030   
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